Joseph M. DeSimone (born May 16, 1964) is an American
chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe ...
, inventor, and entrepreneur who has co-founded companies based on his research, including the American
3D printing
3D printing or additive manufacturing is the construction of a three-dimensional object from a CAD model or a digital 3D model. It can be done in a variety of processes in which material is deposited, joined or solidified under computer ...
technology company,
Carbon
Carbon () is a chemical element with the symbol C and atomic number 6. It is nonmetallic and tetravalent—its atom making four electrons available to form covalent chemical bonds. It belongs to group 14 of the periodic table. Carbon makes ...
, of which he was
CEO
A chief executive officer (CEO), also known as a central executive officer (CEO), chief administrator officer (CAO) or just chief executive (CE), is one of a number of corporate executives charged with the management of an organization especiall ...
from 2014 until November 2019.
Currently, DeSimone is the Sanjiv Sam Gambhir Professor of Translational Medicine in the Department of Radiology at
Stanford University, where he is also Professor of Chemical Engineering. He joined the faculty at Stanford in 2020. In 2020, he was also elected to the board of trustees of the
National Geographic Society
The National Geographic Society (NGS), headquartered in Washington, D.C., United States, is one of the largest non-profit scientific and educational organizations in the world.
Founded in 1888, its interests include geography, archaeology, ...
. DeSimone previously held a joint appointment as the Chancellor's Eminent Professor of Chemistry at the
University of North Carolina at Chapel Hill
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase ''universitas magistrorum et scholarium'', which r ...
and
William R. Kenan Jr.
William Rand Kenan Jr. (April 30, 1872 – July 28, 1965) was an American chemist, engineer, manufacturer, dairy farmer, and philanthropist.
Early life
William Rand Kenan Jr. was born in Wilmington, North Carolina, on April 30, 1872., son of Willi ...
Distinguished Professor of Chemical Engineering at
North Carolina State University
North Carolina State University (NC State) is a public land-grant research university in Raleigh, North Carolina. Founded in 1887 and part of the University of North Carolina system, it is the largest university in the Carolinas. The universi ...
.
DeSimone has published over 350 scientific articles and has over 200 issued patents in his name with over 200 patents pending. He was awarded the 2020
Harvey Prize
Harvey Prize is an annual Israeli award for breakthroughs in science and technology, as well as contributions to peace in the Middle East granted by the Technion in Haifa.
History
The prize is named for industrialist and inventor Leo Harvey. T ...
for "significant contributions to materials science, chemistry, polymer science nano medicine, and 3D printing".
Education
DeSimone received his BS in Chemistry in 1986 from
Ursinus College
Ursinus College is a private liberal arts college in Collegeville, Pennsylvania. It was founded in 1869 and occupies a 170-acre campus.
History
19th century
In 1867, members of the German Reformed Church began plans to establish a college wh ...
in
Collegeville, Pennsylvania
Collegeville is a borough in Montgomery County, Pennsylvania, a suburb outside of Philadelphia on Perkiomen Creek. Collegeville was incorporated in 1896. It is the location of Ursinus College which opened in 1869. The population was 5,089 at t ...
and his PhD in Chemistry in 1990 from
Virginia Tech
Virginia Tech (formally the Virginia Polytechnic Institute and State University and informally VT, or VPI) is a Public university, public Land-grant college, land-grant research university with its main campus in Blacksburg, Virginia. It also ...
in
Blacksburg, Virginia
Blacksburg is an incorporated town in Montgomery County, Virginia, United States, with a population of 44,826 at the 2020 census. Blacksburg, as well as the surrounding county, is dominated economically and demographically by the presence of ...
.
Career
DeSimone is a member of the
National Academy of Medicine
The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, En ...
(2014),
National Academy of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
(2012), and the
National Academy of Engineering
The National Academy of Engineering (NAE) is an American nonprofit, non-governmental organization. The National Academy of Engineering is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of ...
(2005). He is also a member of the
American Academy of Arts and Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, ...
(2005).
In the 1990s, at the
University of North Carolina at Chapel Hill
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase ''universitas magistrorum et scholarium'', which r ...
, he developed an environmentally friendly manufacturing process that relies on
supercritical carbon dioxide
Supercritical carbon dioxide (s) is a fluid state of carbon dioxide where it is held at or above its critical temperature and critical pressure.
