Hypobaric Decompression
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Hypobaric decompression is the reduction in ambient pressure below the normal range of sea level atmospheric pressure. Altitude decompression is hypobaric decompression which is the natural consequence of unprotected elevation to altitude, while other forms of hypobaric decompression are due to intentional or unintentional release of pressurization of a
pressure suit A pressure suit is a protective suit worn by high-altitude pilots who may fly at altitudes where the air pressure is too low for an unprotected person to survive, even when breathing pure oxygen at positive pressure. Such suits may be either fu ...
or pressurized compartment, vehicle or habitat, and may be controlled or uncontrolled, or the reduction of pressure in a
hypobaric chamber A hypobaric chamber, or altitude chamber, is a chamber used during aerospace or high terrestrial altitude research or training to simulate the effects of high altitude on the human body, especially hypoxia (low oxygen) and hypobaria (low ambien ...
. Altitude decompression may occur as a decompression from saturation at a lower altitude, or as decompression from an excursion to a lower altitude, in the case of people living at high altitude, making a short duration trip to low altitude, and returning, or a person decompressing from a dive at altitude, which is a special case of
diving decompression Diving most often refers to: * Diving (sport), the sport of jumping into deep water * Underwater diving, human activity underwater for recreational or occupational purposes Diving or Dive may also refer to: Sports * Dive (American football), a ...
. Decompression has physical effects on gas filled spaces and on liquids, particularly when they contain dissolved gases. Physiological effects of decompression are due to these physical effects and the consequential effects on the living tissues, mostly as a result of the formation and growth of bubbles, the expansion of gas filled spaces, and adverse reactions in the injured tissues. Formation and growth of bubbles due to reduced pressure can be due to reduction in
solubility In chemistry, solubility is the ability of a chemical substance, substance, the solute, to form a solution (chemistry), solution with another substance, the solvent. Insolubility is the opposite property, the inability of the solute to form su ...
of dissolved gases as described by
Henry's Law In physical chemistry, Henry's law is a gas law that states that the amount of dissolved gas in a liquid is directly proportional at equilibrium to its partial pressure above the liquid. The proportionality factor is called Henry's law constant ...
, with nucleation and growth of bubbles in supersaturated liquids, or due to
boiling Boiling or ebullition is the rapid phase transition from liquid to gas or vapor, vapour; the reverse of boiling is condensation. Boiling occurs when a liquid is heated to its boiling point, so that the vapour pressure of the liquid is equal to ...
of liquids when the pressure is reduced below the
vapour pressure Vapor pressure or equilibrium vapor pressure is the pressure exerted by a vapor in thermodynamic equilibrium with its condensed phases (solid or liquid) at a given temperature in a closed system. The equilibrium vapor pressure is an indicat ...
for the temperature of the liquid. Both rate of decompression and pressure difference affect the type of injury likely and the severity of the consequences. Barotrauma is more likely to occur for rapid decompression, while decompression sickness is more likely with a large pressure drop, but both can occur simultaneously. Hypoxia risk depends mainly on the oxygen partial pressure after decompression.


Physiological effects

There are three principal physiological effects arising from decompression at altitude:
decompression sickness Decompression sickness (DCS; also called divers' disease, the bends, aerobullosis, and caisson disease) is a medical condition caused by dissolved gases emerging from Solution (chemistry), solution as bubbles inside the body tissues during D ...
due to bubble formation in the tissues similar to those caused by decompression after exposure to pressures higher than sea level atmospheric pressure,
barotrauma Barotrauma is physical damage to body tissues caused by a difference in pressure between a gas space inside, or in contact with, the body and the surrounding gas or liquid. The initial damage is usually due to over-stretching the tissues in ...
caused by the over-expansion of gas-filled spaces, and
altitude sickness Altitude sickness, the mildest form being acute mountain sickness (AMS), is a harmful effect of high altitude, caused by rapid exposure to low amounts of oxygen at high elevation. People's bodies can respond to high altitude in different wa ...
, a manifestation of hypoxia due to the naturally low partial pressure of oxygen in the air at altitude. At higher altitudes, more severe, and potentially fatal hypoxia will occur. Decompression sickness and barotrauma are considered aspects of
decompression illness Decompression Illness (DCI) comprises two different conditions caused by rapid decompression of the body. These conditions present similar symptoms and require the same initial first aid. Scuba divers are trained to ascend slowly from depth to av ...
.


