Konstantin Alexandrovich Efetov
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Konstantin Aleksandrovich Efetov (; ; born 18 July 1958) is a Ukrainian
biologist A biologist is a scientist who conducts research in biology. Biologists are interested in studying life on Earth, whether it is an individual Cell (biology), cell, a multicellular organism, or a Community (ecology), community of Biological inter ...
and
biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...
, Honored Scientist of Ukraine, Academician of the Russian Academy of Natural History, Professor, Dr. Biol. Sci., Head of the Department of Biological Chemistry and Laboratory of Biotechnology of the
Crimea State Medical University The Medical Academy named after S. I. Georgievsky (; ) is the institution of higher medical education situated in Simferopol (Autonomous Republic of Crimea). According to some independent estimations, it is one of the most prominent medical scho ...
.


Biography

Efetov was born in Simferopol on 18 July 1958. In 1975, having graduated from school with Gold Medal, he entered the Crimea Medical Institute and graduated from it magna cum laude (with honours) in 1981. After completion of his postgraduate course, in 1986 he became Philosophy Doctor of Medicine having defended his PhD thesis "Stability of Conformation of Immunoglobulins G at Norm and Chronic Lymphoid Leukaemia" (Efetov's Scientific Adviser was Professor G. V. Troitsky, the Corresponding Member of the Academy of Sciences of Ukraine, the Honored Scientist of Ukraine). In 1986, Efetov was among the founders of the Hybridoma Laboratory at CSMU. Since 1986, he worked as the senior, chief, and then top research scientific researcher at CSMU; since 1992, he has been working as the Head of the Laboratory of Biotechnology. In 1994, he became Doctor of Biological Sciences having defended his doctoral thesis "A Study of Immunoglobulins at Norm and Pathology with Use of Monoclonal Antibodies and Spectral Methods", in which, for the first time, he applied insect
peptide Peptides are short chains of amino acids linked by peptide bonds. A polypeptide is a longer, continuous, unbranched peptide chain. Polypeptides that have a molecular mass of 10,000 Da or more are called proteins. Chains of fewer than twenty am ...
s for investigation of human
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
s. Since 1995, Efetov is Professor and since 1999, he is the Head of the Department of Biological Chemistry of the Crimea State Medical University.


