Lester Skaggs
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Lester Skaggs, Ph.D. (21 November 1911 – 3 April 2009) was a pioneer in the field of medical physics and radiation therapy, a teacher, and innovator.


Life and Times

Skaggs was born on 21 November 1911 in
Trenton, Missouri Trenton is a city in Grundy County, Missouri, Grundy County, Missouri, United States. The population was 5,609 at the 2020 United States census, 2020 census. It is the county seat of Grundy County. The city used to be the world's largest producer ...
. He grew up on a farm in northern Missouri. He attended a one-room schoolhouse and to get to high school, he had to ride a horse. Skaggs was the oldest of three children and his father planned for Skaggs to become a farmer. Instead, Skaggs had other interests and found amazement with tinkering, and enjoyed designing and building contraptions and made plans for a science career. He attended the
University of Missouri The University of Missouri (Mizzou or MU) is a public university, public Land-grant university, land-grant research university in Columbia, Missouri, United States. It is Missouri's largest university and the flagship of the four-campus Univers ...
and completed a B.S. in
chemistry Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules a ...
with a minor in
mathematics Mathematics is a field of study that discovers and organizes methods, Mathematical theory, theories and theorems that are developed and Mathematical proof, proved for the needs of empirical sciences and mathematics itself. There are many ar ...
in 1933 and M.S. in
physics Physics is the scientific study of matter, its Elementary particle, fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge whi ...
in 1934.Jensen, Trevor. (17 April 2009). Dr. Lester Skaggs 1911-2009: Physicist and U. of C. professor. Chicago Tribune. Chicago, Illinois. He moved to
Chicago Chicago is the List of municipalities in Illinois, most populous city in the U.S. state of Illinois and in the Midwestern United States. With a population of 2,746,388, as of the 2020 United States census, 2020 census, it is the List of Unite ...
in 1935, entered the
University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...
and was accepted into the graduate program in
nuclear physics Nuclear physics is the field of physics that studies atomic nuclei and their constituents and interactions, in addition to the study of other forms of nuclear matter. Nuclear physics should not be confused with atomic physics, which studies th ...
. In 1939, Skaggs was awarded a Ph.D. in nuclear physics. At the University of Chicago, Skaggs had a post-doctoral fellowship in nuclear physics and secured part-time work at the Tumor Clinic at
Michael Reese Hospital Michael Reese Hospital and Medical Center was an American hospital located in the Bronzeville neighborhood of Chicago, Illinois. Founded in 1881, Michael Reese Hospital was a major research and teaching hospital and one of the oldest and largest ...
in
radiation oncology Radiation therapy or radiotherapy (RT, RTx, or XRT) is a treatment using ionizing radiation, generally provided as part of cancer therapy to either kill or control the growth of malignant cells. It is normally delivered by a linear particle a ...
. From 1941 – 1943, the
war effort War effort is a coordinated mobilization of society's resources—both industrial and civilian—towards the support of a military force, particular during a state of war. Depending on the militarization of the culture, the relative si ...
took him to
Washington, D.C. Washington, D.C., formally the District of Columbia and commonly known as Washington or D.C., is the capital city and federal district of the United States. The city is on the Potomac River, across from Virginia, and shares land borders with ...
where he served at the
Carnegie Institution of Washington The Carnegie Institution for Science, also known as Carnegie Science and the Carnegie Institution of Washington, is an organization established to fund and perform scientific research in the United States. This institution is headquartered in W ...
in the Department of Terrestrial Magnetism. Skaggs worked with
physicist A physicist is a scientist who specializes in the field of physics, which encompasses the interactions of matter and energy at all length and time scales in the physical universe. Physicists generally are interested in the root or ultimate cau ...
Nicholas Smith to design an airplane proximity detection system that utilized
radio waves Radio waves (formerly called Hertzian waves) are a type of electromagnetic radiation with the lowest frequencies and the longest wavelengths in the electromagnetic spectrum, typically with frequencies below 300 gigahertz (GHz) and wavelengths ...
to locate and detonate
anti-aircraft Anti-aircraft warfare (AAW) is the counter to aerial warfare and includes "all measures designed to nullify or reduce the effectiveness of hostile air action".AAP-6 It encompasses surface-based, subsurface ( submarine-launched), and air-ba ...
shells.