Decompression sickness

Abrupt excursions from sea level to altitudes above without oxygen prebreathing may induce venous gas bubbles, with a 5% probability of symptoms developing at about , at which altitude there is over 50% probability of venous bubbles. By the incidence of venous bubbles exceeds 70%, with a 55% incidence of DCS. These effects may be prevented or delayed by more gradual decompression or by flushing some of the nitrogen from the tissues before decompression by prebreathing a high percentage of oxygen before and during decompression. Altitude decompression sickness often resolves on return to the saturation altitude, but sometimes treatment on elevated concentrations of oxygen is indicated, usually 100% at surface pressure. In more severe cases
hyperbaric oxygen treatment Hyperbaric medicine is medical treatment in which an increase in barometric pressure of typically air or oxygen is used. The immediate effects include reducing the size of gas emboli and raising the partial pressures of the gases present. Initial ...
may be indicated. There is little evidence of altitude decompression sickness occurring among healthy individuals at altitudes below , but it can occur at lower altitudes in underwater divers with sufficient residual inert gas tissue loading after recent diver.


Barotrauma

Barotrauma is physical damage to body tissues caused by a difference in pressure between a gas space inside, or in contact with, the body, and the surrounding gas or liquid. The initial damage is usually due to over-stretching the tissues in tension or shear, either directly by expansion of the gas in the closed space or by pressure difference hydrostatically transmitted through the tissue. Tissue rupture may be complicated by the introduction of gas into the local tissue or circulation through the initial trauma site, which can cause blockage of circulation at distant sites or interfere with normal function of an organ by its presence. Decompression may be intentional or uncontrolled. Intentional decompression includes controlled unpressurised ascent to altitude. Uncontrolled decompression is an unplanned drop in the
pressure Pressure (symbol: ''p'' or ''P'') is the force applied perpendicular to the surface of an object per unit area over which that force is distributed. Gauge pressure (also spelled ''gage'' pressure)The preferred spelling varies by country and eve ...
of a sealed system, such as an
aircraft cabin An aircraft cabin is the section of an aircraft in which passengers travel. Most modern commercial aircraft are pressurized, as cruising altitudes are high enough such that the surrounding atmosphere is too thin for passengers and crew to brea ...
or
hyperbaric chamber A diving chamber is a vessel for human occupation, which may have an entrance that can be sealed to hold an internal pressure significantly higher than ambient pressure, a pressurised gas system to control the internal pressure, and a supply of ...
, and typically results from
human error Human error is an action that has been done but that was "not intended by the actor; not desired by a set of rules or an external observer; or that led the task or system outside its acceptable limits".Senders, J.W. and Moray, N.P. (1991) Human Er ...
,
material fatigue In materials science, fatigue is the initiation and propagation of cracks in a material due to cyclic loading. Once a fatigue crack has initiated, it grows a small amount with each loading cycle, typically producing striations on some parts of ...
,
engineering Engineering is the practice of using natural science, mathematics, and the engineering design process to Problem solving#Engineering, solve problems within technology, increase efficiency and productivity, and improve Systems engineering, s ...
failure, or
impact Impact may refer to: * Impact (mechanics), a large force or mechanical shock over a short period of time * Impact, Texas, a town in Taylor County, Texas, US Science and technology * Impact crater, a meteor crater caused by an impact event * Imp ...
, causing a
pressure vessel A pressure vessel is a container designed to hold gases or liquids at a pressure substantially different from the ambient pressure. Construction methods and materials may be chosen to suit the pressure application, and will depend on the size o ...
to vent into its lower-pressure surroundings or fail to pressurize at all. Such decompression may be classed as ''explosive, rapid'', or ''slow'': * Explosive decompression (ED) is violent and too fast for air to escape safely from the
lung The lungs are the primary Organ (biology), organs of the respiratory system in many animals, including humans. In mammals and most other tetrapods, two lungs are located near the Vertebral column, backbone on either side of the heart. Their ...
s and other air-filled cavities in the body such as the
sinuses Paranasal sinuses are a group of four paired air-filled spaces that surround the nasal cavity. The maxillary sinuses are located under the eyes; the frontal sinuses are above the eyes; the ethmoidal sinuses are between the eyes and the sphenoi ...
and
eustachian tube The Eustachian tube (), also called the auditory tube or pharyngotympanic tube, is a tube that links the nasopharynx to the middle ear, of which it is also a part. In adult humans, the Eustachian tube is approximately long and in diameter. It ...
s, typically resulting in severe to fatal
barotrauma Barotrauma is physical damage to body tissues caused by a difference in pressure between a gas space inside, or in contact with, the body and the surrounding gas or liquid. The initial damage is usually due to over-stretching the tissues in ...
. * Rapid decompression may be slow enough to allow cavities to vent but may still cause serious barotrauma or discomfort. * Slow or gradual decompression occurs so slowly that it may not be sensed before hypoxia sets in, and is unlikely to cause barotrauma, but may cause decompression sickness.


