John Rodney Guest, FRS (born 27 December 1935) is a British molecular microbiologist. He was born the son of Sidney Ramsey Guest in Leeds, West Yorkshire and educated at the

University of Leeds The University of Leeds is a public research university in Leeds, West Yorkshire, England. It was established in 1874 as the Yorkshire College of Science. In 1884, it merged with the Leeds School of Medicine (established 1831) and was renamed Y ...

(B.Sc. 1957) and

Trinity College, Oxford Trinity College (full name: The College of the Holy and Undivided Trinity in the University of Oxford, of the foundation of Sir Thomas Pope (Knight)) is a Colleges of the University of Oxford, constituent college of the University of Oxford in E ...

(Ph.D. 1961). He worked as a Fellow at Oxford University from 1960 to 1965 and as a

Fulbright Scholar The Fulbright Program, including the Fulbright–Hays Program, is one of several United States cultural exchange programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the peopl ...

Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...

in 1963–64. He was appointed Lecturer in Microbiology at the

University of Sheffield The University of Sheffield (informally Sheffield University or TUOS) is a public university, public research university in Sheffield, South Yorkshire, England. Its history traces back to the foundation of Sheffield Medical School in 1828, Fir ...

from 1965 to 1968, Senior Lecturer and Reader from 1968 to 1981 and has been Professor of Microbiology at Sheffield since 1981. He is known for his work on the application of mutant and genetic approaches to define the biochemistry and genetic make-up of central

anabolic Anabolism () is the set of metabolic pathways that construct macromolecules like DNA or RNA from smaller units. These reactions require energy, known also as an endergonic process. Anabolism is the building-up aspect of metabolism, whereas catab ...

and

catabolic pathway Catabolism () is the set of metabolic pathways that breaks down molecules into smaller units that are either oxidized to release energy or used in other anabolic reactions. Catabolism breaks down large molecules (such as polysaccharides, lipid ...

s of bacteria, in particular the

citric acid cycle The citric acid cycle—also known as the Krebs cycle, Szent–Györgyi–Krebs cycle, or TCA cycle (tricarboxylic acid cycle)—is a series of chemical reaction, biochemical reactions that release the energy stored in nutrients through acetyl-Co ...

and related functions in both

aerobic Aerobic means "requiring air," in which "air" usually means oxygen. Aerobic may also refer to * Aerobic exercise, prolonged exercise of moderate intensity * Aerobics, a form of aerobic exercise * Aerobic respiration, the aerobic process of cellu ...

and

anaerobic metabolism Anaerobic respiration is respiration using electron acceptors other than molecular oxygen (O2). Although oxygen is not the final electron acceptor, the process still uses a respiratory electron transport chain. In aerobic organisms undergoing ...

. In 1986 he was elected a

Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, incl ...

and delivered their

Leeuwenhoek Lecture The Leeuwenhoek Lecture is a prize lecture of the Royal Society to recognize achievement in microbiology. The prize was originally given in 1950 and awarded annually, but from 2006 to 2018 was given triennially. From 2018 it will be awarded bienni ...

in 1995 on the subject of life without oxygen. He married Barbara Dearsley in 1962 and had a son (Chris Guest b.1968) and 2 daughters (Sue Guest b.1963 and Julia Guest b.1965).

References

{{DEFAULTSORT:Guest, John Rodney 1935 births Living people British microbiologists Alumni of the University of Leeds Alumni of Trinity College, Oxford Fellows of the Royal Society Academics of the University of Sheffield