The interleukin 11 receptor is a
type I cytokine receptor
Type I cytokine receptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines with four α-helical strands. These receptors are also known under the name '' hemopoietin receptors'', and share a ...
, binding
interleukin 11
Interleukin 11 (IL-11 or adipogenesis inhibitory factor) is a protein that in humans is encoded by the ''IL11'' gene.
IL-11 is a cytokine that was first isolated in 1990 from bone marrow-derived fibrocyte-like stromal cells. It was initially th ...
. It is a heterodimer composed of an
interleukin 11 receptor alpha subunit
Interleukin 11 receptor, alpha subunit is a subunit of the interleukin 11 receptor. IL11RA is its human gene.
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 ...
and an incompletely characterized beta subunit.
References
External links
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Type I cytokine receptors
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