Maculopathies
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A maculopathy is any pathological condition of the
macula The macula (/ˈmakjʊlə/) or macula lutea is an oval-shaped pigmented area in the center of the retina of the human eye and in other animals. The macula in humans has a diameter of around and is subdivided into the umbo, foveola, foveal avas ...
, an area at the centre of the
retina The retina (; or retinas) is the innermost, photosensitivity, light-sensitive layer of tissue (biology), tissue of the eye of most vertebrates and some Mollusca, molluscs. The optics of the eye create a focus (optics), focused two-dimensional ...
that is associated with highly sensitive, accurate vision.


Forms of maculopathies

* Age-Related Macular Degeneration is a degenerative maculopathy associated with progressive sight loss. It is characterised by changes in pigmentation in the
Retinal Pigment Epithelium The pigmented layer of retina or retinal pigment epithelium (RPE) is the pigment A pigment is a powder used to add or alter color or change visual appearance. Pigments are completely or nearly solubility, insoluble and reactivity (chemistry), ...
, the appearance of
drusen Drusen, from the German word for ''node'' or ''geode'' (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. The presence of a ...
on the retina of the eye and
choroidal neovascularization Choroidal neovascularization (CNV) is the creation of new blood vessels in the choroid layer of the eye. Choroidal neovascularization is a common cause of neovascular degenerative maculopathy (i.e. 'wet' macular degeneration) commonly exacerbated ...
. AMD has two forms; 'dry' or atrophic/non-exudative AMD, and 'wet' or exudative/neovascular AMD. *
Malattia Leventinese A maculopathy is any pathological condition of the macula, an area at the centre of the retina that is associated with highly sensitive, accurate vision. Forms of maculopathies * Age-Related Macular Degeneration is a degenerative maculopathy ass ...
(or Doyne’s honeycomb retinal dystrophy) is another maculopathy with a similar pathology to wet AMD. *
Hypotony maculopathy Hypotony maculopathy is maculopathy due to very low intraocular pressure known as ocular hypotony. Maculopathy occurs either due to increased outflow of aqueous humor through angle of anterior chamber or less commonly, due to decreased aqueous h ...
: Maculopathy due to very low
intraocular pressure Intraocular pressure (IOP) is the fluid pressure inside the eye. Tonometry is the method eye care professionals use to determine this. IOP is an important aspect in the evaluation of patients at risk of glaucoma. Most tonometers are calibrated t ...
(
ocular hypotony Ocular hypotony, or ocular hypotension, or shortly hypotony, is the medical condition in which intraocular pressure (IOP) of the eye is very low. Description Normal IOP ranges between 10–20 mm Hg. The eye is considered hypotonous if the IOP is â ...
). *Cellophane Maculopathy A fine glistening membrane forms over the macula, obscuring the vision.Handbook of Ocular Disease Management: Epiretinal membrane
Retrieved on 2008-05-14


See also

*
EFEMP1 EGF-containing fibulin-like extracellular matrix protein 1 is a protein that in humans is encoded by the ''EFEMP1'' gene. Gene This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this fa ...
- a gene thought to be involved with Malattia Leventinese *
Robert Walter Doyne Robert Walter Doyne (1857–1916) was an Anglo-Irish ophthalmologist. He was born in Monart, County Wexford, Ireland, second son of the Reverend Philip Walter Doyne (died 1861), vicar of Monart, and Emily Sophia Richards, daughter of John Godd ...
- the British Ophthalmologist after whom Malattia Leventinese is named *
Age-Related Macular Degeneration Macular degeneration, also known as age-related macular degeneration (AMD or ARMD), is a medical condition which may result in blurred or no vision in the center of the visual field. Early on there are often no symptoms. Some people experien ...
*
Retinitis Pigmentosa Retinitis pigmentosa (RP) is a member of a group of genetic disorders called inherited retinal dystrophy (IRD) that cause loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visua ...
*
Malattia Leventinese A maculopathy is any pathological condition of the macula, an area at the centre of the retina that is associated with highly sensitive, accurate vision. Forms of maculopathies * Age-Related Macular Degeneration is a degenerative maculopathy ass ...


References

{{Authority control Eye diseases Channelopathies Blindness