Scientific activities

Efetov's major scientific interests are focused on molecular
immunology Immunology is a branch of biology and medicine that covers the study of Immune system, immune systems in all Organism, organisms. Immunology charts, measures, and contextualizes the Physiology, physiological functioning of the immune system in ...
, evolutionary biology, and
biosystematics Systematics is the study of the diversification of living forms, both past and present, and the relationships among living things through time. Relationships are visualized as evolutionary trees (synonyms: phylogenetic trees, phylogenies). Phyl ...
. Using spectral methods, he has demonstrated the existence of changes in the conformation of human
immunoglobulin An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as pathogenic bacteria, bacteria and viruses, includin ...
s at malignant tumors. He was the first to suggest using the insect proteins and peptides as molecule probes for investigation of the human proteins at norm and pathology. Efetov has established a new scientific approach – monoclonal immunosystematics that makes it possible to evaluate evolutionary relationships between the biological species through studying their proteins with use of
monoclonal antibodies A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a Lineage (evolution), cell lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell. Mon ...
. He has described one subfamily, 7 new genera and 11 subgenera of living organisms, discovered and described 37 new biological speciesThe List of new taxa of the Zygaenidae described by K. A. Efetov and the list of taxa named in honour of K. A. Efetov
(from the site "The gallery of lepidopterists of Russia and adjacent countries", a small zip-archive; in Russian; retrieved on October 14, 2009)
"Science has no boundaries", a report on the CSMU official site
(retrieved on October 14, 2009)
inhabiting
Japan Japan is an island country in East Asia. Located in the Pacific Ocean off the northeast coast of the Asia, Asian mainland, it is bordered on the west by the Sea of Japan and extends from the Sea of Okhotsk in the north to the East China Sea ...
,
Korea Korea is a peninsular region in East Asia consisting of the Korean Peninsula, Jeju Island, and smaller islands. Since the end of World War II in 1945, it has been politically Division of Korea, divided at or near the 38th parallel north, 3 ...
,
Indonesia Indonesia, officially the Republic of Indonesia, is a country in Southeast Asia and Oceania, between the Indian Ocean, Indian and Pacific Ocean, Pacific oceans. Comprising over List of islands of Indonesia, 17,000 islands, including Sumatra, ...
,
China China, officially the People's Republic of China (PRC), is a country in East Asia. With population of China, a population exceeding 1.4 billion, it is the list of countries by population (United Nations), second-most populous country after ...
,
Taiwan Taiwan, officially the Republic of China (ROC), is a country in East Asia. The main geography of Taiwan, island of Taiwan, also known as ''Formosa'', lies between the East China Sea, East and South China Seas in the northwestern Pacific Ocea ...
,
Vietnam Vietnam, officially the Socialist Republic of Vietnam (SRV), is a country at the eastern edge of mainland Southeast Asia, with an area of about and a population of over 100 million, making it the world's List of countries and depende ...
,
Myanmar Myanmar, officially the Republic of the Union of Myanmar; and also referred to as Burma (the official English name until 1989), is a country in northwest Southeast Asia. It is the largest country by area in Mainland Southeast Asia and has ...
(Burma),
New Zealand New Zealand () is an island country in the southwestern Pacific Ocean. It consists of two main landmasses—the North Island () and the South Island ()—and List of islands of New Zealand, over 600 smaller islands. It is the List of isla ...
,
India India, officially the Republic of India, is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area; the List of countries by population (United Nations), most populous country since ...
,
Russia Russia, or the Russian Federation, is a country spanning Eastern Europe and North Asia. It is the list of countries and dependencies by area, largest country in the world, and extends across Time in Russia, eleven time zones, sharing Borders ...
,
Kyrgyzstan Kyrgyzstan, officially the Kyrgyz Republic, is a landlocked country in Central Asia lying in the Tian Shan and Pamir Mountains, Pamir mountain ranges. Bishkek is the Capital city, capital and List of cities in Kyrgyzstan, largest city. Kyrgyz ...
,
Turkmenistan Turkmenistan is a landlocked country in Central Asia bordered by Kazakhstan to the northwest, Uzbekistan to the north, east and northeast, Afghanistan to the southeast, Iran to the south and southwest and the Caspian Sea to the west. Ash ...
,
Afghanistan Afghanistan, officially the Islamic Emirate of Afghanistan, is a landlocked country located at the crossroads of Central Asia and South Asia. It is bordered by Pakistan to the Durand Line, east and south, Iran to the Afghanistan–Iran borde ...
,
Ukraine Ukraine is a country in Eastern Europe. It is the List of European countries by area, second-largest country in Europe after Russia, which Russia–Ukraine border, borders it to the east and northeast. Ukraine also borders Belarus to the nor ...
and
Hungary Hungary is a landlocked country in Central Europe. Spanning much of the Pannonian Basin, Carpathian Basin, it is bordered by Slovakia to the north, Ukraine to the northeast, Romania to the east and southeast, Serbia to the south, Croatia and ...
. Many times the results of his studies have been represented at international congresses and symposia held in different countries of Europe. In 2004, he initiated and hosted the International Symposium "Biology, Phylogeny, Molecular Biology, and Genetics of
Zygaenidae The Zygaenidae moths are a family of Lepidoptera. The majority of zygaenids are tropical, but they are nevertheless quite well represented in temperate regions. Some of the 1000 or so species are commonly known as burnet or forester moths, ofte ...
" at the Crimean State Medical University. He is the author of 665 scientific works that include over 25 monographs and 18 patents for inventions. His studies have been quoted in publications of scientists of 65 countries in 12 languages (including English, Hungarian, Spanish, Italian, German, French, and Japanese). He has trained one Doctor of Science and 5 Philosophy Doctors; currently (2023) he is supervising the writing of 3 dissertations.


