Lei "Stanley" Qi () is an associate professor in the department of bioengineering, and the department of chemical and systems biology at

Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...

. Qi led the development of the first catalytically dead Cas9 lacking endonuclease activity (dCas9), which is the basis for

CRISPR interference CRISPR interference (CRISPRi) is a genetic perturbation technique that allows for sequence-specific repression of gene expression in prokaryotic and eukaryotic cells. It was first developed by Stanley Qi and colleagues in the laboratories of Wend ...

(CRISPRi). His laboratory subsequently developed CRISPR-Genome Organization (CRISPR-GO) based on dCas9 and CRISPR-Transcriptome Organization (CRISPR-TO) based on dCas13. Qi is a co-inventor of the

University of California The University of California (UC) is a public university, public Land-grant university, land-grant research university, research university system in the U.S. state of California. Headquartered in Oakland, California, Oakland, the system is co ...

patent on the CRISPR gene-editing technology.

Early life and education

Qi obtained his B.S. in physics and math from

Tsinghua University Tsinghua University (THU) is a public university in Haidian, Beijing, China. It is affiliated with and funded by the Ministry of Education of China. The university is part of Project 211, Project 985, and the Double First-Class Constructio ...

, China, Master in physics from

UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a public land-grant research university in Berkeley, California, United States. Founded in 1868 and named after the Anglo-Irish philosopher George Berkele ...

, and PhD in bioengineering from UC Berkeley. During his PhD work at Berkeley, he studied synthetic biology with Adam Arkin, and was the first to explore engineering the CRISPR for targeted gene editing and gene regulation with

Jennifer Doudna Jennifer Anne Doudna (; born February 19, 1964) is an American biochemist who has pioneered work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. She received the 2020 Nobel Prize in Chemistry, wit ...

. After PhD, he performed independent research work as a faculty fellow at UCSF. He joined the Stanford faculty in 2014.

Award

Qi has won awards, including NIH Director's Early Independence Award, Pew Biomedical Scholar, and Alfred. P. Sloan Fellowship.

References

External links

Qi Lab in Stanford

Qi Lab in UCSF
{{DEFAULTSORT:Qi, Lei Stanley 1983 births Living people American bioengineers Chinese bioengineers Tsinghua University alumni University of California, Berkeley alumni Stanford University faculty Synthetic biologists American biochemists Chinese biochemists People from Weifang Chemists from Shandong Educators from Shandong Biologists from Shandong Chinese emigrants to the United States Sloan Research Fellows University of California, San Francisco faculty