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Dr. Jane Hinton (1919–2003) was a pioneer in the study of bacterial antibiotic resistance and one of the first two African-American women to gain the degree of
Doctor of Veterinary Medicine Doctor, Doctors, The Doctor or The Doctors may refer to: Titles and occupations * Physician, a medical practitioner * Doctor (title), an academic title for the holder of a doctoral-level degree ** Doctorate ** List of doctoral degrees awarded ...
(1949). Prior to her veterinary medicine studies at the
University of Pennsylvania The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of f ...
, she had been a laboratory technician at
Harvard Harvard University is a private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher lear ...
, co-developing the
Mueller–Hinton agar Mueller Hinton agar is a type of growth medium used in microbiology to culture bacterial isolates and test their susceptibility to antibiotics. This medium was first developed in 1941 by John Howard Mueller and Jane Hinton, who were microbiologis ...
, a culture medium that is now commonly used to test bacterial susceptibility to antibiotics. She later practiced as a small animal veterinarian in Massachusetts, and then as a federal government inspector investigating disease outbreak in livestock for the Department of Agriculture.


Early life and education

Jane Hinton was born on May 1, 1919. Her father, William Augustus Hinton (1883–1959), was a
bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology— a subdivision of microbiology that studies bacteria, typically Pathogenic bacteria, pathogenic ones. Bacteriologists are interested in studying and learnin ...
and
pathologist Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
who was an expert in the diagnosis and treatment of
syphilis Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms depend on the stage it presents: primary, secondary, latent syphilis, latent or tertiary. The prim ...
, including the development of tests for syphilis. The son of former slaves, he was the first African-American professor at
Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
and the first African-American author of a textbook. He entered laboratory medicine because
racism Racism is the belief that groups of humans possess different behavioral traits corresponding to inherited attributes and can be divided based on the superiority of one Race (human categorization), race or ethnicity over another. It may also me ...
in Boston prevented him from gaining an internship in medicine. Jane Hinton's mother was Ada Hawes (b. 1878), a high school teacher and social worker, born in Georgia. William and Ada married in 1909, and had two daughters, Jane and Ann Hinton Jones. As a child, Jane attended school in Europe, where her parents believed she would have the best education available as a black student. She returned to the United States to complete high school at Montpelier Seminary in Vermont in 1935, before earning her undergraduate degree at the age of 20 from
Simmons College Institutions of learning called Simmons College or Simmons University include: * Simmons University Simmons University (previously Simmons College) is a private university in Boston, Massachusetts, United States. It was established in 1899 by ...
in 1939.


Career

Prior to her veterinary career, Jane Hinton worked in a laboratory in the Department of Bacteriology and Immunology at Harvard University, where she co-developed the
Mueller–Hinton agar Mueller Hinton agar is a type of growth medium used in microbiology to culture bacterial isolates and test their susceptibility to antibiotics. This medium was first developed in 1941 by John Howard Mueller and Jane Hinton, who were microbiologis ...
with
John Howard Mueller John Howard Mueller (June 13, 1891, Sheffield, Massachusetts – February 14, 1954) was an American biochemist, pathologist, and bacteriologist. He is known as the discoverer of the amino acid methionine in 1921, and as the co-developer, with Jane ...
. This agar was a medium developed to isolate the
Neisseria ''Neisseria'' is a large genus of bacteria that colonize the mucous membranes of many animals. Of the 11 species that colonize humans, only two are pathogens: '' N. meningitidis'' and '' N. gonorrhoeae''. ''Neisseria'' species are Gram-negative ...
bacteria that caused
gonorrhea Gonorrhoea or gonorrhea, colloquially known as the clap, is a sexually transmitted infection (STI) caused by the bacterium ''Neisseria gonorrhoeae''. Infection may involve the genitals, mouth, or rectum. Gonorrhea is spread through sexual c ...
and meningogoccal meningitis. Mueller and Hinton discovered that
starch Starch or amylum is a polymeric carbohydrate consisting of numerous glucose units joined by glycosidic bonds. This polysaccharide is produced by most green plants for energy storage. Worldwide, it is the most common carbohydrate in human diet ...
within the agar helped aid bacterial growth and prevented bacteria toxins from interfering with antibiotic testing. It became the most widely used
culture medium A growth medium or culture medium is a solid, liquid, or semi-solid designed to support the growth of a population of microorganisms or cells via the process of cell proliferation or small plants like the moss '' Physcomitrella patens''. Diffe ...
for Neisseria. In the 1960s, tests indicated its suitability for detecting whether bacteria are susceptible to antibiotics. The
Clinical and Laboratory Standards Institute The Clinical and Laboratory Standards Institute (CLSI) is a volunteer-driven, membership-supported, not-for-profit, standards development organization. CLSI promotes the development and use of voluntary laboratory consensus standards and guidelin ...
, which establishes the best international laboratory standards, adopted the Kirby–Bauer technique using Mueller–Hinton agar as the
gold standard A gold standard is a backed currency, monetary system in which the standard economics, economic unit of account is based on a fixed quantity of gold. The gold standard was the basis for the international monetary system from the 1870s to the ...
for antibiotic testing. During World War II, Hinton also worked as a lab technician in Arizona. After the War, Hinton studied veterinary medicine at the
University of Pennsylvania The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of f ...
, gaining her
Doctor of Veterinary Medicine Doctor, Doctors, The Doctor or The Doctors may refer to: Titles and occupations * Physician, a medical practitioner * Doctor (title), an academic title for the holder of a doctoral-level degree ** Doctorate ** List of doctoral degrees awarded ...
(VMD) degree in 1949. She and Alfreda Johnson Webb, who graduated with a VMD from the Tuskegee Institute (now
Tuskegee University Tuskegee University (Tuskegee or TU; formerly known as the Tuskegee Institute) is a private, historically black land-grant university in Tuskegee, Alabama, United States. It was founded as a normal school for teachers on July 4, 1881, by the ...
) that year, were the first African-American women veterinarians. There had been only four African-American VMD graduates at the University of Pennsylvania before Hinton gained her degree, and there would not be another until 1968. Hinton and Webb were also the first African-American members of the Women's Veterinary Medicine Association. After gaining her degree, Hinton practiced as a small animal veterinarian in
Canton, Massachusetts Canton is a town in Norfolk County, Massachusetts, United States. The population was 24,370 at the 2020 United States census, 2020 census. Canton is part of Greater Boston, about southwest of Downtown Boston. History The area that is present ...
, and then a federal government inspector in
Framingham, Massachusetts Framingham () is a city in the Commonwealth (U.S. state), Commonwealth of Massachusetts, United States. Incorporated in 1700, it is located in Middlesex County, Massachusetts, Middlesex County and the MetroWest subregion of the Greater Boston ...
, where she worked to combat disease outbreaks in livestock. Jane Hinton, together with John Taylor, the first African-American graduate of the University of Pennsylvania veterinary medicine school, were honored during the school's centennial celebrations by the Minority Veterinary Students association in 1984. Jane Hinton retired in 1960 and died at the age of 84 on April 9, 2003.


References

{{DEFAULTSORT:Hinton, Jane 1919 births 2003 deaths 21st-century African-American scientists African-American women academics African-American women scientists 20th-century African-American academics 20th-century American academics University of Pennsylvania School of Veterinary Medicine alumni American veterinarians 20th-century African-American women 20th-century American people 21st-century African-American people 21st-century African-American women Harvard University staff 20th-century African-American scientists 20th-century American women academics