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Joseph Lennox Donation Pawan MBE (6 September 1887 – 3 November 1957) was a
Trinidadian Trinidadians and Tobagonians, colloquially known as Trinis or Trinbagonians, are the people who are identified with the country of Trinidad and Tobago. The population of Trinidad is notably diverse, with approximately 35% Indo-Trinidadian, 34% ...
bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology— a subdivision of microbiology that studies bacteria, typically Pathogenic bacteria, pathogenic ones. Bacteriologists are interested in studying and learnin ...
who was the first person to show that
rabies Rabies is a viral disease that causes encephalitis in humans and other mammals. It was historically referred to as hydrophobia ("fear of water") because its victims panic when offered liquids to drink. Early symptoms can include fever and abn ...
could be spread by
vampire bat Vampire bats, members of the subfamily Desmodontinae, are Phyllostomidae, leaf-nosed bats currently found in Central and South America. Their food source is the blood of other animals, a dietary trait called hematophagy. Three extant bat species ...
s to other animals and humans.


Education and career

Born in
Trinidad Trinidad is the larger, more populous island of the Republic of Trinidad and Tobago, the country. The island lies off the northeastern coast of Venezuela and sits on the continental shelf of South America. It is the southernmost island in ...
, Pawan was educated at Saint Mary's College in
Port of Spain Port of Spain ( ; Trinidadian and Tobagonian English, Trinidadian English: ''Port ah Spain'' ) is the capital and chief port of Trinidad and Tobago. With a municipal population of 49,867 (2017), an urban population of 81,142 and a transient dail ...
and won an Island Scholarship in 1907. He then went on to the
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
, where he graduated in 1912 with bachelor's degrees in medicine and surgery. After studying at the
Pasteur Institute The Pasteur Institute (, ) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. Th ...
in
France France, officially the French Republic, is a country located primarily in Western Europe. Overseas France, Its overseas regions and territories include French Guiana in South America, Saint Pierre and Miquelon in the Atlantic Ocean#North Atlan ...
he returned to Trinidad in 1913, first as an Assistant Surgeon at the Colonial Hospital in Port of Spain, and later as the District Medical Officer in
Tobago Tobago, officially the Ward of Tobago, is an List of islands of Trinidad and Tobago, island and Regions and municipalities of Trinidad and Tobago, ward within the Republic of Trinidad and Tobago. It is located northeast of the larger islan ...
and Cedros, in southwestern Trinidad. In 1923 he was appointed as the sole
bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology— a subdivision of microbiology that studies bacteria, typically Pathogenic bacteria, pathogenic ones. Bacteriologists are interested in studying and learnin ...
to the government of
Trinidad and Tobago Trinidad and Tobago, officially the Republic of Trinidad and Tobago, is the southernmost island country in the Caribbean, comprising the main islands of Trinidad and Tobago, along with several List of islands of Trinidad and Tobago, smaller i ...
. In 1925 there was an outbreak of rabies in cattle in Trinidad, which was first diagnosed as
botulism Botulism is a rare and potentially fatal illness caused by botulinum toxin, which is produced by the bacterium ''Clostridium botulinum''. The disease begins with weakness, blurred vision, Fatigue (medical), feeling tired, and trouble speaking. ...
. Humans began contracting rabies in 1929, first diagnosed as
poliomyelitis Poliomyelitis ( ), commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 75% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe ...
. The outbreak continued until 1937, by which time 89 human fatalities were recorded. Pawan found the first infected vampire bat in March 1932. He then soon proved that various species of bat, including fruit-eating bats and particularly the
common vampire bat The common vampire bat (''Desmodus rotundus'') is a small, leaf-nosed bat native to the Americas. It is one of three extant species of vampire bats, the other two being the Hairy-legged vampire bat, hairy-legged and the white-winged vampire bats ...
('' Desmodus rotundus''), with or without artificial infection or the external symptoms of rabies, are capable of transmitting rabies for an extended period of time. "Perhaps, the most heretical disclosure was that vampire bats could recover from the furious stage of the disease and were capable of spreading the disease up to five and one half months." It was later shown that fruit bats of the genus ''
Artibeus The Neotropical fruit bats (''Artibeus'') are a genus of bats within the subfamily Stenodermatinae. The genus consists of 12 species, which are native to Central America, Central and South America, as well as the Caribbean. Description These bat ...
'' demonstrate the same abilities. During this asymptomatic stage the bats continue to behave normally and breed. At first, his basic findings that bats transmitted rabies to people and animals were thought fantastic and ridiculed. Pawan died on 3 November 1957. He was sometimes referred to as John Lennox Pawan by Arthur Greenhall, who was a close friend and associate. It is not certain whether he was ever called "John," or whether the references are misprints.
Dr Pawan’s interests were many and varied. He was the author of numerous papers and studied such subjects as the water supplies of Trinidad; the histology of
Aedes ''Aedes'' (also known as the tiger mosquito) is a genus of mosquitoes originally found in tropical and subtropical zones, but now found on all continents except Antarctica. Some species have been spread by human activity: ''Aedes albopictus'', ...
and Anophole (sic =
Anopheles ''Anopheles'' () is a genus of mosquito first described by the German entomologist Johann Wilhelm Meigen, J. W. Meigen in 1818, and are known as nail mosquitoes and marsh mosquitoes. Many such mosquitoes are Disease vector, vectors of the paras ...
) mosquitos; sickle-cell anaemia; and the mosquito transmission of Venezuelan Equine Encephalomeyelitis Virus in Trinidad. But he will best be remembered in the annals of medical history along with
Louis Pasteur Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist, pharmacist, and microbiologist renowned for his discoveries of the principles of vaccination, Fermentation, microbial fermentation, and pasteurization, the la ...
for his contributions to the study of rabies. His research on bat rabies has been considered by rabies investigators over the world to be a classic of
epidemiological Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent dise ...
studies and has had a profound influence on all subsequent studies up to the present time.


