John Caffey
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John Patrick Caffey (March 30, 1895 – September 2, 1978) was an American
pediatrician Pediatrics (American English) also spelled paediatrics (British English), is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, pediatrics covers many of their youth ...
and
radiologist Radiology ( ) is the medical specialty that uses medical imaging to diagnose diseases and guide treatment within the bodies of humans and other animals. It began with radiography (which is why its name has a root referring to radiation), but tod ...
who is often referred to as one of the founders of pediatric radiology. He was the first to describe shaken baby syndrome,
infantile cortical hyperostosis Infantile cortical hyperostosis (ICH) is a self-limited inflammatory disorder of infants that causes bone changes, soft tissue swelling and irritability. The disease may be present at birth or occur shortly thereafter. The cause is unknown. Bo ...
, and Kenny-Caffey syndrome.


Early life

Caffey was born on March 30, 1895, in
Castle Gate, Utah Castle Gate is a ghost town in the Western United States, western United States, located in Carbon County, Utah, Carbon County in eastern Utah. A mining town approximately southeast of Salt Lake City, its name was derived from a rock forma ...
. He attended school in
Salt Lake City Salt Lake City, often shortened to Salt Lake or SLC, is the capital and most populous city of the U.S. state of Utah. It is the county seat of Salt Lake County, the most populous county in the state. The city is the core of the Salt Lake Ci ...
, Utah, before enrolling at the
University of Michigan The University of Michigan (U-M, U of M, or Michigan) is a public university, public research university in Ann Arbor, Michigan, United States. Founded in 1817, it is the oldest institution of higher education in the state. The University of Mi ...
, where he completed a Bachelor of Arts in 1916 and a Doctor of Medicine in 1919.


