Jakob Erdheim (24 May 1874,
Boryslav
Boryslav ( uk, Борислав; pl, Borysław) is a city located on the Tysmenytsia (a tributary of the Dniester), in Drohobych Raion, Lviv Oblast (region) of western Ukraine. It hosts the administration of Boryslav urban hromada, one of the ...
,
Galicia
Galicia may refer to:
Geographic regions
* Galicia (Spain), a region and autonomous community of northwestern Spain
** Gallaecia, a Roman province
** The post-Roman Kingdom of the Suebi, also called the Kingdom of Gallaecia
** The medieval King ...
– 18 April 1937,
Vienna
en, Viennese
, iso_code = AT-9
, registration_plate = W
, postal_code_type = Postal code
, postal_code =
, timezone = CET
, utc_offset = +1
, timezone_DST ...
) was an Austrian
pathologist
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in t ...
.
[Österreichisches Biographisches Lexikon 1815-1950]
(biography in German) He is credited with the characterization (or partial characterization) of
Erdheim–Chester disease
Erdheim–Chester disease (ECD) is an extremely rare disease characterized by the abnormal multiplication of a specific type of white blood cells called histiocytes, or tissue macrophages (technically, this disease is termed a non- Langerhans-c ...
and
cystic medial necrosis.
He was born into a Jewish family in Boryslav. In 1901 he received his medical doctorate from the
University of Vienna
The University of Vienna (german: Universität Wien) is a public research university located in Vienna, Austria. It was founded by Duke Rudolph IV in 1365 and is the oldest university in the German-speaking world. With its long and rich h ...
, later working as an assistant at the institute of
pathological anatomy
Anatomical pathology (''Commonwealth'') or Anatomic pathology (''U.S.'') is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination o ...
in Vienna. In 1913 he became habilitated for pathological anatomy, and in 1916 was named director of the pathological-anatomical institute at Vienna city hospital.
[Jakob Erdheim]
@ Who Named It
''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliograp ...
From 1924 onward, he was associated with the "Krankenhaus der Stadt Wien-Lainz".
[
He distinguished himself in research of ]hyperparathyroidism
Hyperparathyroidism is an increase in parathyroid hormone (PTH) levels in the blood. This occurs from a disorder either within the parathyroid glands ( primary hyperparathyroidism) or as response to external stimuli (secondary hyperparathyroidis ...
, acromegaly
Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. There may also be an enlargement of the forehead, jaw, and nose. Othe ...
, Paget’s disease and pituitary gland
In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland, about the size of a chickpea and weighing, on average, in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain. The hypop ...
abnormalities. His name is associated with "Erdheim's syndrome", a condition that is also known as "Scaglietti-Dagnini syndrome" (cervical spondylosis
Spondylosis is the degeneration of the vertebral column from any cause. In the more narrow sense it refers to spinal osteoarthritis, the age-related wear and tear of the spinal column, which is the most common cause of spondylosis. The degenera ...
secondary to acromegaly). Other eponyms associated with him are:
* Erdheim disease: a synonym for cystic medial necrosis.
* Erdheim tumor: a synonym for craniopharyngioma
A craniopharyngioma is a rare type of brain tumor derived from pituitary gland embryonic tissue that occurs most commonly in children, but also affects adults. It may present at any age, even in the prenatal and neonatal periods, but peak incidence ...
.
He used the term "nanosomia pituitaria" to describe pituitary dwarfism.[
]
Published works
* ''Uber Hypophysenganggeschwülste und Hirncholesteatome'', 1904 - On pituitary swelling and brain cholesteatoma
Cholesteatoma is a destructive and expanding growth consisting of keratinizing squamous epithelium in the middle ear and/or mastoid process. Cholesteatomas are not cancerous as the name may suggest, but can cause significant problems because of the ...
.
* ''Rachitis und Epithelkörperchen'', 1914 - Rachitis and the parathyroid gland
Parathyroid glands are small endocrine glands in the neck of humans and other tetrapods. Humans usually have four parathyroid glands, located on the back of the thyroid gland in variable locations. The parathyroid gland produces and secretes ...
s.
* ''Die lebensvorgange im normalen knorpel und seine wucherung bei akromegalie'', 1931 - Life processes of normal cartilage and its growth in acromegalia.WorldCat Identities
(publications)
References
External links
*
{{DEFAULTSORT:Erdheim, Jakob
1874 births
1937 deaths
Austrian pathologists
People from Boryslav
People from the Kingdom of Galicia and Lodomeria
Jews from Galicia (Eastern Europe)
Austro-Hungarian Jews
Austrian Jews