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Laurent Levy (born 1971) is a
French French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ...
physical chemist Physical chemistry is the study of macroscopic and microscopic phenomena in chemical systems in terms of the principles, practices, and concepts of physics such as motion, energy, force, time, thermodynamics, quantum chemistry, statistical mech ...
,
inventor An invention is a unique or novel device, method, composition, idea or process. An invention may be an improvement upon a machine, product, or process for increasing efficiency or lowering cost. It may also be an entirely new concept. If an id ...
, and pioneer of
nanotechnology Nanotechnology, also shortened to nanotech, is the use of matter on an atomic, molecular, and supramolecular scale for industrial purposes. The earliest, widespread description of nanotechnology referred to the particular technological goal o ...
and
nanomedicine Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotec ...
. He is the co-founder of the global biotechnology company
Nanobiotix Nanobiotix is a biotechnology company that uses nanomedicine to develop new radiotherapy techniques for cancer patients. The company is headquartered in Paris, with additional corporate offices in New York and Massachusetts. History Nanobiotix is ...
, and has served as
chief executive officer A chief executive officer (CEO), also known as a central executive officer (CEO), chief administrator officer (CAO) or just chief executive (CE), is one of a number of corporate executives charged with the management of an organization especial ...
(CEO) since its inception in March 2003. He also authored more than 35 international scientific publications and has applied for several patents.


Early life and education

Laurent Levy was born on the outskirts of northern-east
Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. ...
,
France France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of overseas regions and territories in the Americas and the Atlantic, Pacific and Indian Oceans. Its metropolitan ar ...
, in Montreuil. After high school, Laurent went on to study biology at Pierre and Marie Curie University (Paris VI). He changed his area of study to
biophysics Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. ...
then to physics and chemistry after two years, graduating with his bachelor's degree in 1994. He then earned his master's degree (DEA) in physics of condensed matter from UPVI-ESPCI. Laurent attended Paris VI and the CEA for doctoral studies in physical chemistry, specializing in nanomaterials. His doctoral thesis centered on quantum confinement as it relates to magnetic semiconductors. Following the receipt of his doctorate, Levy completed a postdoctoral fellowship with Prof.
Paras N. Prasad Paras Nath Prasad (born in 1946) is an Indian chemist. He is the SUNY Distinguished Professor at the University at Buffalo and holds a tenured faculty appointment in the department of Chemistry. In addition, he also holds non-tenured appointment ...
at the Institute for Lasers, Photonics, and Biophotonics at
SUNY Buffalo The State University of New York at Buffalo, commonly called the University at Buffalo (UB) and sometimes called SUNY Buffalo, is a public research university with campuses in Buffalo and Amherst, New York. The university was founded in 1846 ...
in the United States.


Work

In 2003, Levy founded Nanobiotix to create a medical treatment using the techniques he developed at SUNY Buffalo. Nanobiotix would build on his work to develop what is now known as NBTXR3, a first-in-class “radioenhancer” designed to significantly increase the efficacy of
radiation therapy Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Rad ...
without increasing negative
side effects In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequence ...
associated with
radiation In physics, radiation is the emission or transmission of energy in the form of waves or particles through space or through a material medium. This includes: * ''electromagnetic radiation'', such as radio waves, microwaves, infrared, vi ...
. In 2011, Nanobiotix treated its first patient using NBTXR3. In 2018 the results of a phase III clinical trial established that this new type of product could work in humans. In 2019 the company received approval to sell NBTXR3 in Europe under the brand name Hensify® for the treatment of soft tissue sarcomas of the extremities and trunk wall. In 2015 Levy joined the board of biotech
startup A startup or start-up is a company or project undertaken by an entrepreneur to seek, develop, and validate a scalable business model. While entrepreneurship refers to all new businesses, including self-employment and businesses that never intend t ...
Valbiotis, the first company to register a
nutraceutical A nutraceutical or bioceutical is a pharmaceutical alternative which claims physiological benefits. In the US, "nutraceuticals" are largely unregulated, as they exist in the same category as dietary supplements and food additives by the FDA, unde ...
based on clinical findings. The company develops nutraceutical products for the prevention of
diabetes Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level (hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ...
in pre-diabetics. Levy helped take Valbiotis public in 2018. In 2019, Levy co-founded the biotechnology company Curadigm as a spin-off from Nanobiotix. Curadigm's lead technology is a nanoprimer that affects
liver The liver is a major organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it ...
function, reducing its ability to filter out drugs, making drug delivery more efficacious.


