In Muller's classification, an isomorph is described as a
gene mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis ...
that expresses a
nonsense
Nonsense is a form of communication, via speech, writing, or any other formal logic system, that lacks any coherent meaning. In ordinary usage, nonsense is sometimes synonymous with absurdity or the ridiculous. Many poets, novelists and songwri ...
point mutant, with
expression identical to the original
allele
An allele is a variant of the sequence of nucleotides at a particular location, or Locus (genetics), locus, on a DNA molecule.
Alleles can differ at a single position through Single-nucleotide polymorphism, single nucleotide polymorphisms (SNP), ...
.
Therefore, in respect to the relationships between the original and mutated genes, it is difficult to ascertain the effects of
dominanceness and/or
recessiveness.
;Muller's classification of mutant alleles
See also
*
Allele
An allele is a variant of the sequence of nucleotides at a particular location, or Locus (genetics), locus, on a DNA molecule.
Alleles can differ at a single position through Single-nucleotide polymorphism, single nucleotide polymorphisms (SNP), ...
*
Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, ...
*
Muller's morphs
Hermann J. Muller (1890–1967), who was a 1946 Nobel Prize winner, coined the terms amorph, hypomorph, hypermorph, antimorph and neomorph to classify mutations based on their behaviour in various genetic situations, as well as gene interac ...
References
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Mutation