Manhattan Project

In 1943, he was sent to the
Manhattan Project The Manhattan Project was a research and development program undertaken during World War II to produce the first nuclear weapons. It was led by the United States in collaboration with the United Kingdom and Canada. From 1942 to 1946, the ...
at
Los Alamos, New Mexico Los Alamos (, meaning ''The Poplars'') is a census-designated place in Los Alamos County, New Mexico, United States, that is recognized as one of the development and creation places of the Nuclear weapon, atomic bomb—the primary objective of ...
, working under
Robert Oppenheimer J. Robert Oppenheimer (born Julius Robert Oppenheimer ; April 22, 1904 – February 18, 1967) was an American theoretical physicist who served as the director of the Manhattan Project's Los Alamos Laboratory during World War II. He is often ...
to develop the
atomic bomb A nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either fission (fission or atomic bomb) or a combination of fission and fusion reactions (thermonuclear weapon), producing a nuclear expl ...
. At Los Alamos, Skaggs was charged with the task of adapting the anti-aircraft detection system into a failsafe "fuse" for the first bomb that would be used against
Japan Japan is an island country in East Asia. Located in the Pacific Ocean off the northeast coast of the Asia, Asian mainland, it is bordered on the west by the Sea of Japan and extends from the Sea of Okhotsk in the north to the East China Sea ...
. From a distance of 20 miles, Skaggs witnessed the first test at
Alamogordo, New Mexico Alamogordo () is a city in and the county seat of Otero County, New Mexico, United States. A city in the Tularosa Basin of the Chihuahuan Desert, it is bordered on the east by the Sacramento Mountains and to the west by Holloman Air Force ...
. Skaggs immediately understood that the current plans left an unacceptable amount of time for the bombardiers to safely escape from the
drop zone A drop zone (DZ) is a place where parachutists or parachuted supplies land. It can be an area targeted for landing by paratroopers and airborne forces, or a base from which recreational parachutists and skydivers take off in aircraft and land ...
. He developed a system with two back-up systems that allowed additional time to for the plane and crew to make a secure exit from the skies over Japan.


Michael Reese Hospital

When
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
ended Skaggs returned home to
Chicago Chicago is the List of municipalities in Illinois, most populous city in the U.S. state of Illinois and in the Midwestern United States. With a population of 2,746,388, as of the 2020 United States census, 2020 census, it is the List of Unite ...
and went back to work on the medical applications of
radiation In physics, radiation is the emission or transmission of energy in the form of waves or particles through space or a material medium. This includes: * ''electromagnetic radiation'' consisting of photons, such as radio waves, microwaves, infr ...
. He resumed his work at
Michael Reese Hospital Michael Reese Hospital and Medical Center was an American hospital located in the Bronzeville neighborhood of Chicago, Illinois. Founded in 1881, Michael Reese Hospital was a major research and teaching hospital and one of the oldest and largest ...
and went on assignment to the physics department at the
University of Illinois The University of Illinois Urbana-Champaign (UIUC, U of I, Illinois, or University of Illinois) is a public university, public land-grant university, land-grant research university in the Champaign–Urbana metropolitan area, Illinois, United ...
to team with
Donald Kerst Donald William Kerst (November 1, 1911 – August 19, 1993) was an American physicist who worked on advanced particle accelerator concepts (accelerator physics) and plasma physics. He is most notable for his development of the betatron, a novel ...
for a
physics Physics is the scientific study of matter, its Elementary particle, fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge whi ...
research project. This began what was to become a classic case of collaborative work between two individuals. The goal was to utilize a
Betatron A betatron is a type of cyclic particle accelerator for electrons. It consists of a torus-shaped vacuum chamber with an electron source. Circling the torus is an iron transformer core with a wire winding around it. The device functions simil ...
to extract an
electron beam Since the mid-20th century, electron-beam technology has provided the basis for a variety of novel and specialized applications in semiconductor manufacturing, microelectromechanical systems, nanoelectromechanical systems, and microscopy. Mechani ...
for medical use. The betatron was invented by Kerst for physics experiments. As serendipity often plays a role in
medical Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
and
scientific Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which stu ...
developments, sometimes accompanied by a dose of irony, chance presented a member of the team, who was a promising physics graduate student. The student was diagnosed with a
brain tumor A brain tumor (sometimes referred to as brain cancer) occurs when a group of cells within the Human brain, brain turn cancerous and grow out of control, creating a mass. There are two main types of tumors: malignant (cancerous) tumors and benign ...
, glioblastoma multiformae and no current treatment options available for the tumor. The first clinical use of the high energy Betatron radiation for
medical therapy A therapy or medical treatment is the attempted remediation of a health problem, usually following a medical diagnosis. Both words, ''treatment'' and ''therapy'', are often abbreviated tx, Tx, or Tx. As a rule, each therapy has indications an ...
proved beneficial to effectively reduce the mass of the tumor, yet not sufficient to eliminate the tumor and provide a cure.Kuchnir, Franca T. (27 April 2013). Medical Physics before the Millennium, A Personal Experience. Ideals.illinois.edu.