Carbon dioxide usually behaves as a gas in air at standard temperature and pressure (STP), or a ...
instead of water and bio-persistent
surfactant
Surfactants are chemical compounds that decrease the surface tension between two liquids, between a gas and a liquid, or interfacial tension between a liquid and a solid. Surfactants may act as detergents, wetting agents, emulsifiers, fo ...
s for the creation of
fluoropolymer
A fluoropolymer is a fluorocarbon-based polymer with multiple carbon–fluorine bonds. It is characterized by a high resistance to solvents, acids, and bases. The best known fluoropolymer is polytetrafluoroethylene under the brand name "Teflon, ...
s or
high-performance plastics, such as
Teflon
Polytetrafluoroethylene (PTFE) is a synthetic fluoropolymer of tetrafluoroethylene that has numerous applications. It is one of the best-known and widely applied PFAS. The commonly known brand name of PTFE-based composition is Teflon by Chem ...
.
In 2002 DeSimone, along with Richard Stack, a cardiologist at
Duke University, co-founded Bioabsorbable Vascular Solutions (BVS) to commercialize a fully bioabsorbable, drug-eluting
stent
In medicine, a stent is a metal or plastic tube inserted into the lumen of an anatomic vessel or duct to keep the passageway open, and stenting is the placement of a stent. A wide variety of stents are used for different purposes, from expandab ...
for the treatment of
coronary artery disease
Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves Ischemia, the reduction of blood flow to the myocardium, heart muscle due to build-up o ...
. BVS was acquired by
Guidant in 2003.
As a professor at the
University of North Carolina at Chapel Hill
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase ''universitas magistrorum et scholarium'', which r ...
and
North Carolina State University
North Carolina State University (NC State) is a public land-grant research university in Raleigh, North Carolina. Founded in 1887 and part of the University of North Carolina system, it is the largest university in the Carolinas. The universi ...
, DeSimone and members of his academic laboratory also developed the nanoparticle fabrication technology, PRINT (Particle Replication in Non-Wetting Templates), leading DeSimone and students to co-found the company
Liquidia Technologiesin 2004. Liquidia develops PRINT particle-based medical treatments and became a publicly traded company in 2018. At the University of North Carolina at Chapel Hill, the PRINT technology also became a foundation for the
Carolina Center for Cancer Nanotechnology Excellence funded by the
National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. T ...
.
In 2015, DeSimone and colleagues published a paper in ''
Science Magazine
''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals.
It was first published in 1880, ...
'' on their invention of a rapid polymer 3D printing technology,
Continuous Liquid Interface Production (CLIP). The company,
Carbon
Carbon () is a chemical element with the symbol C and atomic number 6. It is nonmetallic and tetravalent—its atom making four electrons available to form covalent chemical bonds. It belongs to group 14 of the periodic table. Carbon makes ...
, which DeSimone co-founded, now develops printers with the CLIP technology. The printers are used to make end-use parts and products in several industries, including by the companies
Adidas, Resolution Medical, and
Ford. Recently, DeSimone has also been involved in the digital fabrication space using computational design to speed up the former method.
Awards and honors
DeSimone is the recipient of the 2000 Oliver Max Gardner Award from the University of North Carolina; the 2002 Engineering Excellence Award by DuPont; the 2002 Wallace H. Carothers Award from the Delaware Section of the
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all ...
; the 2002
John Scott Award presented by the Board of Directors of City Trusts, Philadelphia, given to "the most deserving" men and women whose inventions have contributed in some outstanding way to the "comfort, welfare and happiness" of mankind; the 2005 American Chemical Society Award for Creative Invention; the 2007 Collaboration Success Award from the
Council for Chemical Research
Council for Chemical Research is an organization based in Washington, DC, whose membership represents the U.S. chemical research enterprise. CCR was formed in 1979 to promote cooperation in basic research and encourage high-quality education in th ...
; the 2008
Lemelson–MIT Prize, the 2009
North Carolina Award The North Carolina Award is the highest civilian award bestowed by the U.S. state of North Carolina. It is awarded in the four fields of science, literature, the fine arts, and public service. Sometimes referred to as the "Nobel Prize of North Carol ...
; the 2009
NIH Director's Pioneer Award; the 2010
AAAS
AAAS may refer to:
* American Academy of Arts and Sciences, a learned society and center for policy research; the publisher of the journal ''Dædalus''
* American Association for the Advancement of Science, an organization that supports scientifi ...
Mentor Award in recognition of his efforts to advance diversity in the chemistry PhD workforce; the 2012 Walston Chubb Award for Innovation; the 2014 American Chemical Societ