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MDL Chime was a free plugin used by
web browsers A web browser, often shortened to browser, is an application for accessing websites. When a user requests a web page from a particular website, the browser retrieves its files from a web server and then displays the page on the user's scree ...
to display the
three-dimensional In geometry, a three-dimensional space (3D space, 3-space or, rarely, tri-dimensional space) is a mathematical space in which three values (''coordinates'') are required to determine the position (geometry), position of a point (geometry), poi ...
structures of
molecules A molecule is a group of two or more atoms that are held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions that satisfy this criterion. In quantum physics, organic chemistry ...
. and was based on the
RasMol RasMol is a computer program written for molecular graphics visualization intended and used mainly to depict and explore biological macromolecule structures, such as those found in the Protein Data Bank (PDB). History It was originally develo ...
code.


Plug-in

Chime was used by a wide range of
biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...
web sites for the visualization of
macromolecules A macromolecule is a "molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." Polymers are physi ...
, many of which were linked to the ''World Index of Molecular Visualization Resources'' MolVisIndex.Org. Chime was also used until 2006 at the
Protein Data Bank The Protein Data Bank (PDB) is a database for the three-dimensional structural data of large biological molecules such as proteins and nucleic acids, which is overseen by the Worldwide Protein Data Bank (wwPDB). This structural data is obtained a ...
(PDB) to examine structures stored there. Although available in 1996 in both
Windows 95 Windows 95 is a consumer-oriented operating system developed by Microsoft and the first of its Windows 9x family of operating systems, released to manufacturing on July 14, 1995, and generally to retail on August 24, 1995. Windows 95 merged ...
and
classic Mac OS Mac OS (originally System Software; retronym: Classic Mac OS) is the series of operating systems developed for the Mac (computer), Macintosh family of personal computers by Apple Computer, Inc. from 1984 to 2001, starting with System 1 and end ...
versions for both
Netscape Netscape Communications Corporation (originally Mosaic Communications Corporation) was an American independent computer services company with headquarters in Mountain View, California, and then Dulles, Virginia. Its Netscape web browser was o ...
and
Internet Explorer Internet Explorer (formerly Microsoft Internet Explorer and Windows Internet Explorer, commonly abbreviated as IE or MSIE) is a deprecation, retired series of graphical user interface, graphical web browsers developed by Microsoft that were u ...
browsers, development of Chime did not follow the move to
Mac OS X macOS, previously OS X and originally Mac OS X, is a Unix, Unix-based operating system developed and marketed by Apple Inc., Apple since 2001. It is the current operating system for Apple's Mac (computer), Mac computers. With ...
for the Mac and support for Windows-based browsers other than Internet Explorer was limited (although it works well in
Mozilla Firefox Mozilla Firefox, or simply Firefox, is a free and open-source web browser developed by the Mozilla Foundation and its subsidiary, the Mozilla Corporation. It uses the Gecko rendering engine to display web pages, which implements curren ...
). One significant feature added in 1997 was the ability to display spectroscopic data in the form of the IUPAC JCAMP-DX protocols. Apart from this, most subsequent updates were for the installation package to follow the development of Windows and Internet Explorer. Accelrys announced in 2012 that Chime was no longer supported and would remain available for download until the end of 2012. Chime was part of the ISIS product line acquired by
Symyx Technologies Symyx Technologies, Inc. was a company that specialized in informatics and automation products. Symyx provided software solutions for scientific research, including Enterprise Laboratory Notebooks and products for combinatorial chemistry. The sof ...
from scientific publisher
Elsevier Elsevier ( ) is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as ''The Lancet'', ''Cell (journal), Cell'', the ScienceDirect collection of electronic journals, ...
in October 2007. Now Chime is owned by Dassault Systemes BIOVIA (formerly Accelrys), and has been merged into
Discovery Studio Discovery Studio is a suite of software for simulating small molecule and macromolecule systems. It is developed and distributed by Dassault Systemes BIOVIA (formerly Accelrys). The product suite has a strong academic collaboration programme, sup ...
, but no longer exists as a free browser plugin. Chime largely has been superseded by
Jmol Jmol is computer software for molecular modelling of chemical structures in 3 dimensions. It is an open-source Java viewer for chemical structures in 3D. The name originated from ''Jva (the programming language) + olcules, and also the m ...
, a non-proprietary
open-source Open source is source code that is made freely available for possible modification and redistribution. Products include permission to use and view the source code, design documents, or content of the product. The open source model is a decentrali ...
Java molecular visualization application and JavaScript applet that has maintained most Chime command compatibility while adding numerous features.


See also

*
List of molecular graphics systems This is a list of notable software systems that are used for visualizing macromolecules. Key The tables below indicate which types of data can be visualized in each system: See also * Biological data visualization * Comparison of nucleic ...
*
ISIS/Draw ISIS/Draw was a chemical structure drawing program developed by MDL Information Systems. It introduced a number of file formats for the storage of chemical information that have become industry standards. History Molecular Design Limited (MDL) wa ...
*
Molecular graphics Molecular graphics is the discipline and philosophy of studying molecules and their properties through graphical representation. IUPAC limits the definition to representations on a "graphical display device". Ever since Dalton's atoms and Keku ...
*
Discovery Studio Discovery Studio is a suite of software for simulating small molecule and macromolecule systems. It is developed and distributed by Dassault Systemes BIOVIA (formerly Accelrys). The product suite has a strong academic collaboration programme, sup ...


References


External links


Screen Capture of Chime in Action

Accelrys Chime

Chime Download
{dead link, date=May 2017 , bot=InternetArchiveBot , fix-attempted=yes
RCSB Protein Data Bank

MolviZ.Org: Molecular Visualization Resources
with rich collection of molecules
Dublin City University CHIME and Jmol Pages
Molecular geometry