University of Chicago

In 1948, Skaggs accepted a faculty appointment as assistant professor of radiology at the University of Chicago. In 1949, he took the promotion to associate professor with the responsibility for the development of radiation therapy equipment and facilities at Argonne Cancer Research Hospital (ACRH). The Atomic Energy Commission program, titled "
Atoms for Peace "Atoms for Peace" was the title of a speech delivered by U.S. president Dwight D. Eisenhower to the UN General Assembly in New York City on December 8, 1953. The United States then launched an "Atoms for Peace" program that supplied equipment ...
" funded the facilities at ACRH. In 1953, the ACRH was among the initial list of hospitals dedicated to
radiation therapy Radiation therapy or radiotherapy (RT, RTx, or XRT) is a therapy, treatment using ionizing radiation, generally provided as part of treatment of cancer, cancer therapy to either kill or control the growth of malignancy, malignant cell (biology), ...
for
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
treatment.Editor. (2010). Dr. Lester Skaggs: 1911-2009. In Memoriam of Lester Skaggs Dose Calculation and Treatment Planning. AbstractID: 14651. American Association of Physicists in Medicine. https://www.aapm.org/meetings/amos2/pdf/49-14651-81498-89.pdf At ACRH, the next project for the Skaggs and Lanzl team was the design of a cobalt treatment unit, that was built for the most part, in the
machine shop A machine shop or engineering workshop is a room, building, or company where machining, a form of subtractive manufacturing, is done. In a machine shop, machinists use machine tools and cutting tool (machining), cutting tools to make parts, usua ...
s of ACRH and the
University of Illinois The University of Illinois Urbana-Champaign (UIUC, U of I, Illinois, or University of Illinois) is a public university, public land-grant university, land-grant research university in the Champaign–Urbana metropolitan area, Illinois, United ...
. The duo of Skaggs and Lanzl began in the 1950s another project. This time the goal was to develop and establish a graduate program in medical physics, perhaps the first in the United States. In the 1960s, a doctorate program was launched that would award a Ph.D. degree in
medical physics Medical physics deals with the application of the concepts and methods of physics to the prevention, diagnosis and treatment of human diseases with a specific goal of improving human health and well-being. Since 2008, medical physics has been incl ...
. In 1956, Skaggs, received a promotion to full
professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other tertiary education, post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin ...
. He designed and built an
analog computer An analog computer or analogue computer is a type of computation machine (computer) that uses physical phenomena such as Electrical network, electrical, Mechanics, mechanical, or Hydraulics, hydraulic quantities behaving according to the math ...
to calculate the
radiation dose Ionizing (ionising) radiation, including nuclear radiation, consists of subatomic particles or electromagnetic waves that have enough energy per individual photon or particle to ionize atoms or molecules by detaching electrons from them. Some pa ...
to tissue to be utilized in treatment plans for
radiation therapy Radiation therapy or radiotherapy (RT, RTx, or XRT) is a therapy, treatment using ionizing radiation, generally provided as part of treatment of cancer, cancer therapy to either kill or control the growth of malignancy, malignant cell (biology), ...
. The ‘computer’ was finally running by 1963 and the components occupied a small room. In the 1970s, Franca T. Kuchnir and Skaggs developed a method to produce neutrons for radiation therapy, maybe the first fast-neutron therapy facility in the United States.Editor, NAL. (6 January 1972). Consider Use of NAL Linac, Booster for Cancer Therapy. The Village Crier. National Accelerator Laboratory. 4(1): 1-2.


References

{{DEFAULTSORT:Skaggs, Lester 1911 births 2009 deaths People from Trenton, Missouri University of Missouri alumni University of Chicago alumni 20th-century American chemists American mathematicians 20th-century American physicists Scientists from Missouri University of Missouri physicists American nuclear physicists Manhattan Project people Los Alamos National Laboratory personnel University of Illinois faculty Argonne National Laboratory people United States Atomic Energy Commission Atoms for Peace Medical physicists Fellows of the American Physical Society