Jane Hurst
   HOME

TheInfoList



OR:

Jane Louise Hurst is the William Prescott Professor of Animal Science at the
University of Liverpool The University of Liverpool (abbreviated UOL) is a Public university, public research university in Liverpool, England. Founded in 1881 as University College Liverpool, Victoria University (United Kingdom), Victoria University, it received Ro ...
. She is Head of Mammalian Behaviour & Evolution. She studies scent communication between mammals, as well as
animal welfare Animal welfare is the quality of life and overall well-being of animals. Formal standards of animal welfare vary between contexts, but are debated mostly by animal welfare groups, legislators, and academics. Animal welfare science uses measures ...
and pest control. She served as the president of the
Association for the Study of Animal Behaviour The Association for the Study of Animal Behaviour (ASAB) is a British organization founded in 1936 to promote ethology and the study of animal behaviour. ASAB holds conferences, offers grants, and publishes a peer-reviewed journal, ''Animal Behaviou ...
from 2010 to 2012.


Early life and education

Hurst earned her bachelor's degree in science at the
University of Birmingham The University of Birmingham (informally Birmingham University) is a Public university, public research university in Birmingham, England. It received its royal charter in 1900 as a successor to Queen's College, Birmingham (founded in 1825 as ...
. She was inspired to study
behavioural ecology Behavioral ecology, also spelled behavioural ecology, is the study of the evolutionary basis for animal behavior due to ecological pressures. Behavioral ecology emerged from ethology after Niko Tinbergen outlined four questions to address when ...
after reading ''Mice All Over'' by Peter Crowcroft. She earned her
PhD A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of graduate study and original research. The name of the deg ...
in 1984 on the
behavioural ecology Behavioral ecology, also spelled behavioural ecology, is the study of the evolutionary basis for animal behavior due to ecological pressures. Behavioral ecology emerged from ethology after Niko Tinbergen outlined four questions to address when ...
of the house mouse '' Mus domesticus''. Hurst became inspired after discovering Peter Crowcroft's book "Mice All Over". During her PhD she watched wild mice in agricultural buildings, studying their social organisation and ability to live at such high
population densities Population density (in agriculture: standing stock or plant density) is a measurement of population per unit land area. It is mostly applied to humans, but sometimes to other living organisms too. It is a key geographical term.Matt RosenberPopul ...
.


