Sir Jack Martin Cuzick (born 11 August 1948) is an American-born British academic, director of the Wolfson Institute of Preventive Medicine in London and head of the Centre for Cancer Prevention. He is the John Snow Professor of Epidemiology at the Wolfson Institute,

Queen Mary University of London Queen Mary University of London (QMUL, or informally QM, and formerly Queen Mary and Westfield College) is a public university, public research university in Mile End, East London, England. It is a member institution of the federal University ...

Education and early life

Cuzick was born in

Hawthorne, California Hawthorne is a city in southwestern Los Angeles County, California. It is part of a seventeen-city subregion of the Los Angeles metropolitan area commonly known as the South Bay (Los Angeles County), South Bay. As of the 2020 United States cens ...

and attended

El Segundo High School El Segundo High School, or ESHS, is a four-year public high school located in El Segundo, California. It is the only secondary school incorporated by El Segundo Unified School District. First built in 1927, the school campus contains 5 main buil ...

. He earned a BS degree in mathematics and physics from

Harvey Mudd College Harvey Mudd College (HMC) is a private liberal arts college in Claremont, California, focused on science and engineering. It is part of the Claremont Colleges, which share adjoining campus grounds and resources. The college enrolled 902 undergra ...

in 1970, and a PhD in mathematics from

Claremont Graduate School The Claremont Graduate University (CGU) is a private, all-graduate research university in Claremont, California, United States. Founded in 1925, CGU is a member of the Claremont Colleges consortium which includes five undergraduate and two grad ...

in 1974.

Research and career

He worked on the mathematical analysis of clinical trial methodology at

Columbia University Columbia University in the City of New York, commonly referred to as Columbia University, is a Private university, private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Churc ...

in New York City in the late 1970s and moved to

Oxford University The University of Oxford is a collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the second-oldest continuously operating u ...

in 1978 to work with cancer epidemiologist Richard Doll. He is involved in the collection and analysis of data for cancer prevention and screening, particularly for breast, cervical and

bowel cancer Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel ...

s. He is best known for his role conducting the IBIS trials of

tamoxifen Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men. It is also being studied for other types of cancer. It has been used for Albright syndrome ...

and

aromatase inhibitors Aromatase inhibitors (AIs) are a class of medication, drugs used in the treatment of breast cancer in menopause, postmenopausal women and in men, and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when suppleme ...

for chemoprevention of breast cancer in women with high risk of developing the disease. For this research, Cuzick's team won

Cancer Research UK Cancer Research UK (CRUK) is the world's largest independent cancer research organisation. It is registered as a charity in the United Kingdom and Isle of Man, and was formed on 4 February 2002 by the merger of The Cancer Research Campaign and t ...

's Translational Cancer Research Prize in 2014,

Honours and awards

* 2025 Received a Knighthood in The King’s New Year Honours list 2025 * 2017 Cancer Research UK Lifetime Achievement in Cancer Research Prize * 2016 Elected Fellow of the Royal Society. * 2015 Cuzick received the

American Cancer Society The American Cancer Society (ACS) is a nationwide non-profit organization dedicated to eliminating cancer. The ACS publishes the journals ''Cancer'', '' CA: A Cancer Journal for Clinicians'' and '' Cancer Cytopathology''. History The society w ...

Medal of Honor. * 2014 Cancer Research UK Translational Cancer Research Team Prize * 2003 Elected Fellow of the

Academy of Medical Sciences The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academy, National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its ...

* Cuzick was appointed

Commander of the Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two o ...

(CBE) in the

2017 New Year Honours The 2017 New Year Honours are appointments by some of the 16 Commonwealth realms to various orders and honours to recognise and reward good works by citizens of those countries. The New Year Honours were awarded as part of the New Year celebrati ...

for services to cancer prevention and screening.

References

External links

* 1948 births Living people People from Hawthorne, California Cancer epidemiologists British medical researchers Academics of Queen Mary University of London Fellows of the Royal Society Commanders of the Order of the British Empire El Segundo High School alumni Naturalised citizens of the United Kingdom Harvey Mudd College alumni Knights Bachelor {{UK-med-bio-stub