A limbal nodule is any nodular lesion at the
limbus
Limbus (Lat. "edge, boundary") may refer to:
* Corneal limbus, the border of the cornea and the sclera (the white of the eye)
* Limbus of fossa ovalis, in the heart
* Limbus 3 and Limbus 4, two line-ups of a German avant-garde musical group
* ...
(junction of the
cornea
The cornea is the transparency (optics), transparent front part of the eyeball which covers the Iris (anatomy), iris, pupil, and Anterior chamber of eyeball, anterior chamber. Along with the anterior chamber and Lens (anatomy), lens, the cornea ...
and
sclera
The sclera, also known as the white of the eye or, in older literature, as the tunica albuginea oculi, is the opaque, fibrous, protective outer layer of the eye containing mainly collagen and some crucial elastic fiber.
In the development of t ...
) of the
eye
An eye is a sensory organ that allows an organism to perceive visual information. It detects light and converts it into electro-chemical impulses in neurons (neurones). It is part of an organism's visual system.
In higher organisms, the ey ...
.
The
differential diagnosis
In healthcare, a differential diagnosis (DDx) is a method of analysis that distinguishes a particular disease or condition from others that present with similar clinical features. Differential diagnostic procedures are used by clinicians to di ...
for a limbal nodule can include:
*
Pinguecula
*Early
Pterygium
A pterygium (: ''pterygia'' or ''pterygiums'') is any wing-like triangular membrane occurring in the neck, eyes, knees, elbows, ankles or digits.
The term comes from the Greek word ''pterygion'' meaning "wing".
Types
* Popliteal pterygium syn ...
*
Foreign body
A foreign body (FB) is any object originating outside the body of an organism. In machinery, it can mean any unwanted intruding object.
Most references to foreign bodies involve propulsion through natural orifices into hollow organs.
Foreign b ...
/ foreign body granuloma
*
Phlycten, an inflamed nodule of lymphoid tissue
*
Episcleritis
Episcleritis is a benign, self-limiting inflammatory disease affecting part of the eye called the episclera. The episclera is a thin layer of tissue that lies between the conjunctiva and the connective tissue layer that forms the white of the e ...
*
Scleritis
Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as the sclera. The disease is often contracted through association with other diseases of the body, such as granulomatosis with polyangiitis or rheu ...
*
Granuloma
A granuloma is an aggregation of macrophages (along with other cells) that forms in response to chronic inflammation. This occurs when the immune system attempts to isolate foreign substances that it is otherwise unable to eliminate. Such sub ...
*
Limbal dermoid, a kind of
choristoma
Choristomas, a form of heterotopia, are masses of normal tissues found in abnormal locations. In contrast to a neoplasm or tumor, the growth of a choristoma is normally regulated.
It is different from a hamartoma. The two can be differentiated a ...
(NB: in other organs ''dermoid'' can refer to a
teratoma
A teratoma is a neoplasia, tumor made up of several types of biological tissue, tissue, such as hair, muscle, Human tooth, teeth, or bone. Teratomata typically form in the tailbone (where it is known as a sacrococcygeal teratoma), ovary, or test ...
)
* malignant melanoma
* naevus
References
*
Eye diseases
{{Eye-disease-stub}