Awards and titles

He is the Academician of the Crimean Academy of Science (since 2002), the Honored Scientist of Ukraine (since 2004), the Chairman of the Crimean Biochemical Society (since 2006), the Member of the Central Council of the Ukrainian Biochemical Society (since 2006), the Vice President of the Junior Academy of Science of Crimea (since 1997), the Member of the Council of the European Lepidopterological Society (2005–2009), a Member of the Union of the Russian, Ukrainian and Belarusian Writers of Autonomous Republic of Crimea. For his achievements in the fields of biology and medicine, K. A. Efetov is awarded with four gold medals: "One Thousand Great Scientists" (Great Britain, 2002), "Outstanding Europeans of the 21st Century" (Great Britain, 2003), "International Scientist of the Year" (Great Britain, 2003), "American Medal of Honor" (USA, 2004). He is represented in the biographical reference books "Contemporary Who’s Who" (USA) and "Outstanding Europeans of the 21st Century" (Great Britain). In honour of K. A. Efetov, scientists of Austria, France, Ukraine, and Russia named 3 biological species (''Etroga efetovi'' Richter, 1994; ''Zygaenoprocris efetovi'' Mollet et Tarmann, 2007; ''Chrysartona efetovi'' Parshkova, 2007) and a subgenus of living organisms (''Efetovia'' Mollet, 2001). He is the Laureate of the State Prize of Republic of Crimea (1996), the Laureate of the Prize of the Council of Ministers of Autonomous Republic of Crimea (2000), the Laureate of the Prize of Autonomous Republic of Crimea (2008). He is awarded with the Honorary Diplomas of the Presidium of the Supreme Council of Autonomous Republic of Crimea (1998), the Council of Ministers of Autonomous Republic of Crimea (1998, 2002), and the Ministry of Public Health of Ukraine (1998). He is a member of the editorial boards of the scientific journals "Tavricheskiy Mediko-biologicheskiy Vestnik"The member list of the editorial board and council of CSMU scientific journals
(retrieved on October 15, 2009)
(Ukraine) and "Entomologist’s Gazette" (Great Britain), the scientific Readers "Problems, Achievements and Prospects of Development of Life Sciences and Practical Public Health (Transactions of the Crimean State Medical University)" and "The Marine Doctor’s Bulletin".


Other facts

He has published several books ("A Shocking Secret of the Sistine Chapel", "Das Schockierende Geheimnis der Sixtinischen Kapelle" and "Old Testament’s Secret of the Rib of Adam") and articles (in the journals "Chemistry and Life", "Asclepius", "Discoveries and Hypotheses", "
Kontakto ''Kontakto'' is an Esperanto magazine published by TEJO and supported by the Universal Esperanto Association (UEA). Its 6 annual issues have readers in about 100 countries of the world. It started in 1963 through a proposal of the UEA committee b ...
") devoted to his unusual hypotheses at the crossroads of medicine, art and history. In particular, the author asserts that on
Michelangelo Michelangelo di Lodovico Buonarroti Simoni (6March 147518February 1564), known mononymously as Michelangelo, was an Italian sculptor, painter, architect, and poet of the High Renaissance. Born in the Republic of Florence, his work was inspir ...
’s frescoes in the
Sistine Chapel The Sistine Chapel ( ; ; ) is a chapel in the Apostolic Palace, the pope's official residence in Vatican City. Originally known as the ''Cappella Magna'' ('Great Chapel'), it takes its name from Pope Sixtus IV, who had it built between 1473 and ...
there are several "invisible" images: if examined, they radically change the spectator's ideas about the specific meaning implanted into these frescoes by their creator. Another hypothesis is dedicated to the interpretation of the biblical myth about the creation of woman from Adam's rib: the author sees parallels between the components of this myth and the biochemical mechanism of the formation of female
sex hormones Sex hormones, also known as sex steroids, gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate steroid hormone receptors. The sex hormones include the androgens, estrogens, and progestogens. Their effects a ...
. These hypotheses did obtain wide response in the Internet and even were used for quizzes in the world championship " What? Where? When?". He has published four poetic collections: "Wings’ Stroke", "The Black-and-White Square", "The life of the ‘Bats’" and "The Wells of Memory". He is also the scripter of hymn, the author of flag and the co-author of coat of arms of the
Crimea State Medical University The Medical Academy named after S. I. Georgievsky (; ) is the institution of higher medical education situated in Simferopol (Autonomous Republic of Crimea). According to some independent estimations, it is one of the most prominent medical scho ...
.The CSMU symbols
(retrieved on October 14, 2009)


Books published

* * * * * * * * * * * * * * * * * * *


References


Sources and external links

*

(retrieved October 14, 2009) *
Information about K. A. Efetov on the CSMU official site
(retrieved October 14, 2009) * (written by K. A. Efetov and Yu. I. Budashkin; retrieved October 14, 2009) *

written by K. A. Efetov (from "Crimea: the Book of Records"; retrieved October 14, 2009)
A shocking secret of the Sistine Chapel
written by K. A. Efetov (from the book "Old Testament’s Secret of the Rib of Adam"; retrieved October 14, 2010) {{DEFAULTSORT:Efetov, Konstantin 1958 births Ukrainian lepidopterists Ukrainian biologists Ukrainian chemists Ukrainian biochemists Scientists from Simferopol Living people Soviet lepidopterists Fellows of the American Physical Society