Julie Angela Segre is the Chief and Senior Investigator of the Translational and Functional Genomics Branch in the

National Human Genome Research Institute The National Human Genome Research Institute (NHGRI) is an institute of the National Institutes of Health, located in Bethesda, Maryland. NHGRI began as the Office of Human Genome Research in The Office of the Director in 1988. This Office transi ...

at the

National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...

. She was elected to the

National Academy of Medicine The National Academy of Medicine (NAM), known as the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Engineerin ...

in 2019, the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...

in 2020 and the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...

in 2022.

Early life and education

Segre was born in

Berkeley, California Berkeley ( ) is a city on the eastern shore of San Francisco Bay in northern Alameda County, California, United States. It is named after the 18th-century Anglo-Irish bishop and philosopher George Berkeley. It borders the cities of Oakland, Cali ...

, the daughter of Bettina "Nina" () and Gino Claudio Segrè. She was raised in

Philadelphia Philadelphia ( ), colloquially referred to as Philly, is the List of municipalities in Pennsylvania, most populous city in the U.S. state of Pennsylvania and the List of United States cities by population, sixth-most populous city in the Unit ...

, where her father was a professor of physics at the University of Pennsylvania. Segre received her B.A. summa cum laude in mathematics from

Amherst College Amherst College ( ) is a Private college, private Liberal arts colleges in the United States, liberal arts college in Amherst, Massachusetts, United States. Founded in 1821 as an attempt to relocate Williams College by its then-president Zepha ...

in 1987, where she later served on the board of trustees. She received her Ph.D. in 1996 from the

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a Private university, private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of moder ...

. Segre then performed postdoctoral training in Molecular Genetics and Cell Biology at the University of Chicago (1996-2000).

Research and career

Segre came to the

of NIH in 2000 and was promoted to a senior investigator with tenure in 2007. Segre's laboratory studies how the

epidermis The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and Subcutaneous tissue, hypodermis. The epidermal layer provides a barrier to infection from environmental pathogens and regulates the ...

interfaces between the body and the environment. Using genomic methodologies, Segre studies the bacteria and microbes of the skin microbiome. Segre's laboratory also develops genomic tools to track hospital-acquired infections of multi-drug resistant organisms.

Medical and research achievements

*2013 received

Service to America Medal The Samuel J. Heyman Service to America Medals, also known as "the Sammies", honor members of the federal government workforce, highlighting the work of employees making significant contributions to the governance of the United States. The awards ...

*2015 elected as a Fellow to the

American Academy of Microbiology American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, p ...

*2019 elected to the National Academy of Medicine *2020 elected to the

*2022 elected to the

*2023 elected as a Fellow to the American Association for the Advancement of Science

References

External links

* * * (Elizabeth O. King Lecture delivered by J. Segre — discussion of 2011 outbreak of

carbapenem Carbapenems are a class of very effective antibiotic agents most commonly used for treatment of severe bacterial infections. This class of antibiotics is usually reserved for known or suspected multidrug-resistant (MDR) bacterial infections. Si ...

-resistant ''

Klebsiella pneumoniae ''Klebsiella pneumoniae'' is a Gram-negative, non-motile, encapsulated, lactose- fermenting, facultative anaerobic, rod-shaped bacterium. It appears as a mucoid lactose fermenter on MacConkey agar. Although found in the normal flora of the mo ...

'') * * {{DEFAULTSORT:Segre, Julie Year of birth missing (living people) Living people American geneticists Amherst College alumni Massachusetts Institute of Technology alumni National Institutes of Health people NIH Women Scientists Project 21st-century American women scientists American women biologists Members of the National Academy of Medicine Fellows of the American Academy of Microbiology Fellows of the American Association for the Advancement of Science American people of Italian-Jewish descent American people of Sephardic-Jewish descent American people of German-Jewish descent American people of German descent People of Tuscan descent People of Lazian descent