Ian Wilson (biologist)
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Ian Andrew Wilson is the Hansen Professor of Structural Biology and chair of the Department of Integrative Structural and Computational Biology at the Scripps Research Institute in
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,
California California () is a U.S. state, state in the Western United States that lies on the West Coast of the United States, Pacific Coast. It borders Oregon to the north, Nevada and Arizona to the east, and shares Mexico–United States border, an ...
,
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.


Education

He received his BSc in biochemistry from the
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
in 1971, his PhD degree in molecular biophysics from
Oxford University The University of Oxford is a collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the second-oldest continuously operating u ...
in 1976 under the guidance of
David Chilton Phillips David Chilton Phillips, Baron Phillips of Ellesmere (7 March 1924 – 23 February 1999) was a pioneering, British structural biologist and an influential figure in science and government. Education and early life David was the son of Charles ...
working on the structure of the triosephosphate isomerase. He then did
postdoctoral research A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary acade ...
at
Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
with
Don Craig Wiley Don Craig Wiley (October 21, 1944 – November 15, 2001) was an American structural biologist. Education Wiley received his doctoral degree in biophysics in 1971 from Harvard University, where he worked under the direction of the subsequen ...
from 1977 to 1982 during which he solved the first crystal structure of the
influenza Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These sympto ...
virus
hemagglutinin The term hemagglutinin (alternatively spelt ''haemagglutinin'', from the Greek , 'blood' + Latin , 'glue') refers to any protein that can cause red blood cells (erythrocytes) to clump together (" agglutinate") ''in vitro''. They do this by bindin ...
.


Career and research

After his postdoc positions, he joined the Scripps Research Institute in La Jolla, California, in 1982 as an assistant professor and is currently professor in the department of molecular biology and the Skaggs Institute for Chemical Biology. Hi
laboratory
focuses on the recognition of microbial pathogens by the immune system and has determined over 85 crystal structures of mouse, human, shark, and catalytic antibodies, with a variety of antigens, including steroids, peptides, carbohydrates and viral proteins, such as
HIV-1 The subtypes of HIV include two main subtypes, known as HIV type 1 (HIV-1) and HIV type 2 (HIV-2). These subtypes have distinct genetic differences and are associated with different epidemiological patterns and clinical characteristics. HIV-1 e ...
and
Hepatitis C virus The hepatitis C virus (HCV) is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family ''Flaviviridae''. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer ( hepatoc ...
envelope glycoproteins. His team was reported by the 6 February 2004 edition of
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to have managed to synthesise the
hemagglutinin The term hemagglutinin (alternatively spelt ''haemagglutinin'', from the Greek , 'blood' + Latin , 'glue') refers to any protein that can cause red blood cells (erythrocytes) to clump together (" agglutinate") ''in vitro''. They do this by bindin ...
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
responsible for the 1918 outbreak of
Spanish flu The 1918–1920 flu pandemic, also known as the Great Influenza epidemic or by the common misnomer Spanish flu, was an exceptionally deadly global influenza pandemic caused by the H1N1 subtype of the influenza A virus. The earliest docum ...
. Since 2000, he has directed the Joint Center for Structural Genomics (JCSG) that has pioneered innovative new methods for high throughput structural studies, including x-ray and NMR. The JCSG has determined over 700 structures that focus on the expanding protein universe.


Awards and honours

He was elected as a
Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, incl ...
of London in 2000, a Member of the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
in 2002, a Fellow of the
Royal Society of Edinburgh The Royal Society of Edinburgh (RSE) is Scotland's national academy of science and letters. It is a registered charity that operates on a wholly independent and non-partisan basis and provides public benefit throughout Scotland. It was establis ...
in 2008, a foreign associate of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
in 2016.. He also served on the Life Sciences jury for the
Infosys Prize The Infosys Prize is an annual award granted to scientists, researchers, engineers and social scientists of Indian origin (not necessarily born in India) by the Infosys Science Foundation and ranks among the highest monetary awards for researc ...
in 2014.


Personal life

Ian was born in
Perth, Scotland Perth (; ) is a centrally located Cities of Scotland, Scottish city, on the banks of the River Tay. It is the administrative centre of Perth and Kinross council area and is the historic county town of Perthshire. It had a population of about ...
. His father was a journalist.


References


External links


Ian Wilson Profile at The Scripps Research Institute

Ian Wilson Lab website at The Scripps Research Institute
Year of birth missing (living people) Living people Scripps Research faculty Fellows of the Royal Society Harvard University fellows Alumni of the University of Edinburgh Foreign associates of the National Academy of Sciences American scientists {{US-scientist-stub