Joseph DeSimone
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Joseph M. DeSimone (born May 16, 1964) is an American
chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a graduated scientist trained in the study of chemistry, or an officially enrolled student in the field. Chemists study the composition of ...
, inventor, and entrepreneur who has co-founded companies based on his research, including the American
3D printing 3D printing, or additive manufacturing, is the construction of a three-dimensional object from a CAD model or a digital 3D model. It can be done in a variety of processes in which material is deposited, joined or solidified under computer ...
technology company,
Carbon Carbon () is a chemical element; it has chemical symbol, symbol C and atomic number 6. It is nonmetallic and tetravalence, tetravalent—meaning that its atoms are able to form up to four covalent bonds due to its valence shell exhibiting 4 ...
, of which he was
CEO A chief executive officer (CEO), also known as a chief executive or managing director, is the top-ranking corporate officer charged with the management of an organization, usually a company or a nonprofit organization. CEOs find roles in variou ...
from 2014 until November 2019. Currently, DeSimone is the Sanjiv Sam Gambhir Professor of Translational Medicine in the department of radiology at
Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...
, where he is also professor of chemical engineering. He joined the faculty at Stanford in 2020. In 2020, he was also elected to the board of trustees of the
National Geographic Society The National Geographic Society, headquartered in Washington, D.C., United States, is one of the largest nonprofit scientific and educational organizations in the world. Founded in 1888, its interests include geography, archaeology, natural sc ...
. DeSimone previously held a joint appointment as the Chancellor's Eminent Professor of Chemistry at the
University of North Carolina at Chapel Hill The University of North Carolina at Chapel Hill (UNC, UNC–Chapel Hill, or simply Carolina) is a public university, public research university in Chapel Hill, North Carolina, United States. Chartered in 1789, the university first began enrolli ...
and William R. Kenan Jr. Distinguished Professor of Chemical Engineering at
North Carolina State University North Carolina State University (NC State, North Carolina State, NC State University, or NCSU) is a public university, public Land-grant university, land-grant research university in Raleigh, North Carolina, United States. Founded in 1887 and p ...
.


Education

DeSimone received his BS in chemistry in 1986 from
Ursinus College Ursinus College is a private liberal arts college in Collegeville, Pennsylvania. It was founded in 1869 and occupies a campus. Ursinus College's forerunner was the Freeland Seminary founded in 1848. Its $127 million endowment supports about 1, ...
in
Collegeville, Pennsylvania Collegeville is a borough in Montgomery County, Pennsylvania, a suburb outside of Philadelphia on Perkiomen Creek. Collegeville was incorporated in 1896. It is the location of Ursinus College, which opened in 1869. The population was 5,089 ...
and his PhD in chemistry in 1990 from
Virginia Tech The Virginia Polytechnic Institute and State University, commonly referred to as Virginia Tech (VT), is a Public university, public Land-grant college, land-grant research university with its main campus in Blacksburg, Virginia, United States ...
in Blacksburg, Virginia.


Career

DeSimone is a member of the
National Academy of Medicine The National Academy of Medicine (NAM), known as the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Engineerin ...
(2014),
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
(2012), and the
National Academy of Engineering The National Academy of Engineering (NAE) is an American Nonprofit organization, nonprofit, NGO, non-governmental organization. It is part of the National Academies of Sciences, Engineering, and Medicine (NASEM), along with the National Academ ...
(2005). He is also a member of the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
(2005). In the 1990s, at the
University of North Carolina at Chapel Hill The University of North Carolina at Chapel Hill (UNC, UNC–Chapel Hill, or simply Carolina) is a public university, public research university in Chapel Hill, North Carolina, United States. Chartered in 1789, the university first began enrolli ...
, he developed an environmentally friendly manufacturing process that relies on
supercritical carbon dioxide Supercritical carbon dioxide (s) is a fluid state of carbon dioxide where it is held at or above its critical temperature and critical pressure. Carbon dioxide usually behaves as a gas in air at standard temperature and pressure (STP), or a ...
instead of water and bio-persistent
surfactant Surfactants are chemical compounds that decrease the surface tension or interfacial tension between two liquids, a liquid and a gas, or a liquid and a solid. The word ''surfactant'' is a Blend word, blend of "surface-active agent", coined in ...
s for the creation of
fluoropolymer A fluoropolymer is a fluorocarbon-based polymer with multiple carbon–fluorine bonds. It is characterized by a high resistance to solvents, acids, and bases. The best known fluoropolymer is polytetrafluoroethylene under the brand name "Teflon, ...
s or
high-performance plastics High-performance plastics are plastics that meet higher requirements than ''standard'' (Commodity plastics, commodity) or ''Engineering plastic, engineering'' plastics. They are more expensive and used in smaller amounts. Definition High perfo ...
, such as
Teflon Polytetrafluoroethylene (PTFE) is a synthetic fluoropolymer of tetrafluoroethylene, and has numerous applications because it is chemically inert. The commonly known brand name of PTFE-based composition is Teflon by Chemours, a spin-off from ...
. In 2002 DeSimone, along with Richard Stack, a cardiologist at
Duke University Duke University is a Private university, private research university in Durham, North Carolina, United States. Founded by Methodists and Quakers in the present-day city of Trinity, North Carolina, Trinity in 1838, the school moved to Durham in 1 ...
, co-founded Bioabsorbable Vascular Solutions (BVS) to commercialize a fully bioabsorbable, drug-eluting
stent In medicine, a stent is a tube usually constructed of a metallic alloy or a polymer. It is inserted into the Lumen (anatomy), lumen (hollow space) of an anatomic vessel or duct to keep the passageway open. Stenting refers to the placement of ...
for the treatment of
coronary artery disease Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), is a type of cardiovascular disease, heart disease involving Ischemia, the reduction of blood flow to the cardiac muscle due to a build-up ...
. As a professor at the
University of North Carolina at Chapel Hill The University of North Carolina at Chapel Hill (UNC, UNC–Chapel Hill, or simply Carolina) is a public university, public research university in Chapel Hill, North Carolina, United States. Chartered in 1789, the university first began enrolli ...
and
North Carolina State University North Carolina State University (NC State, North Carolina State, NC State University, or NCSU) is a public university, public Land-grant university, land-grant research university in Raleigh, North Carolina, United States. Founded in 1887 and p ...
, DeSimone and members of his academic laboratory also developed the nanoparticle fabrication technology, PRINT (Particle Replication in Non-Wetting Templates), leading DeSimone and students to co-found the company Liquidia Technologies in 2004. Liquidia develops PRINT particle-based medical treatments and became a publicly traded company in 2018. At the University of North Carolina at Chapel Hill, the PRINT technology also became a foundation for the Carolina Center for Cancer Nanotechnology Excellence funded by the
National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...
. In 2015, DeSimone and colleagues published a paper in ''
Science Magazine ''Science'' is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscrib ...
'' on their invention of a rapid polymer 3D printing technology, Continuous Liquid Interface Production (CLIP). The company,
Carbon Carbon () is a chemical element; it has chemical symbol, symbol C and atomic number 6. It is nonmetallic and tetravalence, tetravalent—meaning that its atoms are able to form up to four covalent bonds due to its valence shell exhibiting 4 ...
, which DeSimone co-founded, now develops printers with the CLIP technology. The printers are used to make end-use parts and products in several industries, including by the companies
Adidas Adidas AG (; stylized in all lowercase since 1949) is a German athletic apparel and footwear corporation headquartered in Herzogenaurach, Bavaria, Germany. It is the largest sportswear manufacturer in Europe, and the second largest in the ...
, Resolution Medical, and Ford. Recently, DeSimone has also been involved in the digital fabrication space using computational design to speed up the former method.


