Isaiah Johnson may refer to:
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Isaiah Johnson (American football, born May 1992), NFL safety who played college at Georgia Tech
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Isaiah Johnson (American football, born October 1992), NFL safety who played college at Kansas and South Carolina
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Isaiah Johnson (cornerback, born December 1995), NFL cornerback who played college at Houston
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Isaiah Johnson (cornerback, born March 2000), NFL cornerback who played college at Syracuse and Dartmouth
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Isaiah Johnson (basketball) (born 1994), American basketball player
{{hndis, Johnson, Isaiah