Ineffective erythropoiesis a condition in which the bone marrow produces red blood cells (

erythrocytes Red blood cells (RBCs), referred to as erythrocytes (, with -''cyte'' translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cel ...

) that are unable to mature properly and are pre-maturely destroyed due to various causes.

Erythropoiesis Erythropoiesis (from Greek ''erythro'', meaning ''red'' and ''poiesis'', meaning ''to make'') is the process which produces red blood cells (erythrocytes), which is the development from erythropoietic stem cell to mature red blood cell. It is s ...

is the overall process that the body goes through to produce red blood cells. The red blood cell's main function is to carry and transport oxygen from the lungs to tissues throughout the body. If the red blood cells are unable to mature properly or are destroyed pre-maturely, this can lead to anemia. This mechanism is principally responsible for the

anemia Anemia (also spelt anaemia in British English) is a blood disorder in which the blood has a reduced ability to carry oxygen. This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin availabl ...

seen in acquired conditions such as certain subtypes of

myelodysplastic syndrome A myelodysplastic syndrome (MDS) is one of a group of cancers in which blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. Early on, no symptoms typically are seen. Later, symptoms may includ ...

(MDS) and inherited disorders such as

β-thalassemia Beta-thalassemia (β-thalassemia) is an inherited blood disorder, a form of thalassemia resulting in variable outcomes ranging from clinically asymptomatic to severe anemia individuals. It is caused by reduced or absent synthesis of the beta ...

, inherited

sideroblastic anemia Sideroblastic anemia, or sideroachrestic anemia, is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). In sideroblastic anemia, the body has iron available but cannot incorpora ...

s, as well as

congenital dyserythropoietic anemia Congenital dyserythropoietic anemia (CDA) is a rare blood disorder, similar to the thalassemias. CDA is one of many types of anemia, characterized by ineffective erythropoiesis, and resulting from a decrease in the number of red blood cells (RBCs) ...

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{{Medical resources , ICD11 = , ICD10 = , ICD10CM = , ICD9 = , ICDO = , OMIM = , MeshID = , DiseasesDB = 6784 , SNOMED CT = 70730006 , Curlie = , MedlinePlus = , eMedicineSubj = , eMedicineTopic = , PatientUK = , NCI = , GeneReviewsNBK = , GeneReviewsName = , NORD = , GARDNum = , GARDName = , RP = , AO = , WO = , OrthoInfo = , Orphanet = , Scholia = Q2380264 , OB = Medical terminology Anemias

See also

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