Macromerine is a
phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace am ...
derivative. It was first identified from the cactus ''
Coryphantha macromeris''. It can also be found in ''C. runyonii'', ''C. elephantidens'', and other related members of the family
Cactaceae
A cactus (, or less commonly, cactus) is a member of the plant family Cactaceae, a family comprising about 127 genera with some 1750 known species of the order Caryophyllales. The word ''cactus'' derives, through Latin, from the Ancient Greek ...
. The plants may have been used by
Tarahumara shamans
Shamanism is a religious practice that involves a practitioner (shaman) interacting with what they believe to be a Spirit world (Spiritualism), spirit world through Altered state of consciousness, altered states of consciousness, such as tranc ...
for their
entheogen
Entheogens are psychoactive substances that induce alterations in perception, mood, consciousness, cognition, or behavior for the purposes of engendering spiritual development or otherwiseRätsch, Christian, ''The Encyclopedia of Psychoact ...
ic effects.
Chemistry
Macromerine is a phenethylamine derivative with the molecular formula C
12H
19NO
3.
Effects
At least one study found macromerine to be non-psychoactive,
however as a phenethylamine derivative, it may be psychoactive.
See also
*
Phenethylamine cactus
Many cacti are known to be psychoactive, containing phenethylamine alkaloids such as mescaline. However, the two main ritualistic (folkloric) genera are ''Echinopsis'', of which the most psychoactive species is the San Pedro cactus (''Echinopsis p ...
*
Mescaline
Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin.
Biological ...
References
{{Phenethylamines
Phenethylamine alkaloids
Phenethylamines
Phenol ethers
Phenylethanolamines