Li-Meng Yan
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Li-Meng Yan or Yan Limeng () is a Chinese
virologist Virology is the scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, the ...
, known for her publications and interviews alleging that
SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19, the respiratory illness responsible for the COVID-19 pandemic. The virus previously had the Novel coronavirus, provisional nam ...
was made in a Chinese government
laboratory A laboratory (; ; colloquially lab) is a facility that provides controlled conditions in which scientific or technological research, experiments, and measurement may be performed. Laboratories are found in a variety of settings such as schools ...
. Her publications have been considered flawed by the wider scientific community. In April 2020, she fled to the United States. She co-authored several
preprint In academic publishing, a preprint is a version of a scholarly or scientific paper that precedes formal peer review and publication in a peer-reviewed scholarly or scientific journal. The preprint may be available, often as a non-typeset versi ...
research papers claiming that SARS-CoV-2 was "produced in a laboratory." According to scientific reviewers from the
Johns Hopkins Center for Health Security The Johns Hopkins Center for Health Security (abbreviated CHS) is an independent, nonprofit organization of the Johns Hopkins Bloomberg School of Public Health. The center works to protect people's health from epidemics and pandemics and ensures ...
, Yan's paper offered "contradictory and inaccurate information that does not support their argument," while reviewers from '' Rapid Reviews: COVID-19'' criticised her preprints as not demonstrating "sufficient scientific evidence to support
heir Inheritance is the practice of receiving private property, titles, debts, entitlements, privileges, rights, and obligations upon the death of an individual. The rules of inheritance differ among societies and have changed over time. Offi ...
claims."


Education and early career

Yan is a native of
Qingdao Qingdao, Mandarin: , (Qingdao Mandarin: t͡ɕʰiŋ˧˩ tɒ˥) is a prefecture-level city in the eastern Shandong Province of China. Located on China's Yellow Sea coast, Qingdao was long an important fortress. In 1897, the city was ceded to G ...
, Shandong, China. She received her Master of Medicine from Xiangya Medical College of
Central South University Central South University (CSU; ) is a public university in Changsha, Hunan, China. Funded and overseen by China's Ministry of Education, it is a member of Project 211, Project 985, and the Double First-Class Construction initiatives. History ...
in China. In 2014, she completed a Doctor of Medicine in
ophthalmology Ophthalmology (, ) is the branch of medicine that deals with the diagnosis, treatment, and surgery of eye diseases and disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a ...
from
Southern Medical University Southern Medical University () is a provincial public medical university in Baiyun, Guangzhou, Baiyun, Guangzhou, Guangdong, China. Formerly as a military-affiliated medical university, the whole institution was transferred to the Guangdong Pr ...
in Guangzhou. After this, she was a postdoctoral fellow at the
University of Hong Kong The University of Hong Kong (HKU) is a public research university in Pokfulam, Hong Kong. It was founded in 1887 as the Hong Kong College of Medicine for Chinese by the London Missionary Society and formally established as the University of ...
(HKU) until 2020. Before the
COVID-19 pandemic The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December ...
, Yan had served as a co-author on an article on universal influenza vaccines.


Origins of SARS-CoV-2


Preprint papers

Between September 2020 and March 2021, Yan authored a series of four preprint research papers, wherein she argued that SARS-CoV-2 did not emerge naturally in a "spillover from animals," but rather was produced in a laboratory. Her preprints (which did not undergo a scientific
peer review Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work (:wiktionary:peer#Etymology 2, peers). It functions as a form of self-regulation by qualified members of a profession within the ...
process) were posted to the
Zenodo Zenodo is a general-purpose open repository developed under the European OpenAIRE program and operated by CERN. It allows researchers to deposit research papers, data sets, research software, reports, and any other research related digital art ...
platform, an
open-access repository An open repository or open-access repository is a digital platform that holds research output and provides free, immediate and permanent access to research results for anyone to use, download and distribute. To facilitate open access such reposito ...
where anyone can post their research. Yan stated that evidence of genetic engineering was censored in scientific journals, allegedly as part of a conspiracy to suppress information on the topic. However, other scientists disputed the validity of the papers, pointing to poor methods, undisclosed funding from politically-motivated sources, the use of pseudonyms for the papers' co-authors, and the papers having never been submitted to a journal for review. The papers were described by virologists as "non-scientific," "
junk science Junk science is spurious or fraudulent scientific data, research, or analysis. The concept is often invoked in political and legal contexts where facts and scientific results have a great amount of weight in making a determination. It usually con ...
," and written to spread "political propaganda." Reviewers for MIT '' Rapid Reviews: COVID-19'' (), which seeks out preprint papers and reviews them in an attempt to reduce the spread of false or misleading scientific news, analyzed Yan's study and issued the following statement:
Given the far-reaching implications of the "Yan Report," RR:C19 sought out peer reviews from world-renowned experts in virology,
molecular biology Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactio ...
,
structural biology Structural biology deals with structural analysis of living material (formed, composed of, and/or maintained and refined by living cells) at every level of organization. Early structural biologists throughout the 19th and early 20th centuries we ...
,
computational biology Computational biology refers to the use of techniques in computer science, data analysis, mathematical modeling and Computer simulation, computational simulations to understand biological systems and relationships. An intersection of computer sci ...
, vaccine development, and medicine. Collectively, reviewers have debunked the authors' claims that: (1) bat coronaviruses ZC45 or ZXC21 were used as a background strain to engineer SARS-CoV-2, (2) the presence of restriction sites flanking the suggest prior screening for a virus targeting the human receptor, and (3) the furin-like cleavage site is unnatural and provides evidence of engineering. In all three cases, the reviewers provide counter-arguments based on peer-reviewed literature and long-established foundational knowledge that directly refute the claims put forth by Yan ''et al''. There was a general consensus that the study's claims were better explained by potential political motivations rather than scientific integrity. The peer reviewers arrived at these common opinions independently, further strengthening the credibility of the peer reviews.


