''Iotapapillomavirus'' is a genus of
viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almo ...
in the family ''
Papillomaviridae
''Papillomaviridae'' is a family of non- enveloped double-stranded DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all car ...
''.
Rodents serve as natural hosts. There are two species in this genus. Diseases associated with this genus include cutaneous lesions and benign skin tumours, such as
papillomas and
keratoacanthomas.
Taxonomy
The following two species are assigned to the genus:
* ''
Iotapapillomavirus 1''
* ''
Iotapapillomavirus 2''
Structure
Viruses in ''Iotapapillomavirus'' are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length.
Life cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown.
Rodents serve as the natural host. Transmission routes are contact.
References
External links
ICTV Report ''Papillomaviridae''
{{Taxonbar, from=Q18819939
Papillomavirus
Virus genera