Transcription factor jun-B is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that, in humans, is encoded by the ''JUNB''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Transcription factor jun-B is a
transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription (genetics), transcription of genetics, genetic information from DNA to messenger RNA, by binding t ...
involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA
GCA-3'.
Interactions
JUNB has been shown to
interact with
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BRCA1,
and
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SMAD3.
See also
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AP-1 (transcription factor)
References
Further reading
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External links
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Transcription factors
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