Career

Caffey interned at Barnes Hospital in St. Louis before traveling to postwar Europe in 1920, working with the
American Red Cross The American National Red Cross is a Nonprofit organization, nonprofit Humanitarianism, humanitarian organization that provides emergency assistance, disaster relief, and disaster preparedness education in the United States. Clara Barton founded ...
and
American Relief Administration American Relief Administration (ARA) was an American Humanitarian aid, relief mission to Europe and later Russian Civil War, post-revolutionary Russia after World War I. Herbert Hoover, future president of the United States, was the program dire ...
in Serbia, Poland and Russia. He returned to the United States in 1923, completing a residency in medicine at the University of Michigan and then an internship in
pediatrics Pediatrics (American English) also spelled paediatrics (British English), is the branch of medicine that involves the medical care of infants, children, Adolescence, adolescents, and young adults. In the United Kingdom, pediatrics covers many o ...
at Babies Hospital in New York City. He opened a private practice in 1925 while maintaining admitting rights at Babies Hospital. He was given the position of head of
radiology Radiology ( ) is the medical specialty that uses medical imaging to diagnose diseases and guide treatment within the bodies of humans and other animals. It began with radiography (which is why its name has a root referring to radiation), but tod ...
at Babies Hospital in 1929 after the chief of pediatrics overheard him complaining about the poor quality of a radiology conference at the hospital. When the chief of pediatrics asked if he could do any better, Caffey replied, "I could try." Pediatric radiology would go on to become his life's work, and he would receive radiographs mailed from across North America for his expert opinion. He was an avid researcher, publishing initially on the effects on the skeletal system of
lead poisoning Lead poisoning, also known as plumbism and saturnism, is a type of metal poisoning caused by lead in the body. Symptoms may include abdominal pain, constipation, headaches, irritability, memory problems, infertility, numbness and paresthesia, t ...
,
rickets Rickets, scientific nomenclature: rachitis (from Greek , meaning 'in or of the spine'), is a condition that results in weak or soft bones in children and may have either dietary deficiency or genetic causes. Symptoms include bowed legs, stun ...
,
bismuth Bismuth is a chemical element; it has symbol Bi and atomic number 83. It is a post-transition metal and one of the pnictogens, with chemical properties resembling its lighter group 15 siblings arsenic and antimony. Elemental bismuth occurs nat ...
,
hemophilia Haemophilia (British English), or hemophilia (American English) (), is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding for a long ...
,
vitamin A Vitamin A is a fat-soluble vitamin that is an essential nutrient. The term "vitamin A" encompasses a group of chemically related organic compounds that includes retinol, retinyl esters, and several provitamin (precursor) carotenoids, most not ...
poisoning,
syphilis Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms depend on the stage it presents: primary, secondary, latent syphilis, latent or tertiary. The prim ...
, and
hemolytic anemia Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular). This most commonl ...
s. He published ''Pediatric X-Ray Diagnosis'', the first definitive textbook on the topic, in 1945. Caffey was the first to describe what is now known as shaken baby syndrome with a 1946 article on the association between
long bone The long bones are those that are longer than they are wide. They are one of five types of bones: long, short, flat, irregular and sesamoid. Long bones, especially the femur and tibia, are subjected to most of the load during daily activities ...
fractures and
subdural hematoma A subdural hematoma (SDH) is a type of bleeding in which a collection of blood—usually but not always associated with a traumatic brain injury—gathers between the inner layer of the dura mater and the arachnoid mater of the meninges surrou ...
s in infants. He also provided the first description of
infantile cortical hyperostosis Infantile cortical hyperostosis (ICH) is a self-limited inflammatory disorder of infants that causes bone changes, soft tissue swelling and irritability. The disease may be present at birth or occur shortly thereafter. The cause is unknown. Bo ...
, also known as Caffey's disease. At Babies Hospital, Caffey was appointed professor of clinical pediatrics in 1950 and then professor of radiology in 1954. He retired from Babies Hospital in 1960 and joined the
Children's Hospital of Pittsburgh UPMC Children's Hospital of Pittsburgh (CHP), popularly known simply as Children's, is part of the University of Pittsburgh Medical Center and the only hospital in Greater Pittsburgh dedicated solely to the care of infants, children, teens an ...
in 1963 as a radiologist and a professor at
University of Pittsburgh School of Medicine The University of Pittsburgh School of Medicine is a medical school of the University of Pittsburgh, located in Pittsburgh, Pennsylvania. The School of Medicine, also known as Pitt Med, encompasses both a medical program, offering the doctor of ...
. He continued his research in Pittsburgh, describing the earliest radiological changes of Perthes disease and a new form of dwarfism, termed Kenny-Caffey syndrome. Caffey was a founding member of the
Society for Pediatric Radiology The Society for Pediatric Radiology is a professional association of Pediatric radiology, pediatric radiologists. The Society publishes the journal ''Pediatric Radiology (journal), Pediatric Radiology'' and holds a yearly meeting. It was founded i ...
, but was only eligible for the title of honorary counselor as he did not have formal qualifications in radiology. He received the
American Medical Association The American Medical Association (AMA) is an American professional association and lobbying group of physicians and medical students. This medical association was founded in 1847 and is headquartered in Chicago, Illinois. Membership was 271,660 ...
's Jacobi Award; the
American Pediatric Society The American Pediatric Society (APS) is the first pediatric society established in North America. Created in 1887, the APS pursues a vision of an engaged, inclusive, and impactful community of pediatric thought leaders. The APS mission is to shape t ...
's highest honor, the John Howland Award; and the
American College of Radiology The American College of Radiology (ACR), founded in 1923, is a professional medical society representing nearly 40,000 diagnostic radiologists, radiation oncologists, interventional radiologists, nuclear medicine physicians and medical physicists ...
's Gold Medal.


Death and legacy

Caffey died on September 2, 1978, at Presbyterian-University Hospital in Pittsburgh. He had continued working up until the morning of his hospital admission. The seventh edition of his textbook was published shortly before his death and, now known as ''Caffey's Pediatric Diagnostic Imaging'', is in its thirteenth edition as of 2021.


References

{{DEFAULTSORT:Caffey, John 1895 births 1978 deaths People from Carbon County, Utah American pediatricians American radiologists University of Michigan Medical School alumni University of Pittsburgh faculty 20th-century American physicians Physicians from Utah Recipients of the John Howland Award