Laserphyrin
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Talaporfin (
INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway. Before the advent of motorized transportation, they also provided accomm ...
, also known as aspartyl chlorin, mono-L-aspartyl chlorin e6, NPe6, or LS11) is a
chlorin In organic chemistry, chlorins are tetrapyrrole pigments that are partially hydrogenation, hydrogenated porphyrins. The parent chlorin is an unstable compound which undergoes air oxidation to porphine. The name chlorin derives from chlorophyll. ...
based
photosensitizer Photosensitizers are light absorbers that alter the course of a photochemical reaction. They usually are catalysts. They can function by many mechanisms; sometimes they abstract an electron from the substrate, and sometimes they abstract a hydro ...
used in
photodynamic therapy Photodynamic therapy (PDT) is a form of phototherapy involving light and a photosensitizing chemical substance used in conjunction with molecular oxygen to elicit cell death ( phototoxicity). PDT is used in treating acne, wet age-related macula ...
(PDT). It absorbs red light at 664-667 nm normally provided by a laser tuned to this wavelength. It was approved in Japan (in 2004) for PDT of lung cancer and marketed as Laserphyrin.


References

{{Chemotherapeutic agents
Extracorporeal Photo-Immunotherapy for Circulating Tumor Cells
Photosensitizing agents Tetrapyrroles