Kurt Benirschke (May 26, 1924 – September 10, 2018) was a
German-American
German Americans (, ) are Americans who have full or partial German ancestry.
According to the United States Census Bureau's figures from 2022, German Americans make up roughly 41 million people in the US, which is approximately 12% of the pop ...
pathologist
Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
,
geneticist
A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic process ...
and expert on the
placenta
The placenta (: placentas or placentae) is a temporary embryonic and later fetal organ that begins developing from the blastocyst shortly after implantation. It plays critical roles in facilitating nutrient, gas, and waste exchange between ...
and
reproduction
Reproduction (or procreation or breeding) is the biological process by which new individual organisms – "offspring" – are produced from their "parent" or parents. There are two forms of reproduction: Asexual reproduction, asexual and Sexual ...
in humans and myriad mammalian species. At the
San Diego Zoo
The San Diego Zoo is a zoo in San Diego, California, United States, located in Balboa Park (San Diego), Balboa Park. It began with a collection of animals left over from the 1915 Panama–California Exposition that were brought together by its ...
, he created the world's first
frozen zoo
A frozen zoo is a storage facility in which genetic materials taken from animals (e.g. DNA, sperm, eggs, embryos and live tissue) are stored at very low temperatures (−196 °C) in tanks of liquid nitrogen. Material preserved in this way ca ...
for the cryopreservation of genetic material from endangered species.
Early life and education
Benirschke grew up in
Glückstadt
Glückstadt (; ) is a town in the Steinburg district of Schleswig-Holstein, Germany. It is located on the right bank of the Lower Elbe at the confluence of the small Rhin river, about northwest of Altona. Glückstadt is part of the Hamburg ...
, a small town in northern Germany. He received his M.D. degree from the
University of Hamburg
The University of Hamburg (, also referred to as UHH) is a public university, public research university in Hamburg, Germany. It was founded on 28 March 1919 by combining the previous General Lecture System ('':de:Allgemeines Vorlesungswesen, ...
in 1948. He immigrated to the United States in 1949.
Career
After an internship in
New Jersey
New Jersey is a U.S. state, state located in both the Mid-Atlantic States, Mid-Atlantic and Northeastern United States, Northeastern regions of the United States. Located at the geographic hub of the urban area, heavily urbanized Northeas ...
, he trained in pathology at university hospitals affiliated with
Harvard Medical School
Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
in
Boston
Boston is the capital and most populous city in the Commonwealth (U.S. state), Commonwealth of Massachusetts in the United States. The city serves as the cultural and Financial centre, financial center of New England, a region of the Northeas ...
. In 1955, he became pathologist of the Boston Lying-in Hospital, now part of the
Brigham and Women's Hospital
Brigham and Women's Hospital (BWH or The Brigham) is a teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two ...
, and there developed his interest in the placenta and reproductive problems.
From 1960 to 1970 he was the chairman of the department of pathology at
Dartmouth Medical School
The Geisel School of Medicine is the medical school of Dartmouth College located in Hanover, New Hampshire. The fourth oldest medical school in the United States, it was founded in 1797 by New England physician Nathan Smith. It is one of the sev ...
in
Hanover, New Hampshire
Hanover is a New England town, town located along the Connecticut River in Grafton County, New Hampshire, United States. As of the 2020 United States census, 2020 census, its population was 11,870. The town is home to the Ivy League university ...
, and pursued his interests in placental pathology and comparative reproductive pathology. There, he developed a passion for comparative cytogenetics, discovering the reason for the
sterility of
mule
The mule is a domestic equine hybrid between a donkey, and a horse. It is the offspring of a male donkey (a jack) and a female horse (a mare). The horse and the donkey are different species, with different numbers of chromosomes; of the two ...
s and investigating
twin
Twins are two offspring produced by the same pregnancy.MedicineNet > Definition of Twin Last Editorial Review: 19 June 2000 Twins can be either ''monozygotic'' ('identical'), meaning that they develop from one zygote, which splits and forms two ...
ning in
armadillo
Armadillos () are New World placental mammals in the order (biology), order Cingulata. They form part of the superorder Xenarthra, along with the anteaters and sloths. 21 extant species of armadillo have been described, some of which are dis ...
s and
marmoset
The marmosets (), also known as zaris or sagoin, are twenty-two New World monkey species of the genera '' Callithrix'', '' Cebuella'', '' Callibella'', and ''Mico''. All four genera are part of the biological family Callitrichidae. The term ...
s.
In 1970, Benirschke moved west to participate in the development of a new medical school of the
University of California, San Diego
The University of California, San Diego (UC San Diego in communications material, formerly and colloquially UCSD) is a public university, public Land-grant university, land-grant research university in San Diego, California, United States. Es ...
(UCSD). He established a genetics laboratory and ran the
autopsy
An autopsy (also referred to as post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of deat ...
service at UCSD. He also chaired the department of pathology for two years.