Publications

* 1931, Pawan, J. L. "The Water Supplies of Trinidad and Tobago", ''Journal of Tropical Medicine and Hygiene''. * 1931, Hurst, E. W. and Pawan, J. L. "An Outbreak of Rabies in Trinidad Without history of Bites and with the Symptoms of Acute Ascending Myelitis". ''
The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal, founded in England in 1823. It is one of the world's highest-impact academic journals and also one of the oldest medical journals still in publication. The journal publishes ...
'', 221, 622. * 1932, Hurst, E. W. and Pawan, J. L. "A Further Account of the Trinidad Outbreak of Acute Rabic Myelitis: histology of the experimental disease." ''Jour. Path. Bact.'', 35, 301. * 1936, Pawan, J. L. "Transmission of the Paralytic Rabies in Trinidad of the Vampire Bat: ''Desmodus rotundus murinus'' Wagner, 1840." ''Annual Tropical Medicine and Parasitol'', 30, 8 April 1936:137-56. * 1936, Pawan, J. L. "Rabies in the vampire bat of Trinidad with Special Reference to the Clinical Course and the Latency of Infection." Reprinted from the ''Annals of Tropical Medicine and Parasitology''. Vol. 30, No. 4, December 1936. Issued by the Liverpool School of Tropical Medicine. * 1948, Pawan, J. L. "Fruit-Eating Bats and Paralytic Rabies in Trinidad." Reprinted from the ''Annals of Tropical Medicine and Parasitology'', Vol. 42, No. 2, September 1948, pp. 3–12. Issued by the Liverpool School of Tropical Medicine.


Awards

* In the King's Birthday Honours 1934 Pawan was appointed as a member of the
Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two o ...
for his ground-breaking discovery. * The
Pan American Health Organization The Pan American Health Organization (PAHO) is a specialized agency of the United Nations (UN) in charge of international health cooperation in the Americas. It fosters technical cooperation among member countries to fight communicable and non ...
(PAHO) posthumously named him a "Hero in Health" in 2002.


Footnotes


References

* Greehnall, Arthur M. (1963). Eulogy to Dr. John Lennox Pawan. Extrait de Rabies – Kuduz – La Rage – Tolwut. Vol. III. No. 1 Ocak-Janvier 1963, pp. 15–18. * Pawan, J. L. (1948). "Fruit-Eating Bat and Paralytic Rabies in Trinidad." Reprinted from the ''Annals of Tropical Medicine and Parasitology'', Vol. 42, No. 2; September 1948. Issued by the Liverpool School of Tropical Medicine.


External links


"Caribbean Icons in Science & Innovation. Joseph Lennox Pawan – Bacteriologist".
(A short biography.) Accessed 22 March 2011

(A short biography.) Accessed 22 March 2011

{{DEFAULTSORT:Pawan, Joseph Lennox Virologists 1887 births 1957 deaths Alumni of the University of Edinburgh Bacteriologists Trinidad and Tobago expatriates in France People educated at Saint Mary's College, Trinidad and Tobago Trinidad and Tobago biologists