Lipiduria
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Lipiduria or lipuria is the presence of
lipid Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids include storing ...
s in the
urine Urine is a liquid by-product of metabolism in humans and many other animals. In placental mammals, urine flows from the Kidney (vertebrates), kidneys through the ureters to the urinary bladder and exits the urethra through the penile meatus (mal ...
. Lipiduria is most frequently observed in
nephrotic syndrome Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes proteinuria, protein in the urine, hypoalbuminemia, low blood albumin levels, hyperlipidemia, high blood lipids, and significant edema, swelling. Other symptoms ...
where it is passed as
lipoprotein A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid (also known as fat) molecules in water, as in blood plasma or other extracellular fluids. They consist of a triglyceride and cholesterol center, sur ...
s along with other proteins. It has also been reported as a sign following
fat embolism Fat embolism syndrome occurs when adipose tissue, fat enters the blood stream (fat embolism) and results in symptoms. Symptoms generally begin within a day. This may include a petechia, petechial rash, decreased level of consciousness, and shortn ...
. When lipiduria occurs, epithelial cells or macrophages contain endogenous fats. When filled with numerous fat droplets, such cells are called oval fat bodies. Oval fat bodies exhibit a "
Maltese cross The Maltese cross is a cross symbol, consisting of four " V" or arrowhead shaped concave quadrilaterals converging at a central vertex at right angles, two tips pointing outward symmetrically. It is a heraldic cross variant which develope ...
" configuration under
polarized light microscopy Polarized light microscopy can mean any of a number of optical microscopy techniques involving polarized light. Simple techniques include illumination of the sample with polarized light. Directly transmitted light can, optionally, be blocked wi ...
. The Maltese cross appearance occurs because of its liquid-crystalline structure giving it a double refraction (
birefringence Birefringence, also called double refraction, is the optical property of a material having a refractive index that depends on the polarization and propagation direction of light. These optically anisotropic materials are described as birefrin ...
).


See also

* Urostealith


References

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