John Danesh is a Professor of

Epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent dise ...

and Medicine and the head of the Department of Public Health and Primary Care at the

University of Cambridge The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, wo ...

. He also holds several other leadership roles in scientific organizations, including director of the department's affiliate

Strangeways Research Laboratory Strangeways Research Laboratory is a research institution in Cambridge, United Kingdom. It was founded by Thomas Strangeways in 1905 as the Cambridge Research Hospital and acquired its current name in 1928. Organised as an independent charity, ...

and founder and director of the Cardiovascular Epidemiology Unit. He is also an associate faculty member at the

Wellcome Trust Sanger Institute The Wellcome Sanger Institute, previously known as The Sanger Centre and Wellcome Trust Sanger Institute, is a non-profit organisation, non-profit British genomics and genetics research institute, primarily funded by the Wellcome Trust. It is l ...

and an honorary consultant at the

Cambridge University Hospitals NHS Foundation Trust Cambridge University Hospitals NHS Foundation Trust is an NHS foundation trust located in Cambridge, England. The Trust provides healthcare for people in the Cambridge area, in eastern England, and specialist services such as Organ transplantati ...

. He became a fellow of the

Royal College of Physicians The Royal College of Physicians of London, commonly referred to simply as the Royal College of Physicians (RCP), is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of ph ...

in 2007 and of the

Academy of Medical Sciences The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academy, National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its ...

in 2015. Professor Danesh has been the

British Heart Foundation The British Heart Foundation (BHF) is a cardiovascular research charity in the United Kingdom. It funds medical research related to heart and circulatory diseases and their risk factors, and runs influencing work aimed at shaping public policy ...

Professor of Medicine and Epidemiology since 2012. In 2013 he won the Senior Investigator award from the

National Institute for Health and Care Research The National Institute for Health and Care Research (NIHR) is the British government's major funder of clinical, public health, social care and translational research. With a budget of over £1.2 billion in 2020–21, its mission is to "impr ...

(NIHR).

Education

Danesh was educated in New Zealand and Australia, studying medicine at the

University of Otago The University of Otago () is a public university, public research university, research collegiate university based in Dunedin, Otago, New Zealand. Founded in 1869, Otago is New Zealand's oldest university and one of the oldest universities in ...

in and the

Royal Melbourne Hospital The Royal Melbourne Hospital (RMH), located in Parkville, Victoria, an inner suburb of Melbourne, is one of Australia's leading public hospitals. It is a major teaching hospital for tertiary health care with a reputation in clinical research. Th ...

. He was a

Rhodes scholar The Rhodes Scholarship is an international Postgraduate education, postgraduate award for students to study at the University of Oxford in Oxford, United Kingdom. The scholarship is open to people from all backgrounds around the world. Esta ...

(awarded 1992) who earned an MSc from the

London School of Hygiene and Tropical Medicine The London School of Hygiene & Tropical Medicine (LSHTM) is a public university, public research university in Bloomsbury, central London, and a constituent college, member institution of the University of London that specialises in public hea ...

and a

DPhil A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of graduate study and original research. The name of the deg ...

from the

University of Oxford The University of Oxford is a collegiate university, collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the List of oldest un ...

, both in

epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent dise ...

Research

Danesh's interest is in the

genetic epidemiology Genetic epidemiology is the study of the role of genetic factors in determining health and disease in families and in populations, and the interplay of such genetic factors with environmental factors. Genetic epidemiology seeks to derive a statist ...

cardiovascular disease Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumati ...

. He has conducted large-scale genetic studies of heart disease risk across multinational populations and his work has often been cited in guidelines for clinical practice. Among his most widely cited research results is the observation that

C-reactive protein C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin ...

is only moderately predictive of

coronary heart disease Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), is a type of cardiovascular disease, heart disease involving Ischemia, the reduction of blood flow to the cardiac muscle due to a build-up ...

References

{{DEFAULTSORT:Danesh, John 21st-century British medical doctors British public health doctors Living people Professors of the University of Cambridge Year of birth missing (living people) NIHR Senior Investigators Fellows of Jesus College, Cambridge Fellows of the Royal College of Physicians Fellows of the Academy of Medical Sciences (United Kingdom)