In 1976, Benirschke persuaded the Board of Trustees of the
San Diego Zoo
The San Diego Zoo is a zoo in San Diego, California, United States, located in Balboa Park (San Diego), Balboa Park. It began with a collection of animals left over from the 1915 Panama–California Exposition that were brought together by its ...
to establish a formal research department. Benirschke led this new research department, which was named the Center for the Reproduction of Endangered Species, until 1987 when he became a member of the Zoo's Board of Trustees. He set up a laboratory at the Zoo to study the
chromosome
A chromosome is a package of DNA containing part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells, the most import ...
s of
mammal
A mammal () is a vertebrate animal of the Class (biology), class Mammalia (). Mammals are characterised by the presence of milk-producing mammary glands for feeding their young, a broad neocortex region of the brain, fur or hair, and three ...
s, particularly aspects relating to reproduction and evolution. In collaboration with
T.C. Hsu, he published an ''Atlas of Mammalian Chromosomes'' which presented the
karyotype
A karyotype is the general appearance of the complete set of chromosomes in the cells of a species or in an individual organism, mainly including their sizes, numbers, and shapes. Karyotyping is the process by which a karyotype is discerned by de ...
s of 400 different species of mammals.
He established at the Zoo a collection of frozen cells and reproductive material from dozens of highly endangered species that became famous as the first "
Frozen Zoo
A frozen zoo is a storage facility in which genetic materials taken from animals (e.g. DNA, sperm, eggs, embryos and live tissue) are stored at very low temperatures (−196 °C) in tanks of liquid nitrogen. Material preserved in this way ca ...
". In the 1970s when he began this collection, there was no technology available to make use of it, but he quoted
Daniel Boorstin
Daniel Joseph Boorstin (October 1, 1914 – February 28, 2004) was an American historian at the University of Chicago who wrote on many topics in American and world history. He was appointed the twelfth Librarian of the United States Congress in ...
: "You must collect things for reasons you don't yet understand." The Frozen Zoo eventually became a priceless genetic resource.
Throughout his career, he moved freely back and forth between human medicine and animal medicine. This inspired the title ''One Medicine'' given to a
Festschrift
In academia, a ''Festschrift'' (; plural, ''Festschriften'' ) is a book honoring a respected person, especially an academic, and presented during their lifetime. It generally takes the form of an edited volume, containing contributions from the h ...
written by 50 of his colleagues to honor his 60th birthday. In the introduction, O. A. Ryder and M. L. Byrd state, "The acknowledgment that the underlying mechanisms of cellular function and organismal development are highly similar among animals provides the impetus for the title of this volume, ''One Medicine''. It is a tribute to Prof. Kurt Benirschke from his students and colleagues. As such, we attempt to recognize the breadth and depth of his thinking and to acknowledge the significant role he has played in aspects of human medicine, veterinary medicine, and wildlife conservation."
In 1994, he was elected a fellow of the
American Academy of Arts and Sciences
The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
.
The same year, he retired from the faculty at UCSD. From 1997-2000 he was president of the Zoo's Board of Trustees and looked after the "Proyecto Tagua" in
Paraguay
Paraguay, officially the Republic of Paraguay, is a landlocked country in South America. It is bordered by Argentina to the Argentina–Paraguay border, south and southwest, Brazil to the Brazil–Paraguay border, east and northeast, and Boli ...
, a breeding facility of the newly discovered species of
peccary
Peccaries (also javelinas or skunk pigs) are pig-like ungulates of the family Tayassuidae (New World pigs). They are found throughout Central and South America, Trinidad in the Caribbean, and in the southwestern area of North America. Peccari ...
. His text (with Peter Kaufmann) on ''Human Placental Pathology'' is the standard text on the subject. In 2008 he was one of the founders of the
Center for Academic Research and Training in Anthropogeny
The Center for Academic Research and Training in Anthropogeny (CARTA) is a center at the University of California, San Diego (UC San Diego). Formally established in 2008, CARTA is a collaboration between faculty members of UC San Diego main camp ...
(CARTA), an interdisciplinary research group based at UCSD and devoted to the study of human origins.
Benirschke was a member of many societies and authored 30 books and 510 scientific publications. He was described as a "visionary" and a "Renaissance physician".
Personal life
He met his wife Marion, a nurse, during his internship. They were married for 66 years at the time of his death and had three children, two sons and a daughter. One son, Dr. Stephen Benirschke, lives in Seattle and is a foot and ankle
orthopedic surgeon
Orthopedic surgery or orthopedics (American and British English spelling differences, alternative spelling orthopaedics) is the branch of surgery concerned with conditions involving the musculoskeletal system. Orthopedic surgeons use both surgic ...
best known for his specialty with the calcaneus fracture surgery. His other son,
Rolf Benirschke
Rolf Joachim Benirschke (born February 7, 1955) is an American former professional football player who was a placekicker in the National Football League (NFL). He played for the San Diego Chargers from 1977 until 1986. He is probably most kno ...
, is a retired placekicker for the
San Diego Chargers
The San Diego Chargers were a professional American football team in the National Football League (NFL). The Chargers played in San Diego, California from 1961 until 2016, before relocating back to the Greater Los Angeles area, where the franch ...
of the
National Football League
The National Football League (NFL) is a Professional gridiron football, professional American football league in the United States. Composed of 32 teams, it is divided equally between the American Football Conference (AFC) and the National ...
. His daughter Ingrid Benirschke-Perkins is the community relations director for CARTA.
References
External links
About Kurt Benirschkefrom the site devoted to ''Comparative Placentation'', a volume on animal placentas
by Paul Popescu for the European Cytogeneticists Association
selection of Kurt Benirschke as Father of the Year by San Diego Online
{{DEFAULTSORT:Benirschke, Kurt
1924 births
2018 deaths
American geneticists
American pathologists
American zoologists
Physicians from California
Geisel School of Medicine faculty
Fellows of the American Academy of Arts and Sciences
Emigrants from West Germany to the United States
Harvard Medical School people
University of California, San Diego faculty
People from Glückstadt