Political links

Yan's preprint was promoted by the Rule of Law Society, a political organisation affiliated with
Steve Bannon Stephen Kevin Bannon (born November 27, 1953) is an American media executive, political strategist, and former investment banker. He served as the White House's chief strategist for the first seven months of president Donald Trump's first ...
, former Trump strategist, and
Guo Wengui Guo Wengui (; born May 10, 1970—self claim or October 5, 1968), also known under the Cantonese language, Cantonese name Ho Wan Kwok (), Miles Guo, and Miles Kwok, is a self-exiled Chinese billionaire businessman, political activism, politica ...
, an expatriate Chinese billionaire, in November 2020. The organisation's stated intent was to investigate "Chinese corruption and financially support victims of the regime." The Rule of Law Society had not previously published scientific or medical research. Yan previously appeared on Bannon's "War Room" podcast. The lack of financial disclosure in Yan's papers was described as a lapse in ethical transparency by Dr. Adam Lauring, particularly when publishing "what are essentially conspiracy theories that are not founded in fact". In November 2020, ''The New York Times'' reported that Yan's "trajectory was carefully crafted" by Steve Bannon and Guo Wengui, who played to rising anti-Chinese sentiments, with the goal of bringing down China's government and distracting from the Trump administration's handling of the COVID-19 pandemic. The ''Times'' article pointed out that Guo and Bannon arranged for Yan to fly first class to the United States, arranged lodging, coached her on media appearances, and arranged interviews for her with conservative media hosts such as
Lou Dobbs Louis Carl Dobbs (September 24, 1945 – July 18, 2024) was an American conservative political commentator, author, and television host who presented '' Moneyline'' (later ''Lou Dobbs Tonight'') from 1980 to 2009 and 2011 to 2021. From 2021 unti ...
and
Tucker Carlson Tucker Swanson McNear Carlson (born May 16, 1969) is an American conservative political commentator who hosted the nightly political talk show '' Tucker Carlson Tonight'' on Fox News from 2016 to 2023. Since his contract with Fox News was term ...
.


Media coverage

In an 80-minute show in January 2020, YouTube host Wang Dinggang, also known as "Lu De", said he heard from an unnamed whistleblower who told him China was not being transparent about the outbreak in Wuhan. Wang described his source, who was later revealed to be Yan, as "the world's absolute top coronavirus expert." Although Yan worked at one of the world's top virology labs, she was fairly new to the field of virology and had not studied coronaviruses before the COVID-19 pandemic. Between July and August, Yan was interviewed by
Fox News The Fox News Channel (FNC), commonly known as Fox News, is an American Multinational corporation, multinational Conservatism in the United States, conservative List of news television channels, news and political commentary Television stati ...
,
Newsmax TV Newsmax TV is an American television channel owned by Newsmax described as conservative, right-wing, and far-right. The network primarily focuses on political opinion-based talk shows. It carries a news/talk format throughout the day and night ...
, and the ''
Daily Mail The ''Daily Mail'' is a British daily Middle-market newspaper, middle-market Tabloid journalism, tabloid conservative newspaper founded in 1896 and published in London. , it has the List of newspapers in the United Kingdom by circulation, h ...
''. Yan claimed in interviews that she became aware of person-to-person
transmission of COVID-19 The transmission of COVID-19 is the passing of coronavirus disease 2019 from person to person. COVID-19 is mainly transmitted when people breathe in air contaminated by droplets/aerosols and small airborne particles containing the virus. Inf ...
in late December 2019, and that she attempted to communicate the risks to her superiors in late December 2019 or early January 2020. She stated that the
Chinese government The government of the People's Republic of China is based on a system of people's congress within the parameters of a Unitary state, unitary communist state, in which the ruling Chinese Communist Party (CCP) enacts its policies through people's ...
and the
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
(WHO) knew about the person-to-person transmission of COVID-19 earlier than they reported or made public, and she stated that the Chinese government suppressed both her research and that of others. An official statement issued by HKU on 11 July 2020 confirmed that Yan was formerly a post-doctoral researcher at the institution, but disputed the accuracy of other elements of her account, adding that "Dr. Yan never conducted any research on human-to-human transmission of the novel coronavirus at HKU", and that many of her claims had no scientific basis.


Notes


See also

*
Ai Fen Ai Fen () is a Chinese doctor and director of the emergency department of Central Hospital of Wuhan. In December 2019, she was one of the first doctors to encounter pneumonia patients infected with the then-unknown virus, SARS-CoV-2. On 30 Dec ...


References

{{DEFAULTSORT:Yan, Li-Meng Chinese ophthalmologists Chinese virologists Chinese women scientists Chinese conspiracy theorists COVID-19 conspiracy theorists Central South University alumni 1980s births Living people Year of birth uncertain People from Qingdao Scientists from Shandong Chinese emigrants to the United States