James J. Champoux (died 13 May 2019) was an American microbiologist who worked at

University of Washington The University of Washington (UW and informally U-Dub or U Dub) is a public research university in Seattle, Washington, United States. Founded in 1861, the University of Washington is one of the oldest universities on the West Coast of the Uni ...

and an Elected Fellow of the

American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is a United States–based international nonprofit with the stated mission of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsib ...

Education

He earned his B.S. at University of Washington and his Ph.D. at

Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...

Research

His interests were retroviruses and topoisomerases and his highest cited paper is ''DNA Topoisomerases: Structure, Function, and Mechanism'' at 2260 times, according to Google Scholar.

Publications

*Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1. Interthal H, Champoux JJ The Biochemical Journal. 2011 Jun; 436 3: 559-66 *Multiple nucleotide preferences determine cleavage-site recognition by the HIV-1 and M-MuLV RNases H. Schultz SJ, Zhang M, Champoux JJ Journal of Molecular Biology. 2010 Mar; 397 1: 161-78 *Preferred sequences within a defined cleavage window specify DNA 3' end-directed cleavages by retroviral RNases H. Schultz SJ, Zhang M, Champoux JJ The Journal of Biological Chemistry. 2009 Nov; 284 47: 32225-38 *Assays for the preferential binding of human topoisomerase I to supercoiled DNA. Yang Z, Champoux JJ Methods in Molecular Biology. 2009 ; 582 : 49-57 *Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA. Yang Z, Carey JF, Champoux JJ The FEBS journal. 2009 Oct; 276 20: 5906-19

References

{{DEFAULTSORT:Champoux, James Year of birth missing (living people) Living people Fellows of the American Association for the Advancement of Science University of Washington faculty American microbiologists