The enzyme inositol-polyphosphate 5-phosphatase (), systematic name 1D-''myo''-inositol-1,4,5-trisphosphate 5-phosphohydrolase, catalyses the following reactions: : (1) D-''myo''-inositol 1,4,5-trisphosphate + H₂O

\rightleftharpoons

''myo''-inositol 1,4-bisphosphate +

phosphate Phosphates are the naturally occurring form of the element phosphorus. In chemistry, a phosphate is an anion, salt, functional group or ester derived from a phosphoric acid. It most commonly means orthophosphate, a derivative of orthop ...

: (2) 1D-''myo''-inositol 1,3,4,5-tetrakisphosphate + H₂O

\rightleftharpoons

1D-''myo''-inositol 1,3,4-trisphosphate + phosphate Ten

mammalian A mammal () is a vertebrate animal of the Class (biology), class Mammalia (). Mammals are characterised by the presence of milk-producing mammary glands for feeding their young, a broad neocortex region of the brain, fur or hair, and three ...

isoforms A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene and are the result of genetic differences. While many perform the same or similar biological roles, some isoforms have uniqu ...

are known. Other names of this enzyme include type I inositol-polyphosphate phosphatase, inositol trisphosphate phosphomonoesterase, InsP₃/Ins(1,3,4,5)P₄ 5-phosphatase, inosine triphosphatase, D-''myo''-inositol 1,4,5-triphosphate 5-phosphatase, D-''myo''-inositol 1,4,5-trisphosphate 5-phosphatase, L-''myo''-inositol 1,4,5-trisphosphate-monoesterase'', ''inositol phosphate 5-phosphomonoesterase, inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase, Ins(1,4,5)P₃ 5-phosphataseD-''myo''-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase, inositol 1,4,5-trisphosphate phosphatase, inositol polyphosphate-5-phosphatase, ''myo''-inositol-1,4,5-trisphosphate 5-phosphatase, inositol-1,4,5-trisphosphate 5-phosphatase.

References

External links

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