European nanomedicine advocacy

As Nanobiotix grew, Levy became increasingly frustrated at the struggles nanomedicine companies faced in gaining visibility and support in the
European Union The European Union (EU) is a supranational political and economic union of member states that are located primarily in Europe. The union has a total area of and an estimated total population of about 447million. The EU has often been ...
. To advocate for nanomedical development, Levy joined the
European Technology Platform Nanomedicine The European Technology Platform on Nanomedicine (ETP Nanomedicine) is a European Technology Platform initiative to improve the competitive situation of the European Union in the field of nanomedicine, the application of nanotechnology to medicine. ...
(ETPN) in 2012 and was elected Vice President. Levy is a founding member of the ETPN Translation Advisory Board, which has supported 109 European biotech entrepreneurs in launching their companies. Levy also helped to establish the ETPN's Nanomedicine Translation Hub, which advises
SMEs Superconducting magnetic energy storage (SMES) systems store energy in the magnetic field created by the flow of direct current in a superconducting coil which has been cryogenically cooled to a temperature below its superconducting critical t ...
, Startups, Academics and Inventors on how to bring their nanomedicine projects to the market.


Awards and recognition

* 2019 Prix Galien * 2018 ** CPhI Pharma Award - Excellence in Pharma: CEO of the year Laurent Levy ** CPhI Pharma Award - Pharma Company of the year : Nanobiotix **European Business Award 2018 : The award for Innovation * 2016 European Mediscience Award: Best technology Award * 2015 Prix de la relation actionnaires * 2013 University of Buffalo Young Entrepreneurs Prize : Laurent Levy * 2006 Paris Bio Prize * 2003 Inventor of the year: Niagara frontier intellectual property law association


External links


Ted Talk


Patents


NANOBIOTIX CORE TECHNOLOGYACTIVATABLE PARTICLESNANOPARTICLE DELIVERY SYSTEMS, PREPARATION AND USES THEREOFNANOPARTICLES COMPRISING METALLIC AND HAFNIUM OXIDE MATERIALS, PREPARATION AND USES THEREOF

INORGANIC NANOPARTICLES COMPOSITIONS IN COMBINATION WITH IONIZING RADIATIONS FOR TREATING CANCERCOMPOSITIONS AND METHODS FOR USE IN MEDICAL DIAGNOSISCOMPOSITIONS AND METHODS FOR USE IN ONCOLOGYPHARMACEUTICAL COMPOSITION COMPRISING NANOPARTICLES, PREPARATION AND USES THEREOFNANOPARTICLES FOR USE AS A THERAPEUTIC VACCINEMETALLIC NANOPARTICLES, PREPARATION AND USES THEREOFWO/2014/191569: PHARMACEUTICAL COMPOSITION, PREPARATION AND USES THEREOFPHARMACEUTICAL COMPOSITION COMBINING AT LEAST TWO DISTINCT NANOPARTICLES AND A PHARMACEUTICAL COMPOUND, PREPARATION AND USES THEREOFNANOPARTICLES FOR USE FOR TREATING A NEURONAL DISORDERNANOPARTICLES FOR USE FOR ENHANCING BRAIN PERFORMANCES OR FOR TREATING STRESSCOATED NANOPARTICLES FOR USE FOR MODULATING ELECTRICAL POLARIZATION OF NEURONSNANOPARTICLES FOR USE FOR TREATING A NEURONAL DISORDER


Publications

* * *


References

{{DEFAULTSORT:Levy, Laurent French physical chemists Pierre and Marie Curie University alumni French chief executives French healthcare chief executives French nanotechnologists 1971 births Living people University at Buffalo alumni