JT-010 is a chemical compound which acts as a potent, selective activator of the
TRPA1
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Wasabi Receptor, is a protein that in humans is encoded by the ''TRPA1'' (and in mice and rats by the ''Trpa1' ...
channel, and has been used to study the role of this receptor in the perception of
pain
Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, ...
, as well as other actions such as promoting repair of dental tissue after damage.
See also
*
ASP-7663
*
PF-4840154
References
{{Transient receptor potential channel modulators
Nitrogen mustards
Thiazoles
Amides
Phenyl compounds
Ethers
Transient receptor potential channel agonists