IFT81
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Intraflagellar transport protein 81 homolog is a
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''IFT81''
gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
. Together with IFT74/72 it forms a core complex to build IFT particles which are required for
cilium The cilium (: cilia; ; in Medieval Latin and in anatomy, ''cilium'') is a short hair-like membrane protrusion from many types of eukaryotic cell. (Cilia are absent in bacteria and archaea.) The cilium has the shape of a slender threadlike pr ...
formation. Additionally, it interacts with basal body components as
CEP170 Centrosomal protein 170kDa, also known as CEP170, is a protein that in humans is encoded by the ''CEP170'' gene. Function The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major micro ...
which regulates the disassembly of the cilium.


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Further reading

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