The interleukin-31 receptor (IL-31R) is a

receptor Receptor may refer to: * Sensory receptor, in physiology, any neurite structure that, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and respond ...

bound and activated by

interleukin-31 Interleukin-31 (IL-31) is a protein that in humans is encoded by the ''IL31'' gene that resides on chromosome 12. IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a majo ...

(IL-31). It is a

heterodimer In biochemistry, a protein dimer is a macromolecular complex or multimer formed by two protein monomers, or single proteins, which are usually non-covalently bound. Many macromolecules, such as proteins or nucleic acids, form dimers. The word ...

consisting of IL-31 receptor A ( IL31RA) and

oncostatin M receptor Oncostatin-M specific receptor subunit beta also known as the Oncostatin M receptor (OSMR) , is one of the receptor proteins for oncostatin M, that in humans is encoded by the ''OSMR'' gene. OSMR is a member of the type I cytokine receptor famil ...

subunits.

References

Cytokine receptors {{membrane-protein-stub