''Anamirta cocculus'' () is a

Southeast Asia Southeast Asia is the geographical United Nations geoscheme for Asia#South-eastern Asia, southeastern region of Asia, consisting of the regions that are situated south of China, east of the Indian subcontinent, and northwest of the Mainland Au ...

n and Indian

climbing plant A vine is any plant with a growth habit of trailing or scandent (that is, climbing) stems, lianas, or runners. The word ''vine'' can also refer to such stems or runners themselves, for instance, when used in wicker work.Jackson; Benjamin; Da ...

. It is the source of

picrotoxin Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound. It was first isolated by the French pharmacist and chemist Pierre François Guillaume Boullay (1777–1869) in 1812. The name "picrotoxin" is a combination of the Gree ...

, a

poison A poison is any chemical substance that is harmful or lethal to living organisms. The term is used in a wide range of scientific fields and industries, where it is often specifically defined. It may also be applied colloquially or figurati ...

ous compound with stimulant properties. The plant is large-stemmed (up to 10 cm in diameter); the bark is "corky gray" with white wood. The "small, yellowish-white, sweet-scented" flowers vary between 6 and 10 millimeters across; the fruit produced is a

drupe In botany, a drupe (or stone fruit) is a type of fruit in which an outer fleshy part (exocarp, or skin, and mesocarp, or flesh) surrounds a single shell (the ''pip'' (UK), ''pit'' (US), ''stone'', or ''pyrena'') of hardened endocarp with a seed ...

, "about 1 cm in diameter when dry".

Chemical substances

The stem and the roots contain

quaternary The Quaternary ( ) is the current and most recent of the three periods of the Cenozoic Era in the geologic time scale of the International Commission on Stratigraphy (ICS), as well as the current and most recent of the twelve periods of the ...

alkaloid Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large varie ...

s, such as

berberine Berberine is a Quaternary ammonium cation, quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids, occurring naturally as a secondary metabolite in some plants including species of ''Berberis'', from which its name ...

palmatine Palmatine is a protoberberine alkaloid found in several plants including ''Coptis chinensis'' (Rhizoma coptidis, chinese goldthread), ''Corydalis yanhusuo'', ''Tinospora cordifolia'' (gurjo, heart-leaved moonseed), '' Tinospora sagittata'', ''Phel ...

magnoflorine ''(S)-''Magnoflorine is a quaternary benzylisoquinoline alkaloid (BIA) of the aporphine structural subgroup which has been isolated from various species of the family Menispermaceae, such as ''Pachygone ovata,'' '' Sinomenium acutum,'' and '' Ci ...

and columbamine. The seeds deliver

, a

sesquiterpene Sesquiterpenes are a class of terpenes that consist of three isoprene units and often have the molecular formula C15H24. Like monoterpenes, sesquiterpenes may be cyclic or contain rings, including many combinations. Biochemical modifications s ...

, while the seed shells contain the tertiary alkaloids menispermine and paramenispermine.

Uses

Its crushed seeds are an effective

pediculicide The treatment of human lice is the removal of head lice parasites from human hair. It has been debated and studied for centuries. However, the number of cases of human louse infestations (or pediculosis) has increased worldwide since the mid-1960s ...

(anti-

lice Louse (: lice) is the common name for any member of the infraorder Phthiraptera, which contains nearly 5,000 species of wingless parasitic insects. Phthiraptera was previously recognized as an order, until a 2021 genetic study determined th ...

) and are also traditionally used to stun fish or as a

pesticide Pesticides are substances that are used to control pests. They include herbicides, insecticides, nematicides, fungicides, and many others (see table). The most common of these are herbicides, which account for approximately 50% of all p ...

. In

pharmacology Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur betwee ...

, it is known as Cocculus Indicus. Although poisonous, hard multum is a preparation made from ''Cocculus Indicus'', etc., once used (by 19th century brewers) to impart a more intoxicating quality ("giddiness") to

beer Beer is an alcoholic beverage produced by the brewing and fermentation of starches from cereal grain—most commonly malted barley, although wheat, maize (corn), rice, and oats are also used. The grain is mashed to convert starch in the ...

than provided by the alcoholic content alone.

