Integrin alpha-5 is a
protein that in humans is encoded by the ''ITGA5''
gene.
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Interactions
ITGA5 has been shown to
interact
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See also
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Cluster of differentiation
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Integrin
References
Further reading
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External links
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ITGA5Info with links in th
Cell Migration Gateway
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Clusters of differentiation
Integrins
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