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Sir John Stewart Savill, FRS, FMedSci (born 25 April 1957) is the Chief Executive of the Medical Research Council (MRC) in the UK and the Head of the College of Medicine and Veterinary Medicine and a Vice Principal of the
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
.


Education

Savill was educated at
St Catherine's College, Oxford St Catherine's College (colloquially called St Catz or Catz) is one of the Colleges of the University of Oxford, constituent colleges of the University of Oxford. In 1974, it was also one of the first men's colleges to admit women. It has 528 un ...
and the
University of Sheffield The University of Sheffield (informally Sheffield University or TUOS) is a public university, public research university in Sheffield, South Yorkshire, England. Its history traces back to the foundation of Sheffield Medical School in 1828, Fir ...
where he gained his
Bachelor of Medicine, Bachelor of Surgery A Bachelor of Medicine, Bachelor of Surgery (; MBBS, also abbreviated as BM BS, MB ChB, MB BCh, or MB BChir) is a medical degree granted by medical schools or universities in countries that adhere to the United Kingdom's higher education trad ...
in 1981 Savill was awarded a PhD for his work on
macrophage Macrophages (; abbreviated MPhi, φ, MΦ or MP) are a type of white blood cell of the innate immune system that engulf and digest pathogens, such as cancer cells, microbes, cellular debris and foreign substances, which do not have proteins that ...
s from the
Royal Postgraduate Medical School The Royal Postgraduate Medical School (RPMS) was an independent medical school, based primarily at Hammersmith Hospital in west London. In 1988, the school merged with the Institute of Obstetrics & Gynaecology, and in 1997 became part of Imperial ...
in 1989.


Research and career

Savill is widely known for his research is on
apoptosis Apoptosis (from ) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. Biochemistry, Biochemical events lead to characteristic cell changes (Morphology (biol ...
and
immunology Immunology is a branch of biology and medicine that covers the study of Immune system, immune systems in all Organism, organisms. Immunology charts, measures, and contextualizes the Physiology, physiological functioning of the immune system in ...
. Savill is active in acute general medicine and is an Honorary Consultant Physician and Nephrologist with the Lothian University Hospitals Division. He is a member of the Lothian Health Board and chairs its Service Redesign Committee. Savill has extensive experience in peer review and has a particular interest in research and development, and the career structures necessary for this, having chaired the
Academy of Medical Sciences The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academy, National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its ...
Working Party on Clinical Academic Careers. John Savill's research interests revolve around the role of cell death and
macrophages Macrophages (; abbreviated MPhi, φ, MΦ or MP) are a type of white blood cell of the innate immune system that engulf and digest pathogens, such as cancer cells, microbes, cellular debris and foreign substances, which do not have proteins that ...
in resolution and repair of inflammation, especially inflammatory disorders of the kidney glomerulus (
glomerulonephritis Glomerulonephritis (GN) is a term used to refer to several kidney diseases (usually affecting both kidneys). Many of the diseases are characterised by inflammation either of the glomeruli or of the small blood vessels in the kidneys, hence the ...
) and interstitium (
tubulointerstitial nephritis Interstitial nephritis, also known as tubulointerstitial nephritis, is inflammation of the area of the kidney known as the renal interstitium, which consists of a collection of cells, extracellular matrix, and fluid surrounding the renal tubules. ...
).


Present roles

* Vice Principal and Head of the College of Medicine and Veterinary Medicine at the
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
since October 2002. * Professor of Experimental Medicine since 1998. * Chair of Medicine since 1998 * Chairman of the Physiological Systems and Clinical Sciences Board of the MRC, and is a full member of the Council itself. * Chief Executive of the Medical Research Council UK since 1 October 2010. As of 2015, Savill was paid a salary of between £170,000 and £174,999 by the MRC, making him one of the 328 most highly paid people in the British public sector at that time.


Previous roles

* Director of the Medical Research Council (MRC) and University of Edinburgh Centre for Inflammation Research, where he continues to direct a group interested in the molecular cell biology of renal inflammation. * Professor of Medicine since 1998, a role he vacated in 1998.


Awards and honours

He was appointed
Knight Bachelor The title of Knight Bachelor is the basic rank granted to a man who has been knighted by the monarch but not inducted as a member of one of the organised Order of chivalry, orders of chivalry; it is a part of the Orders, decorations, and medals ...
in the
2008 New Year Honours The New Year Honours 2008 for the Commonwealth realms were announced on 29 December 2007, to celebrate the year passed and mark the beginning of 2008. The recipients of honours are displayed here as they were styled before their new honour, and ...
. He was also elected a
Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, incl ...
(FRS) in 2013, awarded Fellowship of the Royal College of Physicians (FRCP), elected a
Fellow of the Academy of Medical Sciences Fellowship of the Academy of Medical Sciences (FMedSci) is an award for medical scientists who are judged by the UK Academy of Medical Sciences for the "excellence of their science, their contribution to medicine and society and the range of the ...
(FMedSci) and a
Fellow of the Royal Society of Edinburgh Fellowship of the Royal Society of Edinburgh (FRSE) is an award granted to individuals that the Royal Society of Edinburgh, Scotland's national academy of science and Literature, letters, judged to be "eminently distinguished in their subject". ...
(FRSE). He is an honorary member of the
British Society for Immunology The British Society for Immunology, or BSI, is a UK-based organisation of British immunologists but accepts members from all countries. It was founded in November 1956 by John H. Humphrey, Robin Coombs, Bob White, and Avrion Mitchison and is ...
. In 1999 he was elected a member of the
Harveian Society of Edinburgh The Harveian Society of Edinburgh was founded in April 1782 by Andrew Duncan (physician, born 1744), Andrew Duncan. The Society holds an annual Festival in honour of the life and works of William Harvey, the physician who first correctly des ...
and in 2009 he served as President of the Society. He was elected a Fellow of the
Australian Academy of Health and Medical Sciences The Australian Academy of Health and Medical Sciences is an academy to promote health and medical sciences in Australia. It was established in June 2014. It cites "The Academy will serve the three purposes identified as of high priority in the 2 ...
in 2021.


References

, - {{DEFAULTSORT:Savill, John Academics of the University of Edinburgh Knights Bachelor Fellows of the Royal Society Living people 1957 births Fellows of the Academy of Medical Sciences (United Kingdom) Fellows of the Australian Academy of Health and Medical Sciences Alumni of the University of Sheffield Alumni of the University of Oxford Office bearers of the Harveian Society of Edinburgh Members of the Harveian Society of Edinburgh