Charles Dickens Charles John Huffam Dickens (; 7 February 1812 – 9 June 1870) was an English novelist, journalist, short story writer and Social criticism, social critic. He created some of literature's best-known fictional characters, and is regarded by ...

referred to those engaging in such practices as "brewers and beer-sellers of low degree,... who do not understand the wholesome policy of selling wholesome beverage." Although appearing in many

homeopathic Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths or homeopathic physicians, believe that a substance tha ...

volumes and at least two brewers' guides, the use of such preparations was outlawed in England, during the mid-19th century, with fines of £500 for sale and £200 for use of the drug. The wood of the plant is used for

fuel A fuel is any material that can be made to react with other substances so that it releases energy as thermal energy or to be used for work (physics), work. The concept was originally applied solely to those materials capable of releasing chem ...

and

carving Carving is the act of using tools to shape something from a material by scraping away portions of that material. The technique can be applied to any material that is solid enough to hold a form even when pieces have been removed from it, and y ...

Common names

The

English English usually refers to: * English language * English people English may also refer to: Culture, language and peoples * ''English'', an adjective for something of, from, or related to England * ''English'', an Amish ter ...

common names are Indian berry, fishberry, or Levant nut (both referring to the

dried Drying is a mass transfer process consisting of the removal of water or another solvent by evaporation from a solid, semi-solid or liquid. This process is often used as a final production step before selling or packaging products. To be consider ...

fruit, and to the plant by

synecdoche Synecdoche ( ) is a type of metonymy; it is a figure of speech that uses a term for a part of something to refer to the whole (''pars pro toto''), or vice versa (''totum pro parte''). The term is derived . Common English synecdoches include '' ...

) and coca de Levante in

Spanish Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many countries in the Americas **Spanish cuisine **Spanish history **Spanish culture ...

; it is variously known as ligtang, aria (

Mindanao Mindanao ( ) is the List of islands of the Philippines, second-largest island in the Philippines, after Luzon, and List of islands by population, seventh-most populous island in the world. Located in the southern region of the archipelago, the ...

), bayati (

Tagalog Tagalog may refer to: Language * Tagalog language, a language spoken in the Philippines ** Old Tagalog, an archaic form of the language ** Batangas Tagalog, a dialect of the language * Tagalog script, the writing system historically used for Tagal ...

), and variations thereof throughout its natural distribution (the

Philippines The Philippines, officially the Republic of the Philippines, is an Archipelagic state, archipelagic country in Southeast Asia. Located in the western Pacific Ocean, it consists of List of islands of the Philippines, 7,641 islands, with a tot ...

East India East India is a region consisting of the Indian states of Bihar, Jharkhand, Odisha and West Bengal and also the union territory of the Andaman and Nicobar Islands. The states of Bihar and West Bengal lie on the Indo-Gangetic plain. Jharkhan ...

Malaysia Malaysia is a country in Southeast Asia. Featuring the Tanjung Piai, southernmost point of continental Eurasia, it is a federation, federal constitutional monarchy consisting of States and federal territories of Malaysia, 13 states and thre ...

, and

New Guinea New Guinea (; Hiri Motu: ''Niu Gini''; , fossilized , also known as Papua or historically ) is the List of islands by area, world's second-largest island, with an area of . Located in Melanesia in the southwestern Pacific Ocean, the island is ...

). The name "fishberry" comes from the use of the dried fruit as a method of

fishing Fishing is the activity of trying to catch fish. Fish are often caught as wildlife from the natural environment (Freshwater ecosystem, freshwater or Marine ecosystem, marine), but may also be caught from Fish stocking, stocked Body of water, ...

, in which the fish is "stupified and captured"; this method, however, is considered "unsportsmanlike".

References

{{Taxonbar, from=Q2007832 Tropical flora Medicinal plants of Asia Herbal and fungal stimulants Menispermaceae