Keratin 9 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''KRT9''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Keratin 9 is a
type I cytokeratin Type I keratins (or Type I cytokeratins) are cytokeratins that constitute the Type I intermediate filaments (IFs) of the intracytoplasmatic cytoskeleton, which is present in all mammalian epithelial cells. Most of the type I keratins consist of acid ...
. It is found only in the
terminally differentiated epidermis
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and Subcutaneous tissue, hypodermis. The epidermal layer provides a barrier to infection from environmental pathogens and regulates the ...
of
palm
Palm most commonly refers to:
* Palm of the hand, the central region of the front of the hand
* Palm plants, of family Arecaceae
** List of Arecaceae genera
**Palm oil
* Several other plants known as "palm"
Palm or Palms may also refer to:
Music ...
s and
soles. Mutations in the gene encoding this protein cause
epidermolytic palmoplantar keratoderma.
References
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Keratins
{{Gene-17-stub