Karen Middleton may refer to:
*
Karen Middleton (journalist)
Karen Middleton is an Australian political journalist in the Canberra Press Gallery covering the Parliament of Australia in Canberra, the national capital of Australia. Until March 2025, Middleton was Political Editor of Guardian Australia.
C ...
, Australian political journalist
*
Karen Middleton (politician) (born 1966), legislator in the U.S. state of Colorado
*
Karen Middleton (basketball), American basketball coach
{{hndis, Middleton, Karen