Ivar Karl Ugi (9 September 1930 in

Saaremaa Saaremaa is the largest island in Estonia, measuring . The main island of Saare County, it is located in the Baltic Sea, south of Hiiumaa island and west of Muhu island, and belongs to the West Estonian Archipelago. The capital of the islan ...

Estonia Estonia, formally the Republic of Estonia, is a country by the Baltic Sea in Northern Europe. It is bordered to the north by the Gulf of Finland across from Finland, to the west by the sea across from Sweden, to the south by Latvia, and t ...

– 29 September 2005 in

Munich Munich ( ; german: München ; bar, Minga ) is the capital and most populous city of the German state of Bavaria. With a population of 1,558,395 inhabitants as of 31 July 2020, it is the third-largest city in Germany, after Berlin and Ha ...

) was an

n-born German

chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe ...

who made major contributions to

organic chemistry Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clay ...

. He is known for the research on multicomponent reactions, yielding the Ugi reaction.

Biography

After he went to Germany from Estonia in 1941 he began his studies of chemistry in 1949 at the

University of Tübingen The University of Tübingen, officially the Eberhard Karl University of Tübingen (german: Eberhard Karls Universität Tübingen; la, Universitas Eberhardina Carolina), is a public research university located in the city of Tübingen, Baden-W� ...

until 1951. He became Dr. rer. nat. in 1954 at the

Ludwig Maximilian University of Munich The Ludwig Maximilian University of Munich (simply University of Munich or LMU; german: link=no, Ludwig-Maximilians-Universität München) is a public research university in Munich, Bavaria, Germany. Originally established as the University of ...

. He did his habilitation 1960 at the same university. After a short but very successful career in industry at

Bayer Bayer AG (, commonly pronounced ; ) is a German multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include pharmaceutica ...

from 1962 until 1968 when he joined the

University of Southern California , mottoeng = "Let whoever earns the palm bear it" , religious_affiliation = Nonsectarian—historically Methodist , established = , accreditation = WSCUC , type = Private research university , academic_affiliations = , endowment = $8. ...

at Los Angeles. From 1971 he worked at the

Technical University of Munich The Technical University of Munich (TUM or TU Munich; german: Technische Universität München) is a public research university in Munich, Germany. It specializes in engineering, technology, medicine, and applied and natural sciences. Establis ...

, and was an emeritus from 1999 until his death in 2005.

Research and development

The one pot reaction of a

ketone In organic chemistry, a ketone is a functional group with the structure R–C(=O)–R', where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group –C(=O)– (which contains a carbon-oxygen double bon ...

aldehyde In organic chemistry, an aldehyde () is an organic compound containing a functional group with the structure . The functional group itself (without the "R" side chain) can be referred to as an aldehyde but can also be classified as a formyl group ...

, an

amine In chemistry, amines (, ) are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (), wherein one or more hydrogen atoms have been replaced by a substituent su ...

, an

isocyanide An isocyanide (also called isonitrile or carbylamine) is an organic compound with the functional group –. It is the isomer of the related nitrile (–C≡N), hence the prefix is ''isocyano''.IUPAC Goldboo''isocyanides''/ref> The organic fra ...

and a

carboxylic acid In organic chemistry, a carboxylic acid is an organic acid that contains a carboxyl group () attached to an R-group. The general formula of a carboxylic acid is or , with R referring to the alkyl, alkenyl, aryl, or other group. Carboxyl ...

to form a bis-

amide In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula , where R, R', and R″ represent organic groups or hydrogen atoms. The amide group is called a peptide bond when it is ...

is generally known as Ugi reaction.

Major works

References

Curriculum Vitae at TUM
* {{DEFAULTSORT:Ugi, Ivar Karl 1930 births 2005 deaths People from Kuressaare 20th-century German chemists Estonian chemists Organic chemists University of Tübingen alumni Ludwig Maximilian University of Munich alumni University of Southern California faculty Technical University of Munich faculty Members of the Estonian Academy of Sciences Estonian emigrants to Germany Estonian expatriates in Germany Estonian World War II refugees Recipients of the Order of the White Star, 4th Class