Lecidella Carpathica
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''Lecidella carpathica'' is a species of
crustose lichen Crustose lichens are lichens that form a crust which strongly adheres to the Substrate (biology), substrate (soil, rock, tree bark, etc.), making separation from the substrate impossible without destruction. The basic structure of crustose lichen ...
in the family
Lecanoraceae The Lecanoraceae are a family of lichen A lichen ( , ) is a hybrid colony (biology), colony of algae or cyanobacteria living symbiotically among hypha, filaments of multiple fungus species, along with yeasts and bacteria embedded in the c ...
. It was
formally described A species description is a formal scientific description of a newly encountered species, typically articulated through a scientific publication. Its purpose is to provide a clear description of a new species of organism and explain how it differ ...
as a new species in 1861 by the German lichenologist
Gustav Wilhelm Körber Gustav Wilhelm Körber (10 January 1817, Jelenia Góra, Hirschberg – 27 January 1885, Breslau) was a Silesian-German lichenologist and a professor at the University of Wrocław, University of Breslau. He specialized in the flora of Central Europ ...
. Three
secondary metabolite Secondary metabolites, also called ''specialised metabolites'', ''secondary products'', or ''natural products'', are organic compounds produced by any lifeform, e.g. bacteria, archaea, fungi, animals, or plants, which are not directly involved ...
s that occur in this species, hopane-6α,22-diol, brialmontin, and
atraric acid Atraric acid is a naturally occurring phenolic compound and ester with the IUPAC name methyl 2,4-dihydroxy-3,6-dimethylbenzoate and molecular formula C10H12O4. It occurs in the root-bark of '' Pygeum africanum'' and '' Evernia prunastri'' (Oakmoss ...
,
inhibit Inhibitor or inhibition may refer to: Biology * Enzyme inhibitor, a substance that binds to an enzyme and decreases the enzyme's activity * Reuptake inhibitor, a substance that increases neurotransmission by blocking the reuptake of a neurotransmi ...
the enzyme
protein tyrosine phosphatase 1B Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the founding member of the protein tyrosine phosphatase (PTP) family. In humans it is encoded by the ''PTPN1'' gene. PTP1B ...
. This enzyme is a therapeutic target for
diabetes Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...
treatments and plays a major role in negative regulation of the
insulin signaling pathway Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main anabolic hormone of the body. It regulates the metabolism of carb ...
.


References

{{Taxonbar, from=Q15016954 Lecanoraceae Lichen species Lichens described in 1861 Taxa named by Gustav Wilhelm Körber