Research and career

Hurst joined the
University of Nottingham The University of Nottingham is a public research university in Nottingham, England. It was founded as University College Nottingham in 1881, and was granted a royal charter in 1948. Nottingham's main campus (University Park Campus, Nottingh ...
as a
postdoctoral researcher A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary acade ...
in 1985, obtained a
Science and Engineering Research Council The Science and Engineering Research Council (SERC) and its predecessor the Science Research Council (SRC) were the UK agencies in charge of publicly funded scientific and engineering research activities, including astronomy, biotechnology and bi ...
(SERC) Postdoctoral Research Fellowship from 1986 to 1988, a SERC Advanced Fellowship from 1989 to 1984 and an
Agricultural and Food Research Council The Agricultural and Food Research Council (AFRC) was a British Research Council responsible for funding and managing scientific and technological developments in farming and horticulture. History The AFRC was formed in 1983 from its predecessor ...
(AFRC)/
BBSRC Biotechnology and Biological Sciences Research Council (BBSRC), part of UK Research and Innovation, is a non-departmental public body (NDPB), and is the largest UK public funder of non-medical bioscience. It predominantly funds scientific res ...
Advanced Fellowship from 1994 to 1998. Hurst works on the mechanisms and evolution of
scent communication Animal communication is the transfer of information from one or a group of animals (sender or senders) to one or more other animals (receiver or receivers) that affects the current or future behavior of the receivers. Information may be sent int ...
in animals. She is interested in the roles of volatile and non-volatile scents. She was appointed the William Prescott Professor of Animal Science at the
University of Liverpool The University of Liverpool (abbreviated UOL) is a Public university, public research university in Liverpool, England. Founded in 1881 as University College Liverpool, Victoria University (United Kingdom), Victoria University, it received Ro ...
in 1998 and Head of Mammalian Behaviour & Evolution Group. Her main research interests are in the chemobiology of competitive signalling in mammals. Hurst became interested in the signals that determine animal
mate choice Mate choice is one of the primary mechanisms under which evolution can occur. It is characterized by a "selective response by animals to particular stimuli" which can be observed as behavior.Bateson, Paul Patrick Gordon. "Mate Choice." Mate Choi ...
. She is interested in how scents are used in sexual communications. She demonstrated that the quality of an animal's
odour An odor (American English) or odour (English in the Commonwealth of Nations, Commonwealth English; American and British English spelling differences#-our, -or, see spelling differences) is a smell or a scent caused by one or more volatilized ...
determines the chances that it will be selected as a mate. She found that female mice prefer to nest with their sisters, irrespective of whether they knew each other before. Specifically, female house mice prefer partners that share their own major urinary protein genotype. In the absence of this phenotype match, females preferred partners with whom they share multiple-loci across the
genome A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as ...
. Hurst identified a non-volatile
pheromone A pheromone () is a secreted or excreted chemical factor that triggers a social response in members of the same species. Pheromones are chemicals capable of acting like hormones outside the body of the secreting individual, to affect the behavio ...
that was released in male urine that female mice find highly attractive. She went on to find that this
pheromone A pheromone () is a secreted or excreted chemical factor that triggers a social response in members of the same species. Pheromones are chemicals capable of acting like hormones outside the body of the secreting individual, to affect the behavio ...
was a major urinary protein (MUP20), which she named darcin after
Mr Darcy Fitzwilliam Darcy Esquire, generally referred to as Mr. Darcy, is one of the two central characters in Jane Austen's 1813 novel ''Pride and Prejudice''. He is an archetype of the aloof romantic hero, and a romantic interest of Elizabeth Bennet, ...
in
Jane Austen Jane Austen ( ; 16 December 1775 – 18 July 1817) was an English novelist known primarily for #List of works, her six novels, which implicitly interpret, critique, and comment on the English landed gentry at the end of the 18th century ...
's novel ''
Pride and Prejudice ''Pride and Prejudice'' is the second published novel (but third to be written) by English author Jane Austen, written when she was age 20-21, and later published in 1813. A novel of manners, it follows the character development of Elizabe ...
''. Hurst went on to establish that this pheromone could stimulate both short and long-term learning and that darcin and other major urinary proteins influence the odour signature that female mice learn. She also showed that darcin increased
neurogenesis Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). This occurs in all species of animals except the porifera (sponges) and placozoans. Types of NSCs include neuroepithelial cells ( ...
in the
olfactory bulb The olfactory bulb (Latin: ''bulbus olfactorius'') is a neural structure of the vertebrate forebrain involved in olfaction, the sense of smell. It sends olfactory information to be further processed in the amygdala, the orbitofrontal cortex (OF ...
and hippocampus. and has been involved with work that has identified a genetically determined circuit extending from the accessory
olfactory bulb The olfactory bulb (Latin: ''bulbus olfactorius'') is a neural structure of the vertebrate forebrain involved in olfaction, the sense of smell. It sends olfactory information to be further processed in the amygdala, the orbitofrontal cortex (OF ...
to the posterior medial
amygdala The amygdala (; : amygdalae or amygdalas; also '; Latin from Greek language, Greek, , ', 'almond', 'tonsil') is a paired nucleus (neuroanatomy), nuclear complex present in the Cerebral hemisphere, cerebral hemispheres of vertebrates. It is c ...
mediating all behavioural responses to darcin. Hurst found that female mice are more attracted to male mice with their own territory. She found that darcin and other
major urinary proteins Major urinary proteins (Mups), also known as α2u-globulins, are a protein subfamily, subfamily of proteins found in abundance in the urine and other secretions of many animals. Mups provide a small range of identifying information about the don ...
influence the odour signature that female mice learn. She edited volume 11 of Chemical Signals in Vertebrates that followed a conference of the same name in Chester, UK. For her work on scent communication, Hurst was awarded the Zoological Society of London Frink Medal in 2023. Her research is directed in part to the development of humane control of rodent pests. She also identified non-aversive handling methods that would reduce anxiety in mice, allowing them to be more reliable in laboratory tests. Hurst developed the use of mouse-friendly handling tunnels, reducing their anxiety and allowing them to explore more during animal testing. Hurst is also interested in how animals can detect scent-cues of ill-health and disease. ] For this work, she was awarded the NC3Rs prize in 2010. Hurst is also interested in how animals can detect scent-cues of ill-health and disease. In 2010 Hurst was appointed President for the
Association for the Study of Animal Behaviour The Association for the Study of Animal Behaviour (ASAB) is a British organization founded in 1936 to promote ethology and the study of animal behaviour. ASAB holds conferences, offers grants, and publishes a peer-reviewed journal, ''Animal Behaviou ...
(ASAB). She has supported the 
Biotechnology and Biological Sciences Research Council Biotechnology and Biological Sciences Research Council (BBSRC), part of UK Research and Innovation, is a non-departmental public body (NDPB), and is the largest UK public funder of non-medical bioscience. It predominantly funds science, scient ...
(BBSRC) from 2000 – 2019 by serving on grant funding and strategy advisory panels, Appointments Board, and chaired the BBSRC Animal Welfare Programme steering committee. She has supported the National Centre for the Replacement, Refinement and Reduction of Animals in Research since its inception, including a founding member of the NC3Rs Board and grant funding panel (2004-2010). She has served on the Council for the Universities Federation for Animal Welfare (UFAW, 1996-2002), on the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
Use of Animals in Research committee (2004-2009) and the Ethical committee for ASAB (1991-1999, chair from 1995). Hurst has been involved with several studies to improve connections between researchers in the animal welfare community. Hurst discussed her
pheromone A pheromone () is a secreted or excreted chemical factor that triggers a social response in members of the same species. Pheromones are chemicals capable of acting like hormones outside the body of the secreting individual, to affect the behavio ...
research on ''
In Our Time In Our Time may refer to: * ''In Our Time'' (1944 film), a film starring Ida Lupino and Paul Henreid * ''In Our Time'' (1982 film), a Taiwanese anthology film featuring director Edward Yang; considered the beginning of the "New Taiwan Cinema" * ''In ...
'' in 2019. In 2021 she was the guest on an episode of the
BBC Radio 4 BBC Radio 4 is a British national radio station owned and operated by the BBC. The station replaced the BBC Home Service on 30 September 1967 and broadcasts a wide variety of spoken-word programmes from the BBC's headquarters at Broadcasti ...
programme,
The Life Scientific ''The Life Scientific'' is a BBC Radio 4 science programme, presented by Jim Al-Khalili, in which each episode is dedicated to the biography and work of a living scientist. The programme consists of an interview between Al-Khalili and the featur ...
.


