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Isocoumarin (1''H''-2-benzopyran-1-one; 3,4-benzo-2-pyrone) is a
lactone Lactones are cyclic carboxylic esters, containing a 1-oxacycloalkan-2-one structure (), or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. Lactones are formed by intramolecular esterification of the co ...
, a type of natural organic compound.


Known natural compounds

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Thunberginol A Thunberginol A is an isocoumarin found in '' Hydrangea macrophylla'' and the herbal preparation ''hydrangeae dulcis folium'' which is produced from its leaves. References Isocoumarins {{phenol-stub ...
and B ; dihydroisocoumarins *
Hydrangenol Hydrangenol is a dihydroisocoumarin Dihydroisocoumarins are phenolic compounds related to isocoumarin. Dihydroisocoumarin glucosides can be found in ''Caryocar glabrum ''Caryocar glabrum'' is a species of tree in the family Caryocaraceae. It ...
*
Phyllodulcin Phyllodulcin is a dihydroisocoumarin found in '' Hydrangea macrophylla'' and '' Hydrangea serrata''.Accumulation of phyllodulcin in sweet-leaf plants of Hydrangea serrata and its neutrality in the defence against a specialist leafmining herbivore ...
*
Thunberginol C Thunberginol C is a dihydroisocoumarin found in ''Hydrangeae Dulcis Folium'', the processed leaves of ''Hydrangea macrophylla ''Hydrangea macrophylla'' is a species of flowering plant in the family Hydrangeaceae, native to Japan. It is a decidu ...
, D, E and G * The
derivative In mathematics, the derivative of a function of a real variable measures the sensitivity to change of the function value (output value) with respect to a change in its argument (input value). Derivatives are a fundamental tool of calculus. ...
3-acetyl-3,4-dihydro-5,6-dimethoxy-1''H''-2-benzopyran-1-one can be found in
Huáng bǎi Huáng bǎi (黃 栢 ''or'' 黃 栢, literally "yellow fir"), huáng bó (黃柏) or huáng bò (黃 檗) is one of the fifty fundamental herbs of traditional Chinese medicine. Known also as Cortex Phellodendri, it is the bark of one of two speci ...
(''
Phellodendron chinense ''Phellodendron chinense'' is a plant species in the genus ''Phellodendron''. The isocoumarin derivative In mathematics, the derivative of a function of a real variable measures the sensitivity to change of the function value (output va ...
''), one of the fifty fundamental herbs of traditional Chinese medicine.


See also

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Coumarin Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered ...


References

{{heterocyclic-stub