Mitogen-activated protein kinase kinase kinase kinase (MAP4K) is a family of proteins involved in cellular
signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a biochemical cascade, series of molecular events. Proteins responsible for detecting stimuli are generally termed receptor (biology), rece ...
.
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MAP4K1
Mitogen-activated protein kinase kinase kinase kinase 1 is a protein kinase that in humans is encoded by the ''MAP4K1'' gene. It is also known as HPK1 (Hematopoietic Progenitor Kinase 1). The protein has been shown to play a role in JNK activati ...
(aka HPK1)
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MAP4K2 (aka GCK)
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MAP4K3 (aka GLK)
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MAP4K4
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) – also known as hepatocyte progenitor kinase-like/germinal center kinase-like kinase (HGK) and Nck-interacting kinase (NIK) – is an enzyme, specifically a serine/threonine (S/T) ...
(aka HGK)
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MAP4K5
Mitogen-activated protein kinase kinase kinase kinase 5 is an enzyme that in humans is encoded by the ''MAP4K5'' gene.
This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Y ...
(aka KHS)
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MAP4K6 (aka MINK)
Images
File:Signal transduction pathways.svg, Some signal transduction pathways. MAP4K is not labelled.
File:MAPKpathway.jpg, MAPK pathway. Some (or all) of the MAP4Ks in this image are labelled by other names, such as HPK1 and GCK.
See also
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Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a biochemical cascade, series of molecular events. Proteins responsible for detecting stimuli are generally termed receptor (biology), rece ...
*
MAP kinase
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammato ...
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MAP kinase kinase
Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK).
MAP2K is classified as .
There are seven genes:
* (a.k.a. MEK1)
* (a ...
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MAP kinase kinase kinase
Mitogen Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently, MAP kinase kinase activates MAP kinase. Several types of MAPKKK ca ...
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List of unusual biological names
This is a list of unusual biological names, given to biological inventions and discoveries. One might consider the listed names unusual due to their containing pop culture references or puns. Genes and proteins
In the early days of genomics, genes ...
References
{{biochemistry-stub
Protein families