Awards and honors

DeSimone is the recipient of the 2002
John Scott Award John Scott Award, created in 1816 as the John Scott Legacy Medal and Premium, is presented to men and women whose inventions improved the "comfort, welfare, and happiness of human kind" in a significant way. "...the John Scott Medal Fund, establish ...
presented by the Board of Directors of City Trusts, Philadelphia, given to "the most deserving" men and women whose inventions have contributed in some outstanding way to the "comfort, welfare and happiness" of mankind; the 2008
Lemelson–MIT Prize The Lemelson–MIT Program awards several prizes yearly to inventors in the United States. The largest is the Lemelson–MIT Prize which was endowed in 1994 by Jerome H. Lemelson, funded by the Lemelson Foundation, and is administered through the ...
, the 2009 North Carolina Award; the 2009 NIH Director's Pioneer Award; the 2014 Dickson Prize in Science; and the 2014 IRI Medal. DeSimone was awarded the
National Medal of Technology and Innovation The National Medal of Technology and Innovation (formerly the National Medal of Technology) is an honor granted by the president of the United States to American inventors and innovators who have made significant contributions to the development ...
, the highest honor in the U.S. for achievements related to technological progress, by
President President most commonly refers to: *President (corporate title) * President (education), a leader of a college or university *President (government title) President may also refer to: Arts and entertainment Film and television *'' Præsident ...
Barack Obama Barack Hussein Obama II (born August 4, 1961) is an American politician who was the 44th president of the United States from 2009 to 2017. A member of the Democratic Party, he was the first African American president in American history. O ...
at the White House in May 2016. In 2017, Dr. DeSimone received the 22nd Annual
Heinz Award The Heinz Awards are individual achievement honors given annually by the Heinz Foundations, Heinz Family Foundation. The Heinz Awards each year recognize outstanding individuals for their innovative contributions in three areas: the Arts, the Eco ...
in Technology, the Economy, and Employment. In 2019, DeSimone received the
Wilhelm Exner Medal The Wilhelm Exner Medal has been awarded by the Austrian Industry Association, (ÖGV), for excellence in research and science since 1921. The medal is dedicated to Wilhelm Exner (1840–1931), former president of the Association, who initialize ...
in ''Polymer Manufacturing''. Also in 2019, he was named the U.S. Entrepreneur Of The Year, National Overall Award winner by
Ernst & Young EY, previously known as Ernst & Young, is a multinational corporation, multinational professional services partnership, network based in London, United Kingdom. Along with Deloitte, KPMG and PwC, it is one of the Big Four accounting firms, Big F ...
. For the years 2019-2020 he was awarded the
Harvey Prize The Harvey Prize is an annual Israeli award for breakthroughs in science and technology, as well as contributions to peace in the Middle East granted by the Technion – Israel Institute of Technology, Technion in Haifa. The prize has become a ...
of the Technion in Israel. In 2021, he received the
Charles Goodyear Medal The Charles Goodyear Medal is the highest honor conferred by the American Chemical Society#Organization, American Chemical Society, Rubber Division. Established in 1941, the award is named after Charles Goodyear, the discoverer of vulcanization, ...
from the
American Chemical Society The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all ...
Rubber Division.


References


External links


Oral history interview transcript with Joseph DeSimone on 24 May 2021, American Institute of Physics, Niels Bohr Library & Archives
{{DEFAULTSORT:Desimone, Joseph 1964 births Living people American chemical engineers American chemical industry businesspeople Fellows of the American Academy of Arts and Sciences Lemelson–MIT Prize Members of the United States National Academy of Engineering Members of the United States National Academy of Sciences Ursinus College alumni Fellows of the American Institute for Medical and Biological Engineering Virginia Tech alumni Members of the National Academy of Medicine