Marie Celeste Simon is the Arthur H. Rubenstein Professor of cell and developmental biology, the scientific director of the Abramson Family Cancer Research Institute, and the associate director of the Abramson Cancer Center Core Facilities, at the University of Pennsylvania Perelman School of Medicine. Her research focuses on cancer

cell metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cell ...

angiogenesis Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, formed in the earlier stage of vasculogenesis. Angiogenesis continues the growth of the vasculature by processes of sprouting and splitting ...

, and

immunology Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there ...

. Simon earned a B.A. from

Miami University Miami University (informally Miami of Ohio or simply Miami) is a public research university in Oxford, Ohio. The university was founded in 1809, making it the second-oldest university in Ohio (behind Ohio University, founded in 1804) and the 10 ...

in 1977, and a

M.S. A Master of Science ( la, Magisterii Scientiae; abbreviated MS, M.S., MSc, M.Sc., SM, S.M., ScM or Sc.M.) is a master's degree in the field of science awarded by universities in many countries or a person holding such a degree. In contrast to ...

from

Ohio State University The Ohio State University, commonly called Ohio State or OSU, is a public land-grant research university in Columbus, Ohio. A member of the University System of Ohio, it has been ranked by major institutional rankings among the best publ ...

in 1980, both in

microbiology Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, prot ...

. She earned a

Ph.D. A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is a ...

molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...

from The Rockefeller University in 1985. She did postdoctoral research with

Joseph Nevins Joseph Nevins is an American author, activist and associate professor of geography at Vassar College in New York. Background Joseph Nevins studies socio-territorial boundaries and mobility, imperialism, global apartheid and forms of political vio ...

at Rockefeller, and with

Stuart Orkin Stuart Holland Orkin is an American physician, stem cell biologist and researcher in pediatric hematology-oncology. He is the David G. Nathan Distinguished Professor of Pediatrics at Harvard Medical School. Orkin's research has focused on the gen ...

Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...

. In 1992, Simon became an Assistant Professor of Medicine and Molecular Genetics and Cell Biology at the

University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the b ...

. She became a professor at the University of Pennsylvania School of Medicine in 1999. Simon was an

HHMI investigator The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...

from 1994 to 2014. In 2017, she was awarded the

National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...

Outstanding Investigator Award. She was elected to the National Academy of Medicine in 2018. In 2021, she was elected member of the U. S.

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

., entry in member directory:

References

{{DEFAULTSORT:Simon, Marie Celeste University of Pennsylvania faculty Howard Hughes Medical Investigators Members of the National Academy of Medicine Miami University alumni Ohio State University Graduate School alumni Rockefeller University alumni Year of birth missing (living people) Living people Members of the United States National Academy of Sciences