Jo-Anna Downey (February 1, 1967—December 2016) was a Canadian

stand-up comedian Stand-up comedy is a performance directed to a live audience, where the performer stands on a stage and delivers humorous and satirical monologues sometimes incorporating physical acts. These performances are typically composed of rehear ...

. She was the host of two weekly

Toronto, Ontario Toronto ( , locally pronounced or ) is the List of the largest municipalities in Canada by population, most populous city in Canada. It is the capital city of the Provinces and territories of Canada, Canadian province of Ontario. With a p ...

comedy shows, ''Open Mike at Spirits'' (since 1996) and ''Standing on the Danforth''. Downey was diagnosed with

amyotrophic lateral sclerosis Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or—in the United States—Lou Gehrig's disease (LGD), is a rare, Terminal illness, terminal neurodegenerative disease, neurodegenerative disorder that results i ...

in 2012, and retired from performing in 2013. She died on December 1, 2016.

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* 1967 births 2016 deaths Canadian stand-up comedians Canadian women comedians Neurological disease deaths in Ontario Deaths from motor neuron disease in Canada 20th-century Canadian comedians 21st-century Canadian comedians 20th-century Canadian women Canadian Comedy Award winners Comedians from Montreal {{Canada-comedian-stub