Huntington Faxon Willard (born c.1953) is an American

geneticist A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic process ...

. In 2014, he was named to head the

Marine Biological Laboratory The Marine Biological Laboratory (MBL) is an international center for research and education in biological and environmental science. Founded in Woods Hole, Massachusetts, in 1888, the MBL is a private, nonprofit institution that was independent ...

, and is a professor in human genetics at the

University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...

. He stepped down from leading the lab in 2017 to return to research. Willard was elected to the

National Academy of Medicine The National Academy of Medicine (NAM), known as the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Engineerin ...

in 2016. Earlier, beginning in 2003 he was the Nanaline H. Duke Professor of Genome Sciences, the first director of the Institute for Genome Sciences and Policy, and Vice Chancellor for Genome Sciences at

Duke University Medical Center Duke University Hospital is a 1062 -bed acute care facility and an academic tertiary care facility located in Durham, North Carolina, United States. Established in 1930, it is the flagship teaching hospital for the Duke University Health Sy ...

Durham, North Carolina Durham ( ) is a city in the U.S. state of North Carolina and the county seat of Durham County, North Carolina, Durham County. Small portions of the city limits extend into Orange County, North Carolina, Orange County and Wake County, North Carol ...

. Willard graduated from the Belmont Hill School in

Belmont, Massachusetts Belmont is a town in Middlesex County, Massachusetts, United States. It is a western suburb of Boston and is part of the Greater Boston metropolitan area. As of the 2020 U.S. census, its population was 27,295, an increase of 10.4% from 2010. H ...

in 1971. He received his A.B. degree in

biology Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and ...

from

Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...

in 1975 and his Ph.D. from

Yale University Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United Stat ...

in 1979. He did a postdoctoral fellowship in medical genetics at

Johns Hopkins University The Johns Hopkins University (often abbreviated as Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland, United States. Founded in 1876 based on the European research institution model, J ...

from 1979-81. He then held positions at the

University of Toronto The University of Toronto (UToronto or U of T) is a public university, public research university whose main campus is located on the grounds that surround Queen's Park (Toronto), Queen's Park in Toronto, Ontario, Canada. It was founded by ...

from 1982 to 1989,

Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...

from 1989 to 1992, and was Chairman of the Department of Genetics at

Case Western Reserve University Case Western Reserve University (CWRU) is a Private university, private research university in Cleveland, Ohio, United States. It was established in 1967 by a merger between Western Reserve University and the Case Institute of Technology. Case ...

from 1992 to 2002. His current research interests include

genome A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as ...

sciences and their broad implications for medicine and society, human

chromosome A chromosome is a package of DNA containing part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells, the most import ...

structure and function,

X-inactivation X-inactivation (also called Lyonization, after English geneticist Mary Lyon) is a process by which one of the copies of the X chromosome is inactivated in therian female mammals. The inactive X chromosome is silenced by being packaged into ...

and mechanisms of

gene silencing Gene silencing is the regulation of gene expression in a cell to prevent the expression of a certain gene. Gene silencing can occur during either Transcription (genetics), transcription or Translation (biology), translation and is often used in res ...

, and the first reported development of

human artificial chromosome A human artificial chromosome (HAC) is a microchromosome that can act as a new chromosome in a population of human cells. That is, instead of 46 chromosomes, the cell could have 47 with the 47th being very small, roughly 6–10 megabases (Mb) in si ...

s for studies of

gene transfer Horizontal gene transfer (HGT) or lateral gene transfer (LGT) is the movement of genetic material between organisms other than by the ("vertical") transmission of DNA from parent to offspring (reproduction). HGT is an important factor in the e ...

and functional genomics. Studies of the X-chromosome in his laboratory by Carolyn J. Brown led to the discovery of the human XIST gene, the

long noncoding RNA Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that are not translated into protein. This arbitrary limit distinguishes long ncRNAs from small non-coding RNAs, such as mic ...

associated with the inactive X chromosome.

References

External links

Personal site at Duke University

Curriculum Vitae and Bibliography of Huntington F. Willard {{DEFAULTSORT:Willard, Huntington Living people 21st-century American biologists American geneticists Duke University faculty Harvard College alumni Yale University alumni 1950s births University of Chicago faculty Members of the National Academy of Medicine Johns Hopkins University fellows Year of birth missing (living people)