Awards and honours

Her awards and honours include: *2017 ASAB Medal from the
Association for the Study of Animal Behaviour The Association for the Study of Animal Behaviour (ASAB) is a British organization founded in 1936 to promote ethology and the study of animal behaviour. ASAB holds conferences, offers grants, and publishes a peer-reviewed journal, ''Animal Behaviou ...
*2010 National Centre for the Replacement, Refinement and Reduction of Animals in Research 3Rs Prize *2019 Swiss Laboratory Animal Science Association Prize for Refinement *202
Universities Federation for Animal Welfare (UFAW)
Medal for Outstanding Contributions to Animal Welfare Science *2023 Zoological Society of London (ZSL)
Frink Medal The Frink Medal for British Zoologists is awarded by the Zoological Society of London "for significant and original contributions by a professional zoologist to the development of zoology." It consists of a bronze plaque (76 by 83 millimetres), dep ...
'For significant and original contributions by a professional zoologist to the development of zoology' She was appointed
Officer of the Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two o ...
(OBE) in the
2020 New Year Honours The 2020 New Year Honours are appointments by some of the 16 Commonwealth realms to various orders and honours to recognise and reward good works by citizens of those countries. The New Year Honours are awarded as part of the New Year celebratio ...
for services to animal welfare.


References

{{DEFAULTSORT:Hurst, Jane Living people Year of birth missing (living people) Academics of the University of Liverpool Academics of the University of Nottingham Alumni of the University of Birmingham British animal welfare scholars British ecologists British women scientists Fellows of the Royal Society of Biology Officers of the Order of the British Empire Women ecologists Presidents of the Association for the Study of Animal Behaviour