James Lorrain Smith FRS

FRSE Fellowship of the Royal Society of Edinburgh (FRSE) is an award granted to individuals that the Royal Society of Edinburgh, Scotland's national academy of science and Literature, letters, judged to be "eminently distinguished in their subject". ...

FRCPE (21 August 1862 – 18 April 1931) was a Scottish

pathologist Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...

known for his works in human

physiology Physiology (; ) is the science, scientific study of function (biology), functions and mechanism (biology), mechanisms in a life, living system. As a branches of science, subdiscipline of biology, physiology focuses on how organisms, organ syst ...

, especially his research on respiration in collaboration with

John Scott Haldane John Scott Haldane (; 2 May 1860 – 14/15 March 1936) was a Scottish physician physiologist and philosopher famous for intrepid self-experimentation which led to many important discoveries about the human body and the nature of gases. He al ...

Life

He was born in the manse at Half Morton in rural

Dumfriesshire Dumfriesshire or the County of Dumfries or Shire of Dumfries () is a Counties of Scotland, historic county and registration county in southern Scotland. The Dumfries lieutenancy areas of Scotland, lieutenancy area covers a similar area to the hi ...

the fourth son of Rev Walter Smith who was a Free Church of Scotland minister in the parish. He had several talented siblings, including the

mycologist Mycology is the branch of biology concerned with the study of fungi, including their taxonomy, genetics, biochemical properties, and use by humans. Fungi can be a source of tinder, food, traditional medicine, as well as entheogens, poison, and ...

Annie Lorrain Smith, who worked informally at the British Museum. His brother Walter Smith became a professor of philosophy at

Lake Forest College Lake Forest College is a Private college, private Liberal arts colleges in the United States, liberal arts college in Lake Forest, Illinois. Founded in 1857 as Lind University by a group of Presbyterian ministers, the college has been coeducatio ...

Illinois Illinois ( ) is a U.S. state, state in the Midwestern United States, Midwestern United States. It borders on Lake Michigan to its northeast, the Mississippi River to its west, and the Wabash River, Wabash and Ohio River, Ohio rivers to its ...

whilst another brother, William George Smith, became a lecturer in psychology. Lorrain Smith was educated locally then at

George Watson's College George Watson's College is a co-educational Private schools in the United Kingdom, private day school in Scotland, situated on Colinton Road, in the Merchiston area of Edinburgh. It was first established as a Scottish education in the eighteenth ...

Edinburgh Edinburgh is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. The city is located in southeast Scotland and is bounded to the north by the Firth of Forth and to the south by the Pentland Hills. Edinburgh ...

. He studied for a general Arts, graduating with an MA in 1893 and allowing him to then study medicine at the

University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...

where he graduated with an MB ChB in 1889. He then studied

pathology Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...

as a postgraduate under Prof John Lucas Walker at the

University of Cambridge The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, wo ...

. He became a Demonstrator under Professor Charles Smart Roy who recommended that he follow his studies at the universities of

Strasbourg Strasbourg ( , ; ; ) is the Prefectures in France, prefecture and largest city of the Grand Est Regions of France, region of Geography of France, eastern France, in the historic region of Alsace. It is the prefecture of the Bas-Rhin Departmen ...

under

Friedrich Daniel von Recklinghausen Friedrich Daniel von Recklinghausen (; December 2, 1833 – August 26, 1910) was a German pathologist born in Gütersloh, Westphalia. He was the father of physiologist Heinrich von Recklinghausen (1867–1942). Early life Recklinghausen was bo ...

. He spent some time at

Copenhagen Copenhagen ( ) is the capital and most populous city of Denmark, with a population of 1.4 million in the Urban area of Copenhagen, urban area. The city is situated on the islands of Zealand and Amager, separated from Malmö, Sweden, by the ...

where he studied techniques for analysing gases in blood in Christian Bohr's laboratory before moving to teach at the

Queen's College, Belfast The Queen's University of Belfast, commonly known as Queen's University Belfast (; abbreviated Queen's or QUB), is a public research university in Belfast, Northern Ireland, United Kingdom. The university received its charter in 1845 as part of ...

, becoming a professor in 1901. In 1904 he was elected President of the Ulster Medical Association. In 1904 he became Professor of Pathology at the

University of Manchester The University of Manchester is a public university, public research university in Manchester, England. The main campus is south of Manchester city centre, Manchester City Centre on Wilmslow Road, Oxford Road. The University of Manchester is c ...

and in 1912 moved to the

to replace Prof William Smith Greenfield. In 1913 he was elected a member of the

Harveian Society of Edinburgh The Harveian Society of Edinburgh was founded in April 1782 by Andrew Duncan (physician, born 1744), Andrew Duncan. The Society holds an annual Festival in honour of the life and works of William Harvey, the physician who first correctly des ...

. During the

First World War World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...

he helped to introduce the antiseptic " Eusol" (Edinburgh University Solution) and suggested the idea of using charcoal in gas masks. Lorrain Smith worked with

respiration Respiration may refer to: Biology * Cellular respiration, the process in which nutrients are converted into useful energy in a cell ** Anaerobic respiration, cellular respiration without oxygen ** Maintenance respiration, the amount of cellul ...

particularly the transport of

oxygen Oxygen is a chemical element; it has chemical symbol, symbol O and atomic number 8. It is a member of the chalcogen group (periodic table), group in the periodic table, a highly reactivity (chemistry), reactive nonmetal (chemistry), non ...

by the

blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...

. The pulmonary condition of intoxication due to excess oxygen or

oxygen toxicity Oxygen toxicity is a condition resulting from the harmful effects of breathing molecular oxygen () at increased partial pressures. Severe cases can result in cell damage and death, with effects most often seen in the central nervous system, lung ...

is sometimes called " Lorrain Smith effect". He was elected a Fellow of the

Royal Society of London The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, r ...

on 6 May 1909. In 1919 he was elected a Fellow of the

Royal Society of Edinburgh The Royal Society of Edinburgh (RSE) is Scotland's national academy of science and letters. It is a registered charity that operates on a wholly independent and non-partisan basis and provides public benefit throughout Scotland. It was establis ...

. His proposers were Sir William Turner,

Cargill Gilston Knott Cargill Gilston Knott FRS, FRSE LLD (30 June 1856 – 26 October 1922) was a Scottish physicist and mathematician who was a pioneer in seismological research. He spent his early career in Japan. He later became a Fellow of the Royal Society, ...

, Sir Edmund Taylor Whittaker and Arthur Robinson. He died on 18 April 1931. A memorial ceremony was held at the University of Edinburgh read by Principal David Cairns. He was cremated at Warriston Crematorium.

Family

In 1895 he married Isabella Edmond.

Publications

References

{{DEFAULTSORT:Smith, James Lorrain 1862 births 1931 deaths People from Dumfries and Galloway Alumni of the University of Edinburgh University of Strasbourg alumni University of Copenhagen alumni Academics of Queen's University Belfast Scottish pathologists Fellows of the Royal Society People educated at George Watson's College Fellows of the Royal Society of Edinburgh Members of the Harveian Society of Edinburgh