In
anatomy
Anatomy () is the branch of morphology concerned with the study of the internal structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old scien ...
and
physiology
Physiology (; ) is the science, scientific study of function (biology), functions and mechanism (biology), mechanisms in a life, living system. As a branches of science, subdiscipline of biology, physiology focuses on how organisms, organ syst ...
, a duct is a circumscribed channel leading from an
exocrine gland
Exocrine glands are glands that secrete substances onto an epithelial surface by way of a duct. Examples of exocrine glands include sweat, salivary, mammary, ceruminous, lacrimal, sebaceous, prostate and mucous. Exocrine glands are one of ...
or
organ
Organ and organs may refer to:
Biology
* Organ (biology), a group of tissues organized to serve a common function
* Organ system, a collection of organs that function together to carry out specific functions within the body.
Musical instruments
...
.
Types of ducts
Examples include:
Duct system
As ducts travel from the
acinus
An acinus (; : acini; adjective, acinar or acinous) refers to any cluster of cells that resembles a many-lobed "berry", such as a raspberry ('' acinus'' is Latin for "berry"). The berry-shaped termination of an exocrine gland, where the secr ...
which generates the fluid to the target, the ducts become larger and the epithelium becomes thicker. The parts of the system are classified as follows:
Some sources consider "lobar" ducts to be the same as "interlobar ducts", while others consider lobar ducts to be larger and more distal from the acinus. For sources that make the distinction, the interlobar ducts are more likely to classified with
simple columnar epithelium
Simple columnar epithelium is a single layer of columnar epithelial cells which are tall and slender with oval-shaped nuclei located in the basal region, attached to the basement membrane. In humans, simple columnar epithelium lines most organs ...
(or
pseudostratified epithelium
Pseudostratified columnar epithelium is a type of epithelium that, though comprising only a single layer of cells, has its cell nuclei positioned in a manner suggestive of stratified columnar epithelium. A stratified epithelium rarely occurs a ...
), reserving the stratified columnar for the lobar ducts.
File:Gray1025.png, Section of submaxillary gland
The paired submandibular glands (historically known as submaxillary glands) are major salivary glands located beneath the floor of the mouth. In adult humans, they each weigh about 15 grams and contribute some 60–67% of unstimulated saliva sec ...
of kitten
A kitten is a Juvenile (organism), juvenile cat. After being born, kittens display primary altriciality and are fully dependent on their mothers for #Establishing immunity, survival. They normally do not open their eyes for seven to ten days. A ...
. Duct semidiagrammatic. X 200.
File:Gray1173.png, Section of portion of mamma.
Intercalated duct
The intercalated duct, also called intercalary duct (ducts of Boll), is the portion of an
exocrine gland
Exocrine glands are glands that secrete substances onto an epithelial surface by way of a duct. Examples of exocrine glands include sweat, salivary, mammary, ceruminous, lacrimal, sebaceous, prostate and mucous. Exocrine glands are one of ...
leading directly from the
acinus
An acinus (; : acini; adjective, acinar or acinous) refers to any cluster of cells that resembles a many-lobed "berry", such as a raspberry ('' acinus'' is Latin for "berry"). The berry-shaped termination of an exocrine gland, where the secr ...
to a
striated duct. The intercalated duct forms part of the
intralobular duct. This duct has the thinnest epithelium of any part of the duct system, and the epithelium is usually classified as "low"
simple cuboidal
Simple cuboidal epithelium is a type of epithelium that consists of a single layer of cuboidal (cube-like) cells which have large, spherical and central nuclei.
Simple cuboidal epithelium is found on the surface of ovaries, the lining of nephro ...
.
They are found in both the
pancreas
The pancreas (plural pancreases, or pancreata) is an Organ (anatomy), organ of the Digestion, digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity, abdomen behind the stomach and functions as a ...
and in
salivary gland
The salivary glands in many vertebrates including mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands ( parotid, submandibular, and sublingual), as well as hundreds of min ...
s.
Striated duct

A striated duct (Pflüger's ducts) is a
gland
A gland is a Cell (biology), cell or an Organ (biology), organ in an animal's body that produces and secretes different substances that the organism needs, either into the bloodstream or into a body cavity or outer surface. A gland may also funct ...
duct which connects an
intercalated duct
In anatomy and physiology, a duct is a circumscribed channel leading from an exocrine gland or organ.
