Laminin subunit alpha-1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''LAMA1''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Interactions
Laminin, alpha 1 has been shown to
interact with
FBLN2
Fibulin-2 is a protein that in humans is encoded by the ''FBLN2'' gene.
This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role dur ...
.
Role in pathology
Mutations of the LAMA1 gene cause the
Poretti–Boltshauser syndrome.
References
Further reading
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{{gene-18-stub
Laminins