Altitude sickness

Altitude sickness Altitude sickness, the mildest form being acute mountain sickness (AMS), is a harmful effect of high altitude, caused by rapid exposure to low amounts of oxygen at high elevation. People's bodies can respond to high altitude in different wa ...
, also known as acute mountain sickness (AMS), altitude illness, hypobaropathy, or soroche, is a pathological effect of high altitude on humans, caused by acute exposure to low
partial pressure of oxygen Blood gas tension refers to the partial pressure of gases in blood. There are several significant purposes for measuring gas tension. The most common gas tensions measured are oxygen tension (PxO2), carbon dioxide tension (PxCO2) and carbon monoxi ...
and
respiratory alkalosis Respiratory alkalosis is a medical condition in which Tachypnea, increased respiration elevates the blood pH beyond the normal range (7.35–7.45) with a concurrent reduction in arterial levels of carbon dioxide. This condition is one of the four ...
arising from low partial pressure of blood carbon dioxide caused by hyperventilation. Altitude sickness is primarily a consequence of hypoxia. Altitude sickness can be avoided and treated by breathing supplementary oxygen, within limits. Above the
Armstrong limit The Armstrong limit or Armstrong's line is a measure of altitude above which atmospheric pressure is sufficiently low that water boiling, boils at the human body temperature, normal temperature of the human body. Exposure to pressure below this li ...
, the
atmospheric pressure Atmospheric pressure, also known as air pressure or barometric pressure (after the barometer), is the pressure within the atmosphere of Earth. The standard atmosphere (symbol: atm) is a unit of pressure defined as , which is equivalent to 1,013. ...
is sufficiently low that exposed water
boils A boil, also called a furuncle, is a deep folliculitis, which is an infection of the hair follicle. It is most commonly caused by infection by the bacterium ''Staphylococcus aureus'', resulting in a painful swollen area on the skin caused by an ...
at normal
human body temperature Normal human body temperature (normothermia, euthermia) is the typical temperature range found in humans. The normal human body temperature range is typically stated as . Human body temperature varies. It depends on sex, age, time of day, exert ...
. At altitudes above about 50,000 feet (15 km), the
time of useful consciousness Time of useful consciousness (TUC), also effective performance time (EPT), is defined as the amount of time an individual is able to function effectively (e.g. perform aviation, flying duties) in an environment of inadequate oxygen supply. It is th ...
is 9 to 12 seconds. Loss of consciousness is due to hypoxia and is followed by a series of changes to
cardiovascular In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart a ...
and
neurological Neurology (from , "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the brain, the s ...
functions, and eventually death, unless pressure is restored in 60–90 seconds. On Earth, the Armstrong limit is around above
sea level Mean sea level (MSL, often shortened to sea level) is an mean, average surface level of one or more among Earth's coastal Body of water, bodies of water from which heights such as elevation may be measured. The global MSL is a type of vertical ...
, above which atmospheric air pressure drops below 0.0618 atm (6.3
kPa The pascal (symbol: Pa) is the unit of pressure in the International System of Units (SI). It is also used to quantify internal pressure, stress, Young's modulus, and ultimate tensile strength. The unit, named after Blaise Pascal, is an SI ...
, 47
mmHg A millimetre of mercury is a manometric unit of pressure, formerly defined as the extra pressure generated by a column of mercury one millimetre high. Currently, it is defined as exactly , or approximately 1 torr =  atmosphere = &nb ...
, or about 1
psi Psi, PSI or Ψ may refer to: Alphabetic letters * Psi (Greek) (Ψ or ψ), the twenty-third letter of the Greek alphabet * Psi (Cyrillic), letter of the early Cyrillic alphabet, adopted from Greek Arts and entertainment * "Psi" as an abbreviat ...
). The U.S. Standard Atmospheric model sets the Armstrong pressure at an altitude of .


See also

* *


References

{{FAA.Gov, url=http://www.faa.gov/pilots/safety/pilotsafetybrochures/media/dcs.pdf , article=Altitude-induced Decompression Sickness Aviation medicine Decompression theory Decompression practice