Types of ducts
Examples include:
Duct system
As ducts travel from the acinus which generates the fluid to the target, the ducts become large ...
to an interlobular duct. It is characterized by the basal infoldings of its plasma membrane, characteristic of ion-pumping activity by the numerous mitochondria. Along with the intercalated ducts, they function to modify salivary fluid by secreting HCO
3− and K
+ and reabsorbing Na
+ and Cl
− using the Na-K pump and the Cl-HCO
3 pump, making the saliva hypotonic.
Their
epithelium
Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis, the outermost layer of the skin. Epithelial ( mesothelial) tissues line the outer surfaces of man ...
can be
simple cuboidal
Simple cuboidal epithelium is a type of epithelium that consists of a single layer of cuboidal (cube-like) cells which have large, spherical and central nuclei.
Simple cuboidal epithelium is found on the surface of ovaries, the lining of nephro ...
or
simple columnar.
Striated ducts are part of the
intralobular ducts.
They are found in the
submandibular gland
The paired submandibular glands (historically known as submaxillary glands) are major salivary glands located beneath the floor of the mouth. In adult humans, they each weigh about 15 grams and contribute some 60–67% of unstimulated saliva sec ...
,
sublingual duct, and the
parotid gland
The parotid gland is a major salivary gland in many animals. In humans, the two parotid glands are present on either side of the mouth and in front of both ears. They are the largest of the salivary glands. Each parotid is wrapped around the m ...
, but are more developed in the parotid gland.
They are not present in
pancreas
The pancreas (plural pancreases, or pancreata) is an Organ (anatomy), organ of the Digestion, digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity, abdomen behind the stomach and functions as a ...
.
Intralobular duct
An intralobular duct is the portion of an
exocrine gland
Exocrine glands are glands that secrete substances onto an epithelial surface by way of a duct. Examples of exocrine glands include sweat, salivary, mammary, ceruminous, lacrimal, sebaceous, prostate and mucous. Exocrine glands are one of ...
inside a
lobule
In anatomy, a lobe is a clear anatomical division or extension of an organ (as seen for example in the brain, lung, liver, or kidney) that can be determined without the use of a microscope at the gross anatomy level. This is in contrast to the mu ...
, leading directly from
acinus
An acinus (; : acini; adjective, acinar or acinous) refers to any cluster of cells that resembles a many-lobed "berry", such as a raspberry ('' acinus'' is Latin for "berry"). The berry-shaped termination of an exocrine gland, where the secr ...
to an interlobular duct (between lobules). It is composed of two subdivisions, the
intercalated duct
In anatomy and physiology, a duct is a circumscribed channel leading from an exocrine gland or organ.
Types of ducts
Examples include:
Duct system
As ducts travel from the acinus which generates the fluid to the target, the ducts become large ...
and the
striated duct.
In the human mammary gland, the intralobular duct is a part of the glandular system that resides within the lobules. Lobules contain clusters of ducts whose secretory alveolies are drained by the intralobular duct. The intralobular ducts are usually lined with simple cuboidal epithelial cells that are lined by myoepithelial cells as well.
The intralobular ducts of the lobules drain into the interlobular ducts between lobules.
They can be seen in:
*
pancreas
The pancreas (plural pancreases, or pancreata) is an Organ (anatomy), organ of the Digestion, digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity, abdomen behind the stomach and functions as a ...
*
salivary glands
The salivary glands in many vertebrates including mammals are exocrine glands that produce saliva through a system of Duct (anatomy), ducts. Humans have three paired major salivary glands (Parotid gland, parotid, Submandibular gland, submandibula ...
See also
*
Ductal carcinoma
*
Endocrine gland
The endocrine system is a network of glands and organs located throughout the body. Along with the nervous system, it makes the neuroendocrine system, which controls and regulates many of the body's functions. Endocrine glands are ductless gland ...
*
List of distinct cell types in the adult human body
The list of human cell types provides an enumeration and description of the various specialized cells found within the human body, highlighting their distinct functions, characteristics, and contributions to overall physiological processes. Cell ...
References
External links
Overview at uwa.edu.au
{{Authority control
Glands